LEmed Stem Cell Transplants and Treatments with Type 2 Diabetes Have Shown Positive Results

... cancers, blood diseases and conditions such as diabetes mellitus are among the many conditions where stem cell research, development & treatmen shows positive and effective gains." Stem cell transplants and treatments for individuals diagnosed with ...

http://ift.tt/11GUWp3

LEmed Stem Offering Combination Cell Treatment for Muscular Dystrophy

LEmed, the specialist stem cell, laser therapy, research and distribution group, announced today that it is offering treatment for Muscular Dystrophy. Wan Chai, Hong Kong, December 01, 2014 - - LEmed , the specialist stem cell, laser therapy, research and distribution group, announced today that it is offering treatment for Muscular Dystrophy.

http://ift.tt/11GUYgL

LEmed Participating in Conference on Medical Laser Therapy Bangkok-Thailand

LEmed, the specialist stem cell, laser therapy, and T-cell Modulator research and distribution group, announced today that it will be participating in the upcoming Medical Laser Therapy conference to be held in Bangkok. Wan Chai, Hong Kong, December 01, 2014 - - LEmed , the specialist stem cell, laser therapy, and T-cell Modulator research and distribution group, announced today that it will be participating in the upcoming Medical Laser Therapy conference to be held in Bangkok.

http://ift.tt/11GUYgF

Public education day focuses on stem cells

Liquid-handling robot in the stem cell research laboratory at CBIS on Tuesday, Sept. 9, 2014, at Rensselaer Polytechnic Institute in Troy, N.Y. What exactly are stem cells, and what are they used for? What are the ethical issues surrounding some stem cell research? What clinical trials are available? The University of Texas Health Science Center will hold a free Stem Cell and Regenerative Medicine Public Education Day to address these topics and more.

http://ift.tt/11GRqLB

Longitudinal RNA sequencing of the deep transcriptome during...

... We propose that this data will be a valuable contribution to diverse research efforts in bioinformatics, stem cell research and developmental neuroscience studies. CiteULike organises scholarly (or academic) papers or literature and provides ...

http://ift.tt/1rJjSc1

Marathoners on wheels skate Fiesta Island

... anyone can do it on a longboard." The marathon's proceeds -about $300 - will be donated to a nonembryonic stem cell research company called Summit4StemCell, which is working on treatments for Parkinson's disease. This year's event was also held in ...

http://ift.tt/1vyKbkG

Skateboard marathon held at Fiesta Island

... t beat her personal record. The event did not just highlight this growing sport. It also raised money for stem cell research and the Parkinson's Association.

http://www.10news.com/news/skateboard-marathon-raises-money-for-parkinsons-association-11302014

Protein key to harnessing regenerative power of blood stem cells identified by researchers

... to make stem cells grow. In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member, Dr. John Chute, UCLA scientists have for the first time identified a unique protein that plays a key role in regulating ...

http://www.sciencedaily.com/releases/2014/11/141124143414.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fstem_cells+%28Stem+Cells+News+--+ScienceDaily%29

Report Published: "Follica, Inc. - Medical Equipment - Deals and Alliances Profile"

The company develops therapies for hair follicle, the epicenter for the development and replenishment of human hair and skin disorders. It develops therapeutic products for hair follicle disorders, including hair loss, excessive hair, acne and pigmentation.

http://reports.pr-inside.com/report-published-follica-inc-r4160389.htm

Nail stem cells prove more versatile than press-ons

There are plenty of body parts that don't grow back when you lose them. Nails are an exception, and a new study by a team of USC Stem Cell researchers could help unlock their secrets - and even make it potentially possible to regrow other body tissue.

http://scienceblog.com/75546/nail-stem-cells-prove-versatile-press-ons/

Research findings offer hope for treating Alzheimera s

Dr. Charles P. Gennaula reviews a patient's file with certified nurse practitioner Patty Zamiska in his office in Belle Vernon.

http://www.observer-reporter.com/article/20141130/ALZ/141139999

Recent Study: Cell Expansion Market - Forecast to 2019

... by Product (Reagent, Media, Serum, Bioreactors, Centrifuge), Cell Type (human, animal), Application (Stem Cell Research, Regenerative Medicine, Clinical Diagnostics), End User (Hospital, Biotechnology, Cell Bank) - Forecast to 2019 The global cell ...

http://reports.pr-inside.com/recent-study-cell-expansion-market-r4160232.htm

PhD: A genomic and functional approach to study neurodevelopmental disorders

The Center for Human Genetics at KU Leuven has a long tradition in clinical-molecular research on cognitive disorders with the presence of a large and unique patient collection and the identification of many new syndromes and genes. However, in depth functional studies on each of these neurodevelopmental genes are severely hampered in humans because of lack of the relevant tissue.

http://ift.tt/1vuOnSj

Cell Isolation/Cell Separation Market worth $5.1 Billion by 2019 - New...

... for production of personalized medicine, stem cell and cancer research. Increasing government support for stem cell research in terms of grants and funding will enable research laboratories to opt for advanced products such as magnetic activated ...

http://ift.tt/12d9Zqy

Patients waiting for stem cell match counting on Canadians

"Just as Black Friday and Cyber Monday kick off the holiday shopping season, Giving Tuesday is dedicated to philanthropy and marks the opening day of giving season," says "Giving Tuesday is an excellent opportunity for the community phase of our For All Canadians campaign. Building a national public cord blood bank will transform stem cell transplantation in , it is discarded as medical waste.

http://ift.tt/1AZH9Jt

Stem Cell Advocacy And The Patient's Perspective

... of Medicine , which she and stem cell advocate Roman Reed helped to establish, to help raise funds for stem cell research in her home state. But that's getting ahead of the story. Inevitable Collision starts as an up close and personal account of ...

http://ift.tt/1yqIEho

7 Cutting-Edge Techniques That Will Impact Your Next Hair Transplant

You may not think scientific breakthroughs are changing the face of hair transplants; but think again. Utilizing up-to-the minute medical research and innovative techniques , today's hair transplants have become faster, more efficient, and safer than ever before.

http://ift.tt/1pvQy7n

Northeastern University and Phase Holographic Imaging Establish a...

The agreement extends the ongoing PHI's HoloMonitor technology evaluation program at to create a Holographic Imaging Cytometry Program of Excellence - an application development hub and educational resource providing training programs for scientists using time-lapse cytometry . PHI's HoloMonitor technology enables analysis of label-free cellular specimens utilizing the principles of holography.

http://ift.tt/1FB2usC

'Chatty' cells help build the brain

Fluorescence microscopy image of a mouse cortex during brain development. Blue cells are deep-layer neurons, green cells are Foxg1 active cells and red cells are upper-layer neurons.

http://ift.tt/1yql4B9

Stem Cell Therapy for Regenerative Medicine

The confusion surrounding stem cells starts at the root, with the most basic but difficult-to-answer question, "What is a stem cell?" Get answers to this and other questions related to stem cell research and therapies. Stem cells are an exciting biological technology for scientists, engineers, and physicians, but more significantly, stem cell therapies are a source of hope for millions of ailing patients.

http://ift.tt/1FB2uc3

Northeastern University and Phase Holographic Imaging Establish a...

The agreement extends the ongoing PHI's HoloMonitorA technology evaluation program at to create a Holographic Imaging Cytometry Program of Excellence - an application development hub and educational resource providing training programs for scientists using time-lapse cytometry . PHI's HoloMonitor technology enables analysis of label-free cellular specimens utilizing the principles of holography.

http://ift.tt/1FAYbLW

UCLA researchers unlock protein key to harnessing regenerative power of blood stem cells

In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member, Dr. John Chute, UCLA scientists have for the first time identified a unique protein that plays a key role in regulating blood stem cell replication in humans. This discovery lays the groundwork for a better understanding of how this protein controls blood stem cell growth and regeneration, and could lead to the development of more effective therapies for a wide range of blood diseases and cancers .

http://ift.tt/1vXf3wH

More donors flood in for Emily appeal

THE WELSH Blood Service is calling on members of the public to sign up to become a bone marrow donor as the appeal to find a donor for Emily Clark continues. A spokeswoman for the Welsh Blood Service said it is 'vital' for people to sign up to help people from anywhere in the world.

http://ift.tt/1puDQpi

The promise of induced pluripotent stem cells in research and therapy.

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. The field of stem-cell biology has been catapulted forward by the startling development of reprogramming technology.

http://ift.tt/1AXHD2S

Faversham schoolgirl Roisin Kelleher discovers mother Anntoinette and ...

Roisin's mother Anntoinette and brother Cian are both a match for her stem-cell treatment meaning the operation can definitely go ahead. The 19-year-old, of Whitstable Road, and her family, have arranged to travel to the Dominican Republic for the procedure on January 18 and with a bit of luck she will be healthy enough to travel.

http://ift.tt/1yinMrz

Readers respond to plea for donors

MORE than 280 people from Gwent have been touched by Emily Clark's plea for bone marrow donors after The South Wales Argus highlighted her story. Cwmbran's Emily Clark, 17, is urging people to sign up as bone marrow donors as she searches for a life-saving match after being told last week her cancer, non-Hodgkin lymphoma, had returned.

http://ift.tt/1zzM67G

Bulletin from Annual General Meeting of Diamyd Medical AB

The following items were addressed at the Annual General Meeting of Diamyd Medical AB held today: Diamyd Medical's President and CEO Peter Zerhouni gave a retrospective view of the past year and summarized the most significant events that took place during the fiscal year and after year-end. The Company's income statement and balance sheet were adopted and the Board members and the Chief Executive Officer were discharged from liability for the 2013/2014 fiscal year.

http://ift.tt/1voxTd8

Endonuclease G preferentially cleaves...

