Shinya Yamanaka: Purveyor of Pluripotency [Profiles in Cardiovascular Science]

Until that point, generating a source of patient-identical pluripotent stem cells, a major stepping stone in the quest for stem cell therapies, would only have been possible by cloning a human, generating an embryo, and deriving embryonic stem cells, all of which would involve challenging techniques and a burden of ethical issues.

http://circres.ahajournals.org/content/112/2/233.short?rss=1