We have identified an activity that preferentially catalyzes the cleavage of double-stranded 5hmC-modified DNA. Using biochemical methods we purified this activity from mouse liver extracts and demonstrate that the enzyme responsible for the cleavage of 5hmC-modified DNA is Endonuclease G .

http://ift.tt/1rrZY5h

Binding site discovery from nucleic acid sequences by discriminative learning of hidden Markov models

We present a discriminative learning method for pattern discovery of binding sites in nucleic acid sequences based on hidden Markov models. Sets of positive and negative example sequences are mined for sequence motifs whose occurrence frequency varies between the sets.

http://ift.tt/1rrZWdy

Mutation, clonal fitness and field change in epithelial carcinogenesis.

Developments in lineage tracing in mouse models have revealed how stem cells maintain normal squamous and glandular epithelia. Here we review recent quantitative studies tracing the fate of individual mutant stem cells which have uncovered how common oncogenic mutations alter cell behaviour, creating clones with a growth advantage that may persist long term.

http://ift.tt/1voO9vW

Plymouth professor awarded grant to find effective treatment for patients with mantle cell lymphoma

Professor Simon Rule, Professor in Haematology at Plymouth University Peninsula Schools of Medicine and Dentistry and Consultant Haematologist at Plymouth Hospitals NHS Trust, has been awarded a significant grant by Cancer Research UK to carry out a research study into the treatment of older patients with mantle cell lymphoma. The award, which is in the region of 600,000 and will be split over 90 months, will enable Professor Rule to lead a national research study to look at and compare the efficacy and side effects of using a BTK inhibiting drug in a trial against standard chemotherapy.

http://ift.tt/11XVVCa

Stem Cell Biology Researcher

We are looking for outstanding candidates to join the Lab of Stem Cell Biology and Neurodegeneration lead by Dr Evangelos Kiskinis at the Feinberg Medical School, Department of Neurology at Northwestern University in Chicago. Positions are available at the Postdoctoral and Lab Technician Levels.

http://ift.tt/1FuNpbZ

Tremendous progress in the development of skin stem cell treatments for butterfly children

Scientists at IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences in Vienna have made a major advancement towards a future therapy for butterfly children. A treatment with fibroblasts generated from induced pluripotent stem cells has been highly successful in mice.

http://ift.tt/1249P4O

First time in India, Kerala hospital performs rare treatment for acute blood cancer

Nineteen-year-old Neena was suffering from acute blood cancer or acute myeloid leukaemia. Her disease slipped into a life-threatening stage even after two cycles of chemotherapy.

http://ift.tt/11xcDrh

Research team proves the efficacy of new drug against stem cells that ...

... tests with actual patients in the near future. Click 'references' tab above for source. Visit our Stem Cell Research category page for the latest news on this subject. MLA University of Granada. "Research team proves the efficacy of new drug against ...

http://ift.tt/1rpOY8m

Researchers show that iPS cells can be used to edit genetic mutations that cause DMD

Researchers at the Center for iPS Cell Research and Application , Kyoto University, show that induced pluripotent stem cells can be used to correct genetic mutations that cause Duchenne muscular dystrophy . The research, published in Stem Cell Reports , demonstrates how engineered nucleases, such as TALEN and CRISPR, can be used to edit the genome of iPS cells generated from the skin cells of a DMD patient.

http://ift.tt/1vocxOk

Tremendous progress in the development of skin stem cell treatments for butterfly children

Scientists at IMBA - Institute of Molecular Biotechnology of the Austrian Academy of Sciences in Vienna have made a major advancement towards a future therapy for butterfly children. A treatment with fibroblasts generated from induced pluripotent stem cells has been highly successful in mice.

http://ift.tt/1uL8970

SALL4, a novel marker for human gastric carcinogenesis and metastasis

Correspondence: Professor W Xu or Professor H Qian, School of Medical Science and Laboratory Medicine, Jiangsu University, 301 Xuefu Road, Zhenjiang, Jiangsu 212013, China. E-mail: icls@ujs.edu.cn or lstmmmlst@163.com SALL4, a zinc-finger transcriptional factor for embryonic stem cell self-renewal and pluripotency, has been suggested to be involved in tumorigenesis.

http://ift.tt/1y4rgAj

Facebook 'toasties' spark cancer fund campaign

A LOVE story of two childhood sweethearts and a piece of toast has spawned a huge fundraising effort after one was diagnosed with a rare cancer on Valentine's Day. Phillip and Leza Starkey, both 47, first met at a Liverpool disco when they were just 15, getting engaged three years later.

http://ift.tt/1AVa2GI

Neediest Families Fund: Family battles through 2-year-old son's cancer

Last November, Athyn was a 14-month-old baby with a smile well beyond his years. And for the past few weeks, he wasn't feeling well and was constipated.

http://ift.tt/1AVa2Gy

Researchers uncover easily detectable, 'pre-malignant' state in the blood

Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and Harvard-affiliated hospitals have uncovered an easily detectable, "pre-malignant" state in the blood that significantly increases the likelihood that an individual will go on to develop blood cancers such as leukemia, lymphoma, or myelodysplastic syndrome. The discovery, which was made independently by two research teams affiliated with the Broad and partner institutions, opens new avenues for research aimed at early detection and prevention of blood cancer.

http://ift.tt/1FsXjdY

Randomised, double-blind, placebo-controlled trial of oral budesonide ...

Randomised, double-blind, placebo-controlled trial of oral budesonide for prophylaxis of acute intestinal graft-versus-host disease after allogeneic stem cell transplantation BackgroundGastrointestinal graft?versus-host disease is a potentially life-threatening complication after allogeneic stem cell transplantation . Since therapeutic options are still limited, a prophylactic approach seems to be warranted.MethodsIn this randomised, double-blind-phase III trial, we evaluated the efficacy of budesonide in the prophylaxis of acute intestinal GvHD after SCT.

http://ift.tt/1yjKUa7

CSU Researchers Using Stem Cell Therapy To Treat Kidney Disease In Cats

Researchers at Colorado State University are using stem cell therapy to treat kidney disease in cats. They're hoping to learn if stem cells can stop the progression of the disease.

http://ift.tt/1vPP9e4

Acclaimed actor Michael York to keynote amyloidosis event

Critically acclaimed film and stage actor Michael York will share the personal story of his battle with amyloidosis at a special presentation at the Froedtert & the Medical College of Wisconsin Cancer Center Tuesday, December 9 at 10:30 a.m. The event, titled Michael York launches RENEWAL , welcomes patients, families and interested parties to learn more about amyloidosis and to meet York, who played the title role in the Academy Award winning science fiction film Logan's Run. The name "RENEWAL" was selected to reflect the concept of life renewal for patients.

http://ift.tt/1vPP6it

Global apheresis equipment market: Revenue driven by increased...

The global market for Apheresis continues to witness steady growth driven by the rising adoption of therapeutic and donor apheresis. Key factors driving growth of donor apheresis include rising awareness over the safety of blood donation through apheresis, and growing number of platelet donations , plasma donations , leukocytes donation and double red cell donation, among others.

http://ift.tt/1vPP8Xw

An Interview with Bob Hariri of Human Longevity, Inc.

We will match your research donations! The causes of aging and frailty might be controlled within our lifetimes as a result of programs initiated at the SENS Research Foundation. Support this work and we will match the first $50,000 donated before the end of 2014 at $2 for every $1 you provide.

http://ift.tt/1yZWshd

The Regeneration Generation: A Conversation With Bob Hariri,...

Bob Hariri, M.D., Ph.D., is the vice chairman of Human Longevity Inc. , a genomics and cell-therapy diagnostics and therapeutics company he co-founded in 2013 with Craig Venter and Peter Diamandis, which is focused on extending the healthy, high-performance human lifespan. Utilizing technological advancements in genomics, bioinformatics, computing and cell therapy, HLI plans to develop therapeutic solutions to some of the most complex yet actionable diseases, such as cancer, heart disease and dementia.

http://ift.tt/1rmovZd

Two studies identify a detectable, pre-cancerous state in the blood

The discovery, which was made independently by two research teams affiliated with the Broad and partner institutions, opens new avenues for research aimed at early detection and prevention of blood cancer. Findings from both teams appear this week in the New England Journal of Medicine .

http://ift.tt/1vml58l

Scientists use stem cells to correct skin defects

New research has found evidence that stem cells could be used to correct genetic defects in skin and to treat certain rare diseases. Three separate studies by scientists in the US, Europe and Japan have raised hopes that the methods could be used to develop treatments for a range of problems, including epidermolysis bullosa.

http://ift.tt/1FsGnCu

Efficacy of new drug against stem cells that provoke onset, growth of cancer, metastasis

An team of researchers has demonstrated the efficacy of a new drug against cancerogenic stem cells, which cause the onset and development of cancer, of relapse after chemotherapy and metastasis. This drug, called Bozepinib, has proved to be effective in tests with mice, they report.

http://ift.tt/1uXzNTo

Two studies identify a detectable, pre-cancerous state in the blood

Researchers from the Broad Institute of MIT and Harvard, Harvard Medical School, and Harvard-affiliated hospitals have uncovered an easily detectable, "pre-malignant" state in the blood that significantly increases the likelihood that an individual will go on to develop blood cancers such as leukemia, lymphoma, or myelodysplastic syndrome. The discovery, which was made independently by two research teams affiliated with the Broad and partner institutions, opens new avenues for research aimed at early detection and prevention of blood cancer.

http://ift.tt/1vml1Wm

The Miami Stem Cell Treatment Center Announces Adult Stem Cell Public ...

The Miami Stem Cell Treatment Center announces a series of free public seminars on the use of adult stem cells for various chronic, degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief and Dr. Nia Smyrniotis, Medical Director.

http://ift.tt/11V8BcO

What's Happening, Nov. 27 2014

Galatoire's Restaurant, 209 Royal St., New Orleans, plans to ring in the new year with a five-course Nicholas Feuillatte Champagne dinner. Located on Galatoire's second floor with a balcony overlooking Bourbon Street, the New Year's Eve Champagne dinner will be $175 per person, exclusive of tax and gratuity.

http://ift.tt/1xHC4ix

NeoStem, Inc. To Host Key Opinion Leader Event Webcast On December 1, 2014

NeoStem, Inc. , a biopharmaceutical company developing novel cell based therapeutics, announced today that it will host a Key Opinion Leader event webcast on Monday, December 1, 2014 from 4:30 to 5:30 PM EST. The webcast will feature a presentation by Timothy Henry, MD, Director of Cardiology at the Cedars-Sinai Heart Institute, who will discuss the significance of the Phase 2 PreSERVE AMI clinical trial, the results of which were previously announced on November 17th.

http://ift.tt/1y2jerH

Cesca Therapeutics Invited To Present At Conference And The

Cesca Therapeutics Inc. , an autologous cell-based regenerative medicine company announced today that the Company will present at the LD Micro Conference on Tuesday, December 2nd and at the World Stem Cell Summit on Wednesday, December 3rd. The conference hosts 100 companies and provides them with the opportunity to showcase their businesses among high quality private and institutional investors.

http://ift.tt/1y2jerx

Fate Therapeutics To Present At Piper Jaffray 26th Annual Healthcare Conference

Fate Therapeutics, Inc. , a biopharmaceutical company engaged in the discovery and development of adult stem cell modulators to treat orphan diseases, announced today that Christian Weyer, M.D., M.A.S., President and Chief Executive Officer, will present an overview of the company's programs at the Piper Jaffray 26th Annual Healthcare Conference on Tuesday, December 2nd, 2014 at 12:10 pm EST in New York, NY. A live webcast can be accessed under "Events & Presentations" in the Investors and Media section of the Company's website at http://ift.tt/1psDMU5 .

http://ift.tt/15zq5gq

Stem Cells Hold Promise for Skin Disease Treatment

Scientists have used stem cells to make fresh, healthy human skin in a laboratory dish, offering a new route for treating a group of debilitating skin diseases. The latest research is another advance in the quest to harness the power of master cells, known as stem cells, to treat intractable ailments.

http://ift.tt/1ChJUY2

Stem cells show potential for treating rare skin disease

Researchers have taken several steps toward using stem cells to treat a rare genetic disease that leaves people with skin so fragile it blisters at the slightest touch. A trio of lab and animal studies reported today could help pave the way for a clinical trial for the disorder, called epidermolysis bullosa .

http://ift.tt/15zJHBd

iPS cells used to correct genetic mutations that cause muscular dystrophy

This image shows immunofluorescence staining of skeletal cells differentiated from DMD-iPS cells. Untreated DMD skeletal cells do not express dystrophin due to the deletion of exon 44. However, after any of the three correction strategies are applied to iPS cells, differentiation into skeletal cells results in normal dystrophin expression.

http://ift.tt/1pnNbiH

City Of Hope Researchers Unlock The Potential Of The Immune System To Fight Cancer

If a patient's immune system could be sufficiently bolstered, it could ultimately be a powerful weapon against blood cancers and other diseases. That approach, known widely as immunotherapy, is much more than a narrow field of study at City of Hope.

http://ift.tt/1FszgKm

Five scientists nab awards for high-risk, high-return research

The NIH has announced that Sean Wu will receive a Pioneer Award; Michael Bassik will receive a New Innovator Award; and David Chan, Michael Angelo and Eric Nelson will receive Early Independence Awards. Five scientists at the School of Medicine have received awards totaling $7.75 million to pursue high-risk, high-reward research, the National Institutes of Health announced today.

http://ift.tt/1s5cd6J

Ontario announces funding for stem cell institute

"Ontario has an amazing research community that I think makes it the best place in the world for regenerative medicine", said UBC professor Fabio Rossi, Canada Research Chair in Regenerative Medicine. "We do need to continue to invest because the world is competitive.

http://ift.tt/1vk2Tv1

iPS cells used to correct genetic mutations that cause muscular dystrophy

This image shows immunofluorescence staining of skeletal cells differentiated from DMD-iPS cells. Untreated DMD skeletal cells do not express dystrophin due to the deletion of exon 44. However, after... Researchers at the Center for iPS Cell Research and Application , Kyoto University, show that induced pluripotent stem cells can be used to correct genetic mutations that cause Duchenne muscular dystrophy .

http://ift.tt/1vjT549

Funding to investigate an alternative to chemotherapy

Professor Simon Rule, Professor in Haematology at Plymouth University Peninsula Schools of Medicine and Dentistry and Consultant Haematologist at Plymouth Hospitals NHS Trust, has been awarded a significant grant by Cancer Research UK to carry out a research study into the treatment of older patients with mantle cell lymphoma. The award, which is in the region of 600,000 and will be split over 90 months, will enable Professor Rule to lead a national research study to look at and compare the efficacy and side effects of using a BTK inhibiting drug in a trial against standard chemotherapy.

http://ift.tt/1Fseiv4

Blow for Emily in race to find donor match

TEENAGER Emily Clark's battle to find a donor to save her life was dealt a blow yesterday - with news her younger sister is not a match for her. Emily, 17, from Cwmbran, needs a bone marrow transplant after being told last week that her cancer, Non Hodgkin Lymphoma, had returned.

http://ift.tt/15ye6Qp

November Tip Sheet from Cedars-Sinai Medical Center

Following is the November 2014 tip sheet of story ideas from Cedars-Sinai Medical Center. To arrange interviews, please contact the individual listed.

http://ift.tt/1xFWbhg

Ontario Government Fnding Stem Cell Research

... help the province commercialize new discoveries and benefit from significant economic opportunities in stem cell research. "Ontario is an international leader in stem cell and regenerative medicine research. This investment by the Government of ...

http://ift.tt/1y1lcbN

Transcriptome-Wide Survey of Mouse CNS-Derived Cells Reveals...

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Monoallelic expression is an integral component of regulation of a number of essential genes and gene families.

http://ift.tt/1y1ldfZ

Research and Markets: Global Regenerative Medicines Market 2014-2020...

The global regenerative medicine market will reach $ 67.6 billion by 2020 from $16.4 billion in 2013, registering a CAGR of 23.2% Regenerative medicines have the unique ability to repair, replace and regenerate tissues and organs, affected due to some injury, disease or due to natural aging process. These medicines are capable of restoring the functionality of cells and tissues.

http://ift.tt/1uGTklP

NFL star whose daughter's battle with cancer captured hearts of...

Angry: Channing Smythe, the mother of Devon Still's four-year-old daughter, Leah, has claimed that he hasn't paid child support to her in months The NFL star whose daughter's battle with cancer is the league's feel-good story of the season has not paid child support in months, the girl's mother claims. Devon Still, who plays defensive tackle for the Cincinnati Bengals, has not paid any child support for his four-year-old daughter Leah since July, according to her mother Channing Smythe.

http://ift.tt/1pmusUE

Cardio3 BioSciences Announces the Nomination of Three Co-principal...

Cardio3 BioSciences Announces the Nomination of Three Co-principal Investigators for its CHART-2 Phase III Clinical Trial of C-Cure for the Treatment of Heart Failure will be Co-Principal Investigators of the phase III clinical trial CHART-2, authorized by the FDA in January : CARD ), a leader in the discovery and development of regenerative, protective and reconstructive therapies, announces today the appointment of its three Co-Principal Investigators for the CHART-2 study , authorized in CHART-2 is Cardio3 BioSciences' second Phase III trial for C-Cure , the first and only stem cell therapeutic using guided stem cells for the condition of congestive heart failure. C-Cure is currently in a Phase III clinical trial in .

http://ift.tt/1vMEIZu

Researcher turns skin cells into pain sensing neurons

After more than six years of intensive effort, and repeated failures that made the quest at times seem futile, Harvard Stem Cell Institute researchers at Boston Children's Hospital and Harvard's Department of Stem Cell and Regenerative Biology have successfully converted mouse and human skin cells into pain sensing neurons that respond to a number of stimuli that cause acute and inflammatory pain. This image shows human noxious stimulus detecting sensory neurons produced by converting skin cells with a set of five genes to this new fate -- enabling study of 'pain' in a dish.

http://ift.tt/1yb0hR7

Cardio3 BioSciences Announces the Nomination of Three Co-principal...

C-CureA is currently in a Phase III clinical trial in . The CHART-2 Phase III trial is a prospective, multi-centre, randomized, sham-controlled, patient- and evaluator-blinded study comparing treatment with C-CureA to a sham treatment.

http://ift.tt/1uVDOYA

Karma Koffee

You know the basics of what goes into making a cup of coffee...beans...water. Well for a new Omaha business, add to the recipe, a healthy dose of life, or, what they call "Karma".

http://ift.tt/1vfx4mO

Ontario announces funding for stem cell institute

... therapies and cures while also growing our economy and securing our reputation as a leader in stem cell research," says Reza Moridi, Ontario Minister of Research and Innovation. The Ontario Institute for Regenerative Medicine will bring together ...

http://ift.tt/1xZefIi

Not Everyone Likes Mitochondrial DNA Damage as a Theory of Aging

We will match your research donations! The causes of aging and frailty might be controlled within our lifetimes as a result of programs initiated at the SENS Research Foundation. Support this work and we will match the first $50,000 donated before the end of 2014 at $2 for every $1 you provide.

http://ift.tt/1ARd9zg

A little karma with your coffee?

An Omaha coffee shop is making its product with more than just beans and hot water, it adds a healthy dose of life to the recipe. They want their coffee shop to be a place where people can find balance.

http://ift.tt/1AR8ldq

Re-purposing a drug to help cancer patients keep platelet counts up

One of the most common drugs to fight blood cancer, Multiple Myeloma, causes patients' platelets to decrease. A low platelet count means delaying treatment or taking lower doses of the drug - which is bad news for cancer patients.

http://ift.tt/15rBeQi

Stem Cell Markets - new market research report published

A stem cell is an extraordinary type of cell that has the ability to self-renew for long periods of time and to differentiate into specialized cells under appropriate physiological or experimental conditions. Traditionally, stem cells have been classified as either embryonic, adult stem cells.Recent understanding of stem cell biology may provide new approaches for the treatment of a number of diseases as well as tissue/organ injuries, including cardiovascular disease, neurological disease, musculoskeletal disease, diabetes and hematopoietic disorders.

http://ift.tt/1uDzUhP

Binding site discovery from nucleic acid sequences by discriminative learning of hidden Markov models

We present a discriminative learning method for pattern discovery of binding sites in nucleic acid sequences based on hidden Markov models. Sets of positive and negative example sequences are mined for sequence motifs whose occurrence frequency varies between the sets.

http://ift.tt/1AQfn1R

Transfusions may be key to helping younger victims of sickle cell disease

Twelve-year-old Alexis Haynes has come a long way, at age six a sudden stroke put her in a coma for a full month. "The doctors told us that she wouldn't be able to walk, she wouldn't be able to talk, she wouldn't remember us," said Kelvin Hayes, Alexis' father.

http://ift.tt/1rpUq5r

Creating Pain-sensing Neurons

After more than six years of intensive effort, including repeated failures that at times made the quest seem futile, Harvard Stem Cell Institute researchers at Boston Children's Hospital and at Harvard's Department of Stem Cell and Regenerative Biology have successfully converted mouse and human skin cells into pain-sensing neurons that respond to a number of stimuli that cause acute and inflammatory distress. This "disease in a dish" model of pain reception may advance the understanding of different types of pain, identify why individuals differ in their pain responses or their risk of developing chronic pain, and make possible the development of improved drugs to treat pain.

http://ift.tt/15q9OKA

Cloning Pioneer Proposes Global Network of IPS Cell Banks

Ian Wilmut, father of the cloned Dolly the Sheep, is now proposing to father a global induced pluripotent stem cell handbook- to go with a proposed new global network of iPS cell haplobanks. With a network of global iPS cell banks- and global iPS cell rules- "everybody in the world would have [safe] stem cells somewhere that produce a reduced immune response," Wilmut told the New York Stem Cell Foundation conference recently.

http://ift.tt/15q9OdM

Cellular Biomedicine Group To Present Knee Osteoarthritis Clinical Trial Data At

Cellular Biomedicine Group Inc. , a biomedicine firm engaged in the development of effective treatments for degenerative and cancerous diseases, today announced that Dr. William Cao, Chief Executive Officer of the Company, will present "48-week Clinical Results from Phase IIa Trial of Human Adipose Mesenchymal Progenitor Cell Treatment for Knee Osteoarthritis" at the 10th Annual World Stem Cell Summit and RegMed Capital Conference held at the Marriott Rivercenter, San Antonio, Texas, December 3-5, 2014. "We look forward to discussing the data analysis comprising of WOMAC, NRS-11, SF-36 and KSCRS indices.

http://ift.tt/1FoXzsz

Vegetable oil ingredient key to destroying gastric disease bacteria

... ... Led by Dr. Hanna Mikkola, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA scientists have discovered a protein that is integral to the self-replication of hematopoietic stem ... A Jackson ...

http://ift.tt/1AOHxul

Pope Francis urges Europeans to reject 'throwaway culture'

... poor. More recently, Francis has turned his attention to bioethics issues, describing abortion, embryonic stem cell research and euthanasia as "playing with life" and "a sin against God." But this was the first time he has delivered his message on ...

http://ift.tt/1uCfLIU

HIV/AIDS Drugs Could Be Repurposed To Treat Age-Related Macular...

HIV/AIDS Drugs Could Be Repurposed to Treat Age-Related Macular Degeneration; Study Published Today in Science LEXINGTON, Ky. - A landmark study published today in the journal Science by an international group of scientists, led by the laboratory of Dr. Jayakrishna Ambati, professor and vice chair of the Department of Ophthalmology & Visual Sciences at the University of Kentucky, reports that HIV/AIDS drugs that have been used for the last 30 years could be repurposed to treat age-related macular degeneration , as well as other inflammatory disorders, because of a previously undiscovered intrinsic and inflammatory activity those drugs possess.

http://ift.tt/15nG9lv

Pain-Sensing Neurons Created From Human, Mouse...

Two different teams of researchers, one led by scientists from The Scripps Research Institute and the other involving members of the Harvard Stem Cell Institute have discovered ways to create the neurons that detect pain, itch and other sensations in laboratory conditions out of human and mouse skin cells. The TSRI study , which was published online Monday in the journal Nature Neuroscience , used what the authors referred to as a simple technique to create neurons that normally reside in clusters called dorsal root ganglia along the outer spine.

http://ift.tt/1vc28nv

UCLA Researchers Identify Protein Key To The...

Led by Dr. Hanna Mikkola, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research , UCLA scientists have discovered a protein that is integral to the self-replication of hematopoietic stem cells during human development. The discovery lays the groundwork for researchers to generate hematopoietic stem cells in the lab that better mirror those that develop in their natural environment.

http://ift.tt/1vc2731

Team uses e-health records to search for hidden drug benefits

... r, ... Led by Dr. Hanna Mikkola, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA

http://ift.tt/11sP3Mf

Yogurt could lower Type 2 diabetes risk; pain in petri dish: health news

Nuitritionists find plenty to love about yogurt but how about this: New research has discovered a link between eating yogurt and a lower risk for Type 2 diabetes, the seventh leading cause of death in the United States. A study published in BMC Medicine found that yogurt appeared to lower the risk of Type 2 diabetes.

http://ift.tt/1Fo9nLQ

Ocata Therapeutics to Present at 26th Annual Piper Jaffray Health Care Conference

Ocata Therapeutics, Inc., today announced that Paul Wotton, Ph.D., President and Chief Executive Officer, will present a company overview at the 26th Annual Piper Jaffray Health Care Conference on Tuesday, December 2, 2014 at 9:30 a.m. EST in New York City. A live audio webcast of the presentation will be available via the "Investor Relations" page of the Ocata website, www.ocata.com .

http://ift.tt/1roxRy8

Pope Francis urges Europeans to reject a throwaway culturea

... poor. More recently, Francis has turned his attention to bioethics issues, describing abortion, embryonic stem cell research and euthanasia as "playing with life" and "a sin against God." But this was the first time he has delivered his message on ...

http://ift.tt/1zUG6Hi

Pain in a dish

After more than six years of intensive effort, and repeated failures that made the quest at times seem futile, Harvard Stem Cell Institute researchers at Boston Children's Hospital and Harvard's Dept. of Stem Cell and Regenerative Biology have successfully converted mouse and human skin cells into pain-sensing neurons that respond to a number of stimuli that cause acute and inflammatory pain.

http://ift.tt/1xXn6Km

Regen BioPharma Acquires University of Toronto Cancer Stem Cell Intellectual Property

Inventors of the intellectual property on which this patent application was filed are University of Toronto Hematologist Dr. Richard Wells and Dr. Christine Ichim, Senior Research Consultant for Regen BioPharma. The invention is based on findings that leukemic stem cells, which are capable of giving rise to aggressive leukemias, contained high levels of the NR2F6 gene, whereas leukemic cells that are less aggressive and cannot give rise to disease lack this gene.

http://ift.tt/1trraLA

Okyanos Adopts WAL/ body-jet eco for Use in Cell Therapy

Patient recovery time boosted by use of less-invasive water-assisted device for harvesting of adipose-derived adult stem cells The body-jet eco performed flawlessly as expected and we feel it meets our tough standards. -- Dr. Todd Malan, Chief Therapy Officer & General Surgeon at Okyanos Okyanos , the leader in cell therapy, announced the adoption of body-jet eco for use in the harvesting of adult stem cells for use in cell therapy.

http://ift.tt/1ravQek

Researchers identify protein key to the development of blood stem cells

Led by Dr. Hanna Mikkola, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA scientists have discovered a protein that is integral to the self-replication of hematopoietic stem cells during human development. The discovery lays the groundwork for researchers to generate hematopoietic stem cells in the lab that better mirror those that develop in their natural environment.

http://ift.tt/1vajjpE

Remotely controlled magnetic nanoparticles stimulate stem cells to regenerate bones

Researchers in bone tissue regeneration believe they have made a significant breakthrough for sufferers of bone trauma, disease or defects such as osteoporosis . Medical researchers from Keele University and Nottingham University have found that magnetic nanoparticles coated with targeting proteins can stimulate stem cells to regenerate bone.

http://ift.tt/1v9Ku3R

Developmental biology of the pancreas: a comprehensive review.

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Pancreatic development represents a fascinating process in which two morphologically distinct tissue types must derive from one simple epithelium.

http://ift.tt/1yb4vsM

Search for Cwmbran teen's donor hero continues

DESCRIBED by her mum as a "needle in a haystack", the search for a bone marrow donor for a Cwmbran teen continues as she battles cancer. Emily Clark, 17, who is currently receiving chemotherapy treatment at the Teenage Cancer Trust at the University Hospital of Wales, needs a bone marrow transplant after she was last week dealt the terrible news that her cancer, non-Hodgkin lymphoma, had returned.

http://ift.tt/1yb4vcq

The versatility of nail stem cells

... of the hair follicle or sweat gland," said Kobielak. Click 'references' tab above for source. Visit our Stem Cell Research category page for the latest news on this subject. MLA University of Southern California - Heal. "The versatility of nail stem ...

http://ift.tt/1rn8eh7

Rare stem cells identified that give rise to chronic tissue scarring

Harvard Stem Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes , lung disease, high blood pressure , kidney disease, and other conditions. The buildup of scar tissue is known as fibrosis.

http://ift.tt/1rmUgMi

Pluripotent cells created by nuclear transfer can prompt immune reaction, researchers find

Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell's mitochondria, according to a study in mice by researchers at the Stanford University School of Medicine and colleagues in Germany, England and at MIT. Stem cell therapies hold vast potential for repairing organs and treating disease.

http://ift.tt/1xRaB1Q

American Spine Launches Plasma Rich Platelet Therapy and Stem Cell Therapy Treatments

The American Spine Team is pleased to announce the launch of their Plasma Rich Platelet Therapy and Stem Cell Therapy Treatments as part of their innovative Regenerative Medicine Program. American Spine is a practice on the cutting edge, committed to providing the latest, most effective, and innovative treatments for its patients.

http://ift.tt/11SH62O

Leeds youngster's family calls for more to give 'precious gift' of blood

The family of a young cancer patient have given thanks for the "precious gift" of vital blood donations he received. Joseph Mayman and his mum Sarah are backing a new drive calling for people to donate blood and help others like the four-year-old.

http://ift.tt/1Fms5Do

A gene therapy induced emphysema model and the protective role of stem cells

BACKGROUND:Chronic obstructive pulmonary disease presents with two different phenotypes: chronic bronchitis and emphysema with parenchymal destruction. Decreased expression of vascular endothelial growth factor and increased endothelial cell apoptosis are considered major factors for emphysema.

http://ift.tt/1xW0eLi

Dendritic cell reconstitution is associated with relapse-free...

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Dendritic cell reconstitution is associated with relapse-free survival and acute GVHD severity in children after allogeneic stem cell transplantation Bone Marrow Transplantation advance online publication, November 10 2014.

http://ift.tt/1v7dCJ2

Stem Cell Technologies: World Market Outlook 2013-2023 - new market research report published

... and outlooks in the US, Japan, Europe, South Korea, China, and Israel - Regulations and ethics for stem cell research and uses in medicine - Embryonic stem cells (ESCs) and induced pluripotent adult cells (IPSCs) - Haematopoietic stem cell ...

http://ift.tt/1y9Ym0e

Press release distribution, EDGAR filing, XBRL, regulatory filings

The report is available at 'www.fitchratings.com'. Additional information is available at 'www... UPCOMING DEADLINE: LEVI & KORSINSKY, LLP Reminds Investors of Class Action against Retrophin, Inc. and Its Board of Directors and a Lead Plaintiff Deadline of December 19, 2014 )--Levi & Korsinsky announces that a class action lawsuit has been commenced in the U.S. District Court for the Southern District of N.Y. on behalf of investors who purchase... )--Fitch Ratings has published a report on Anaheim Public Financing Authority, CA.

http://ift.tt/1uSJSB1

Press release distribution, EDGAR filing, XBRL, regulatory filings

Fitch has also upgraded MTOR... BET News to Air an All-New Special "Justice for Ferguson: A Community Reacts" about the Socially-Charged Community of Ferguson, Missouri Premiering Wednesday, November 26 at 10:30 PM ET/PT On BET )--BET News reports from the ground on events unfolding in Ferguson, Missouri where the tension has been mounting with anticipation of the grand jury's decision on whether o... )--International law firm Dorsey & Whitney LLP announced today that it has named 15 new partners in the Firm, effective January 1, 2015. )--Just in time for the holidays, VINCI Education is launching a new virtual school for toddlers & preschoolers.

http://ift.tt/15hWacz

City of Hope Researchers Unlock the Potential of the Immune System to Fight Cancer

If a patient's immune system could be sufficiently bolstered, it could ultimately be a powerful weapon against blood cancers and other diseases. That approach, known widely as immunotherapy, is much more than a narrow field of study at City of Hope.

http://ift.tt/1tqtNgF

Five scientists nab awards for high-risk, high-return research

The NIH has announced that Sean Wu will receive a Pioneer Award; Michael Bassik will receive a New Innovator Award; and David Chan, Michael Angelo and Eric Nelson will receive Early Independence Awards. Five scientists at the School of Medicine have received awards totaling $7.75 million to pursue high-risk, high-reward research, the National Institutes of Health announced today.

http://ift.tt/1s5cd6J

Press release distribution, EDGAR filing, XBRL, regulatory filings

The report is available at 'www.fitchratings.com'. Additional information is availabl... )--City of Hope physicians and scientists at the Hematologic Malignancies and Stem Cell Transplantation Institute are using T cell therapy against blood cancers and ot... )--Fitch Ratings has affirmed Meritor Inc.'s Issuer Default Rating at 'B' and its senior secured credit facility rating at 'BB/RR1'.

http://ift.tt/11QXssA

Press release distribution, EDGAR filing, XBRL, regulatory filings

The report is available at 'www.fitchratings.com'. Additional information is available at 'www... UPCOMING DEADLINE: LEVI & KORSINSKY, LLP Reminds Investors of Class Action against Retrophin, Inc. and Its Board of Directors and a Lead Plaintiff Deadline of December 19, 2014 )--Levi & Korsinsky announces that a class action lawsuit has been commenced in the U.S. District Court for the Southern District of N.Y. on behalf of investors who purchase... )--Fitch Ratings has published a report on Anaheim Public Financing Authority, CA.

http://ift.tt/1yOtoJf

Press release distribution, EDGAR filing, XBRL, regulatory filings

The report is available at 'www.fitchratings.com'. Additional information is available at 'www... UPCOMING DEADLINE: LEVI & KORSINSKY, LLP Reminds Investors of Class Action against Retrophin, Inc. and Its Board of Directors and a Lead Plaintiff Deadline of December 19, 2014 )--Levi & Korsinsky announces that a class action lawsuit has been commenced in the U.S. District Court for the Southern District of N.Y. on behalf of investors who purchase... )--Fitch Ratings has published a report on Anaheim Public Financing Authority, CA.

http://ift.tt/1v5VwqO

Press release distribution, EDGAR filing, XBRL, regulatory filings

SHAREHOLDER ALERT: Brower Piven Launches An Investigation Into The Proposed Sale Of Prosensa Holding N.V. And Encourages Investors To Contact The Firm For Additional Information )--The securities litigation law firm of Brower Piven, A Professional Corporation, has commenced an investigation into possible breaches of fiduciary duty and other vi... )--Standard Tolling Corp. announces that on November 20, 2014, the Company's shareholde... )--To answer the healthcare industry's demand for better point-of-care diagnostics, Thermo Fisher Scientific Inc. and Samsung Electronics Co., Ltd. have formed ... )--Fitch Ratings has upgraded three classes of notes issued by MWAM CBO 2001-1, Ltd./Inc. as follows: --$3,813,181 class B notes to 'AAAsf' from 'Asf'; Outlook... )--Cousins Properties Incorporated announced today that it has been selected by Genuine Parts Company to develop a 150,000 square ... (more)

http://ift.tt/15hfyGI

Press release distribution, EDGAR filing, XBRL, regulatory filings

The report is available at 'www.fitchratings.com'. Additional information is availabl... )--City of Hope physicians and scientists at the Hematologic Malignancies and Stem Cell Transplantation Institute are using T cell therapy against blood cancers and ot... )--Fitch Ratings has affirmed Meritor Inc.'s Issuer Default Rating at 'B' and its senior secured credit facility rating at 'BB/RR1'.

http://ift.tt/15h9nlZ

City of Hope Researchers Unlock the Potential of the Immune System to Fight Cancer

Physicians and scientists at the Hematologic Malignancies and Stem Cell Transplantation Institute are using T cell therapy against blood cancers and other diseases )--If a patient's immune system could be sufficiently bolstered, it could ultimately be a powerful weapon against blood cancers and other diseases. That approach, known widely as immunotherapy, is much more than a narrow field of study at City of Hope.

http://ift.tt/1Fl70cB

San Antonio is a sleeping giant for innovative research, Stem Cell Summit organizers say

Genetics Policy Institute founder Bernard Siegel says global leaders will see firsthand the San Antonio is having in regenerative medicine. San Antonio may not be top of mind when world leaders think of the major centers for stem cell research and regenerative medicine, but that's about to change as the Alamo City hosts its first World Stem Cell Summit next week.

http://ift.tt/15gZhRU

Ocata Therapeutics Receives Advanced Therapy Medicinal Product...

Ocata Therapeutics, Inc., today announced that it has been granted Advanced Therapy Medicinal Product designation for its RPE therapy for macular degeneration. This designation is an essential step in allowing companies to commercialize products effectively across the European Union.

http://ift.tt/1rkv3SC

Okyanos Adopts WAL/ body-jet eco for Use in Cell Therapy

Patient recovery time boosted by use of less-invasive water-assisted device for harvesting of adipose-derived adult stem cells The body-jet eco was used during our first stem cell procedure and performed flawlessly as expected and we feel it meets our tough standards -- Dr. Todd Malan, Okyanos Okyanos , the leader in cell therapy, announced the adoption of body-jet eco for use in the harvesting of adult stem cells for use in cell therapy. The Okyanos procedure begins with the extraction of a small amount of body fat, a process done using advanced water-jet assisted liposuction technology.

http://ift.tt/1rkv2xX

New Market Report: Histogen, Inc. - Medical Equipment - Deals and Alliances Profile

The company research, develops, manufactures and sells products using the proteins and growth factors manufactured by hypoxia-induced multipotent cells for therapeutic and biomedical applications. Its products include an insoluble human extracellular matrix and a soluble complex of proteins.

http://ift.tt/1rkv0Gp

Cesca Therapeutics Announces Filing Of U.S. Pivotal IDE Application...

Cesca Therapeutics Inc. , an autologous cell-based regenerative medicine company developing proprietary devices and methods for cardiovascular, orthopedic and hematological/oncological procedures, today announced it has submitted an investigational device exemption application to the U.S. Food and Drug Administration for a pivotal multicenter study of the Company's SurgWerks-CLI and VXP System for treating advanced stages of no-option lower limb critical limb ischemia. The IDE application is the result of two prior positive pilot and feasibility studies conducted in Italy and India, respectively, and collaborative pre-IDE feedback from the U.S. FDA.

http://ift.tt/1AIVMAP

Scientists grow human pain in a dish

Researchers say they have generated the human nerve cells that normally send painful stimuli to the brain by re-programming ordinary skin cells. Photo / Thinkstock Scientists have created a miniature model of human pain, in the form of nerve cells growing in a laboratory dish that respond to the discomfort of hot chillies and other kinds of physical distress.

http://ift.tt/1AITwtg

UCLA researchers identify protein key to the development of blood stem cells

Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research , UCLA scientists have discovered a protein that is integral to the self-replication of hematopoietic stem cells during human development. The discovery lays the groundwork for researchers to generate hematopoietic stem cells in the lab that better mirror those that develop in their natural environment.

http://ift.tt/1uxGN44

Scientists convert human skin cells into sensory neurons

A team led by scientists from The Scripps Research Institute has found a simple method to convert human skin cells into the specialized neurons that detect pain, itch, touch and other bodily sensations. These neurons are also affected by spinal cord injury and involved in Friedreich's ataxia, a devastating and currently incurable neurodegenerative disease that largely strikes children.

http://ift.tt/1C63dn4

New treatments for cancer, diabetes, and heart disease-you may have a pig to thank

Genetically engineered pigs, minipigs, and microminipigs are valuable tools for biomedical research, as their lifespan, anatomy, physiology, genetic make-up, and disease mechanisms are more similar to humans than the rodent models typically used in drug discovery research. A Comprehensive Review article entitled "Current Progress of Genetically Engineered Pig Models for Biomedical Research," describing advances in techniques to create and use pig models and their impact on the development of novel drugs and cell and gene therapies, is published in BioResearch Open Access .

http://ift.tt/1r22L4J

Pain in a dish: Researchers turn skin cells into pain sensing neurons

Human noxious stimulus detecting sensory neurons produced by converting skin cells with a set of five genes to this new fate -- enabling study of 'pain' in a dish. Credit: Liz Buttermore After more than six years of intensive effort, and repeated failures that made the quest at times seem futile, Harvard Stem Cell Institute researchers at Boston Children's Hospital and Harvard's Department of Stem Cell and Regenerative Biology have successfully converted mouse and human skin cells into pain sensing neurons that respond to a number of stimuli that cause acute and inflammatory pain.

http://ift.tt/1zkHFNY

BioRestorative Therapies, Inc. Schedules Pre-IND Meeting With FDA

Company Submits Pre-IND Package for brtxDISCa Clinical Development Meeting with FDA JUPITER, Fla.-- --BioRestorative Therapies, Inc. , a life sciences company focused on adult stem cell-based therapies for various personal medical applications, announced that a Pre-IND meeting with the Center for Biologics Evaluation and Research of the U.S. Food and Drug Administration has been scheduled for December 19, 2014. The purpose of the meeting is to obtain FDA's input regarding BRT's plans for the development of brtxDISCa , the Company's novel autologous stem cell product for the treatment of chronic lumbar disc disease .

http://ift.tt/1zlGTjB

UCLA Researchers Unlock Protein Key to Harnessing Regenerative Power of Blood Stem Cells

In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member, Dr. John Chute, UCLA scientists have for the first time identified a unique protein that plays a key role in regulating blood stem cell replication in humans. This discovery lays the groundwork for a better understanding of how this protein controls blood stem cell growth and regeneration, and could lead to the development of more effective therapies for a wide range of blood diseases and cancers.

http://ift.tt/15fSYOJ

Family of paralysed cyclist make plea for help in writing book

A YOUNG man left paralysed after a cycling accident is hoping to write a book about his own experiences to help others in the same position. Dan Black, 27, of Llanfair Discoed, was in a crash with a car as he cycled to work at Chepstow Tesco on the A48 on December 2, 2009, where he worked on the fish counter.

http://ift.tt/1AIlghL

Ocata Therapeutics Receives Advanced The ...

Ocata Therapeutics, Inc., today announced that it has been granted Advanced Therapy Medicinal Product designation for its RPE therapy for macular degeneration. This designation is an essential step in allowing companies to commercialize products effectively across the European Union.

http://ift.tt/1AIlhlP

Interest rises in stem cell industry

The Maryland Stem Cell Research Commission announced that it received 240 letters of intent in response to four official requests for applications for the fiscal year 2015 funding cycle. A record 16 companies applied for funding, and the letters of intent rose by 45 over the previous year.

http://ift.tt/1AI6yXS

Eight MD Anderson faculty named as AAAS fellows

Their responsibilities may range from exploring the intricacies of biostatistics to bringing new drugs more rapidly to the patient, but eight faculty members from The University of Texas MD Anderson Cancer Center all share one honor - being named as Fellows by the American Association for the Advancement of Science. The Fellows selected to receive this highly recognized honor include Ronald DePinho, M.D., Burton F. Dickey, M.D., Varsha Gandhi, Ph.D., John Mendelsohn, M.D., Jeff Molldrem, M.D., David Piwnica-Worms, M.D., Ph.D., Sanjay Shete, Ph.D, and Stephen Ullrich, Ph.D. "It is indeed a tremendous accomplishment to be selected as an AAAS Fellow," said Ethan Dmitrovsky, M.D., provost and executive vice president at MD Anderson.

http://ift.tt/1y8i2Bx

Nail Stem Cells Prove More Versatile Than Press Ons, University of Southern California Study

Nail Stem Cells Prove More Versatile Than Press Ons There are plenty of body parts that don't grow back when you lose them. Nails are an exception, and a new study published in The Proceedings of the National Academy of Sciences reveals some of the reasons why.

http://ift.tt/1zRRnIk

Eight MD Anderson Faculty Named as AAAS Fellows

Their responsibilities may range from exploring the intricacies of biostatistics to bringing new drugs more rapidly to the patient, but eight faculty members from The University of Texas MD Anderson Cancer Center all share one honor - being named as Fellows by the American Association for the Advancement of Science. "It is indeed a tremendous accomplishment to be selected as an AAAS Fellow," said Ethan Dmitrovsky, M.D. , provost and executive vice president at MD Anderson.

http://ift.tt/1y8oU1I

Pain in a dish

This image shows human noxious stimulus detecting sensory neurons produced by converting skin cells with a set of five genes to this new fate -- enabling study of 'pain' in... After more than six years of intensive effort, and repeated failures that made the quest at times seem futile, Harvard Stem Cell Institute researchers at Boston Children's Hospital and Harvard's Department of Stem Cell and Regenerative Biology have successfully converted mouse and human skin cells into pain sensing neurons that respond to a number of stimuli that cause acute and inflammatory pain.

http://ift.tt/11Pibgw

Maryland Stem Cell Commission sees boom in interest for $10.4M in research grants

Maryland Stem Cell Research Commission expects a record number of applications for the $10.4 million it gives out annually for stem cell research.

http://ift.tt/1xtc2zA

Maryland Stem Cell Commission sees boom in interest for $10.4M in research grants

The Maryland Stem Cell Research Commission expects a record number of applications for the $10.4 million it gives out annually for stem cell research. Maryland Stem Cell Research Commission expects a record number of applications for the $10.4 million it gives out annually for stem cell research.

http://ift.tt/1xtc3DD

Could nails help us regrow LIMBS? Stem cells found on fingers and...

'You must have known': Woman who claims she had an affair with millionaire hedge fund owner confronts his WIFE on Twitter with photo of a handwritten note 'from him' 'The cops know what they're doing, he doesn't': Angry father hits out after his 12-year-old son was shot dead by police after he was spotted with a BB gun 'If we left, they wouldn't have nobody': Heroic janitor and cook recall how they cared for elderly patients after shut care home was abandoned by staff Who bares, wins! Jennifer Lopez, 45, reveals her toned stomach in bold wrap dress as stars gather for the American Music Awards Suspect who confessed to kidnapping six-year-old Etan Patz in 1979 to learn whether his confession can be used at a murder trial Don't bother counting calories... it's the type of food that matters: Items high in fat may actually be good at keeping the weight off Cops gave 16-year-old driver who ... (more)

http://ift.tt/1FjOvFk

Family of paralysed cyclist plea for help in writing book

MM 28.3.10 STORY DAVID DEANS DAN BLACK PARALYSED AFTER AN CAR COLLIDED WITH HIM AT ROOKWOOD HOSPITAL CARDIFF PICTURED WITH HIS MOTHER MICHELA A YOUNG man left paralysed after a cycling accident is hoping to write a book about his own experiences to help others in the same position. Dan Black, 27, of Llanfair Discoed, was in a crash with a car as he cycled to work at Chepstow Tesco on the A48 on December 2, 2009, where he worked on the fish counter.

http://ift.tt/1xMwe3n

Family of paralysed cyclist plea for help in writing book

MM 28.3.10 STORY DAVID DEANS DAN BLACK PARALYSED AFTER AN CAR COLLIDED WITH HIM AT ROOKWOOD HOSPITAL CARDIFF PICTURED WITH HIS MOTHER MICHELA A YOUNG man left paralysed after a cycling accident is hoping to write a book about his own experiences to help others in the same position. Dan Black, 27, of Llanfair Discoed, was in a crash with a car as he cycled to work at Chepstow Tesco on the A48 on December 2, 2009, where he worked on the fish counter.

http://ift.tt/1xMwdMG

Press release distribution, EDGAR filing, XBRL, regulatory filings

CAT-1004, a NF-KB inhibitor, is expected to enter a Phase 2 clinical trial in th... )--Medidata , the leading global provider of cloud-based solutions for clinical research in life sciences, today announced that it will host a financial analyst... )--Rambus Inc. today announced that its Cryptography Research division has licensed select security-related technologies to Cisco Systems.

http://ift.tt/1pfgQdU

Could you save life of teen battling cancer?

Cwmbran teen Emily Clark desperately needs a bone marrow transplant after being told her cancer has returned. Could you be a hero for Emily? APPEAL: Emily Clark, from Cwmbran, needs a bone marrow transplant after she was last week dealt the news that her cancer, Non-Hodgkin Lymphoma, had returned TODAY, we're asking you to help in the battle to save the life of a 17-year-old girl battling cancer.

http://ift.tt/1pf3QVO

RMSR Certification: Newly Released Video Shows Entry Level Candidates ...

... Brain Scanning Genetics Genetic Engineering Gene Splicing Therapeutic Proteins Monoclonal Antibodies Stem Cell Research Transplants, Prosthetics, & Implants Joint Replacements Prosthetic Limbs Implantable Nerve Stimulators Advances in Eye Surgery ...

http://ift.tt/1peULMw

New Stem Cell Treatment Found To Cure 'Bubble...

A new stem cell gene therapy developed by researchers at UCLA is set to begin clinical trials early next year after the technique reportedly cured 18 children who were born without working immune systems due to a condition known as ADA-deficient Severe Combined Immunodeficiency or "Bubble Baby" disease. The treatment was developed by Dr. Donald Kohn, a member of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, and his colleagues, and according to the university, it is able to identify and correct faulty genes by using the DNA of the youngsters born with this life-threatening condition.

http://ift.tt/1vEMgNU

Potential to repair injured adult brains by reprogramming 'support cells' into neurons

The portion of the adult brain responsible for complex thought, known as the cerebral cortex, lacks the ability to replace neurons that die as a result of Alzheimer's disease , stroke , and other devastating diseases. A study in the International Society for Stem Cell Research's journal Stem Cell Reports , published by Cell Press shows that a Sox2 protein, alone or in combination with another protein, Ascl1, can cause nonneuronal cells, called NG2 glia, to turn into neurons in the injured cerebral cortex of adult mice.

http://ift.tt/1zj99mV

Principles of regulatory information conservation between mouse and human.

To broaden our understanding of the evolution of gene regulation mechanisms, we generated occupancy profiles for 34 orthologous transcription factors in human-mouse erythroid progenitor, lymphoblast and embryonic stem-cell lines. By combining the genome-wide transcription factor occupancy repertoires, associated epigenetic signals, and co-association patterns, here we deduce several evolutionary principles of gene regulatory features operating since the mouse and human lineages diverged.

http://ift.tt/1v2h4V8

Want Blue Eyes With That Baby?By Eleanor Clift

Should a woman's own 55-year-old mother bear the woman's triplets? Well, it's happening. Where should society draw the lines here? Welcome to the brave new world of technology-enhanced human reproduction with its promise of alleviating the heartache of infertility, and its dangers of crossing ethical and moral lines.

http://ift.tt/1AGip93

Bikers flock to Sunflower fundraiser

Whether it is because community commitment among mainstream motorcycle clubs is so strong, or because riders have a permanent chip on their shoulders about being seen as noisy, antisocial misfits, or whether we just can't resist a good party, nobody knows. But the hard-working, permanently cash-strapped volunteers of the Sunflower Fund, who need R2000 to process each candidate for the South African Bone Marrow Registry and who depend entirely of corporate and public donations to get it, are very glad that it is so.

http://ift.tt/1uvEnmw

Could you save life of teen battling leukaemia?

Cwmbran teen Emily Clark desperately needs a bone marrow transplant after being told her leukaemia has returned. Could you be a hero for Emily? APPEAL: Emily Clark, from Cwmbran, needs a bone marrow transplant after she was last week dealt the news that her cancer, Non-Hodgkin Lymphoma, had returned TODAY, we're asking you to help in the battle to save the life of a 17-year-old girl battling leukaemia.

http://ift.tt/15d1fCR

Surprise finding has implications for wound repair therapies and inhibiting cancer

While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments. Karl Willert, PhD, assistant professor in the Department of Cellular and Molecular Medicine, and colleagues were attempting to use induced pluripotent stem cells to create a "disease-in-a-dish" model for focal dermal hypoplasia , a rare inherited disorder caused by mutations in a gene called PORCN.

http://ift.tt/1v23DEG

In the fight against cancer, new understanding of genetic replication could help

A new line of research from a team at Florida State University is pushing the limits on what the world knows about how human genetic material is replicated and what that means for people with diseases where the replication process is disrupted, such as cancer . The team, lead by Department of Biological Sciences Professor David Gilbert and post-doctoral researcher Ben Pope, has taken an in-depth look at how DNA and the associated genetic material replicate and organize within a cell's nucleus.

http://ift.tt/1v23Asz

Could you save life of teen battling leukaemia?

Cwmbran teen Emily Clark desperately needs a bone marrow transplant after being told her leukaemia has returned. Could you be a hero for Emily? APPEAL: Emily Clark, from Cwmbran, needs a bone marrow transplant after she was last week dealt the news that her cancer, Non-Hodgkin Lymphoma, had returned TODAY, we're asking you to help in the battle to save the life of a 17-year-old girl battling leukaemia.

http://ift.tt/1xT8TOE

Be a hero for Emily - help save her life

TODAY, we're asking you to help in the battle to save the life of a 17-year-old girl battling leukaemia. Emily Clark, from Cwmbran, needs a bone marrow transplant after she was last week dealt the terrible news that her cancer, Non Hodgkin Lymphoma, had returned.

http://ift.tt/1xqOQlu

Parkinson's drug treatments industry forecast to total US$3.5Bn by end of 2018

Analysts forecast the overall market for Parkinsons disease therapies will grow steadily to 2024. Rising disease prevalence, due to ageing populations, stimulates that market.

http://ift.tt/1AF7D2P

Signaling Molecule Crucial to Stem Cell Reprogramming

While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments. Karl Willert, PhD, assistant professor in the Department of Cellular and Molecular Medicine, and colleagues were attempting to use induced pluripotent stem cells to create a "disease-in-a-dish" model for focal dermal hypoplasia , a rare inherited disorder caused by mutations in a gene called PORCN.

http://ift.tt/1zhrJvL

UC San Diego Raises $148.3 Million in Private Support

The University of California, San Diego recognized as one of the top 15 research universities worldwide raised $148.3 million in private support in fiscal year 2013-2014. Nearly 30,000 donors helped to fund UC San Diego's strategic plan commitment to being a student-centered, research-focused, service-oriented public institution that provides opportunity for all.

http://ift.tt/1vDKBHM

Wnt Pathway Regulation of Embryonic Stem Cell Self-Renewal

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. A new type of review journal, featuring comprehensive collections of expert review articles on important topics in the molecular life sciences CiteULike organises scholarly papers or literature and provides bibliographic for universities and higher education establishments.

http://ift.tt/1xmhV1k

I2-catenin enhances Oct-4 activity and reinforces pluripotency through a TCF-independent mechanism.

Cell stem cell , Vol. 8, No. 2. , pp. 214-227, doi:10.1016/j.stem.2010.12.010 To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.

http://ift.tt/1vcKcdU

Type 2 Diabetes Insulin Use Reduced With Bone Marrow Stem Cell Transplants

Research reveals that individuals with type 2 diabetes who received self-donated bone marrow stem cell transplants needed less insulin following the transplants, in comparison to a control group of individuals with type 2 diabetes who didn't receive transplants. While there's growing interest in the use of stem cell transplantation for treating type 2 diabetes, not much research has looked at the use of stem cells derived from bone marrow.

http://ift.tt/1uUXj1G

Brave grandmother Diane Harrison bows out of fundraising as her cancer spreads

A BRAVE grandmother who outlived a doctor's cancer prognosis and dedicated herself to raising funds to help send a disabled relative to China has said she will not be able to organise any more events because the disease is spreading. Diane Harrison, 55, of Horton Bank Top , Bradford, with the help of family and friends, helped organise a fashion show which made more than A 800 to get her cousin's husband Stan Padley to Beijing in January for stem-cell treatment designed to restore his voice and help him eat again.

http://ift.tt/1qN6nrc

MS sufferer's family starts appeal

A WOMAN with multiple sclerosis is bidding to become the first Scottish patient to undergo cutting-edge stem cell treatment in a Russian clinic. A WOMAN with multiple sclerosis is bidding to become the first Scottish patient to undergo cutting-edge stem cell treatment in a Russian clinic.

http://ift.tt/1xLSg7t?

Five scientists nab awards for high-risk, high-return research

The NIH has announced that Sean Wu will receive a Pioneer Award; Michael Bassik will receive a New Innovator Award; and David Chan, Michael Angelo and Eric Nelson will receive Early Independence Awards. Five scientists at the School of Medicine have received awards totaling $7.75 million to pursue high-risk, high-reward research, the National Institutes of Health announced today.

http://ift.tt/1s5cd6J

Battling Multiple Myeloma

One of the most common drugs to fight the blood cancer, multiple myeloma, causes patients' platelets to decrease. Low platelet count means delaying treatment or lower doses of the drug.

http://ift.tt/1r6SI93

Bionomics Limited Release: BNC101 Data To Be Presented At

Bionomics Limited is presenting a poster on cancer stem cell antibody BNC101 at the 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Barcelona. The four day symposium attracts approximately 2,000 academics, scientists and pharmaceutical industry professionals from around the world.

http://ift.tt/1r6mavW

Nail stem cells prove more versatile than press ons

There are plenty of body parts that don't grow back when you lose them. Nails are an exception, and a new study reveals some of the reasons why.

http://ift.tt/14YPrEi

Health Science Center to educate public on stem cells in advance of World Stem Cell Summit

File photo of University of Texas Health Science Center at San Antonio's Dr. William Henrich. The university will host a free public education session on stem cell research and regenerative medicine on Dec. 2. The University of Texas Health Science Center at San Antonio is teaming up with promoters of the 2014 World Stem Cell Summit to offer a special public education day in advance of the three-day conference, slated for Dec. 3-5.

http://ift.tt/1xWzkRb

Health Science Center to educate public on stem cells in advance of World Stem Cell Summit

... 3-5. The informational event is scheduled for Dec. 2 at the Health Science Center and will focus on stem cell research and regenerative medicine. The event is free and open to the public. The Health Science Center is an organizing sponsor of ...

http://ift.tt/1AtJr3c

University of Pennsylvania Doses First Patient In Phase IIa Clinical...

University of Pennsylvania Doses First Patient In Phase IIa Clinical Trial Using CardioCell 's Stem Cell Therapy To Treat Chronic Heart Failure Due To Non-Ischemic Cardiomyopathy The Only Chronic HF Clinical Trial Using Ischemia-Tolerant Mesenchymal Stem Cells Continues Recruitment at Emory University, Northwestern University and the University of Pennsylvania PHILADELPHIA-- --CardioCell LLC, a Stemedica Cell Technologies Inc. subsidiary that creates allogeneic stem-cell therapies for cardiovascular indications, announces the treatment of its first patient in the University of Pennsylvania's Phase IIa clinical trial for chronic heart failure of non-ischemic cardiomyopathy.

http://ift.tt/1xZtdwl

Cellular Origin of Fibrosis

Harvard Stem Cell Institute scientists at Brigham and Women's Hospital say they have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions. The buildup of scar tissue, known as fibrosis, has a number of consequences, including inflammation and reduced blood and oxygen delivery to the organ.

http://ift.tt/1qHO9aw

Dynamic signaling network for the specification of embryonic pancreas and liver progenitors.

Science , Vol. 324, No. 5935. , pp. 1707-1710, doi:10.1126/science.1174497 To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.

http://ift.tt/1xWbtRv

HIV/AIDS Drugs Could Be Repurposed to Treat Age-Related Macular Degeneration

A landmark study published today in the journal Science by an international group of scientists, led by the laboratory of Dr. Jayakrishna Ambati, professor and vice chair of the Department of Ophthalmology & Visual Sciences at the University of Kentucky, reports that HIV/AIDS drugs that have been used for the last 30 years could be repurposed to treat age-related macular degeneration , as well as other inflammatory disorders, because of a previously undiscovered intrinsic and inflammatory activity those drugs possess. AMD is a progressive condition that is untreatable in up to 90 percent of patients and is a leading cause of blindness in the elderly worldwide.

http://ift.tt/1xWbtAX

Amateur photographers aid in remote skin sore trial

A quality control check by a medical photographer deemed 97 per cent of the unmodified images were adequate for interpretation while digital storing each image in triplicate resulted in just 0.17 per cent of images being unavailable for outcome assessment. Credit: Dr Asha Bowen Paediatric infectious disease specialists are bringing novel skin sore research methods to WA in the form of a protocol allowing non-professional photographers to capture high-quality images of skin sores for use in treatment trials.

http://ift.tt/1xb6hWX

HIV drugs show promise in treating common eye disease

A class of drugs used for three decades by people infected with the virus that causes AIDS may be effective in treating a leading cause of blindness among the elderly. HIV drugs called nucleoside reverse transcriptase inhibitors , including AZT and three others, blocked age-related macular degeneration in mice and worked well in experiments involving human retinal cells in the laboratory, researchers said on Thursday.

http://ift.tt/1F8ABWw

Kalorama: Stem Cell Therapies Hold Hope for Alzheimer's Treatments

Even though the disease and the course of treatment is not well understood, there are several developers tackling this area of stem cell therapy and the promise it holds in treating, or perhaps even curing, Alzheimer's disease. Kalorama Information believes that given this potential there is an opportunity for a future market.

http://ift.tt/1r4DxgC

Nail stem cells prove more versatile than press ons

There are plenty of body parts that don't grow back when you lose them. Nails are an exception, and a new study published in the Proceedings of the National Academy of Sciences reveals some of the reasons why.

http://ift.tt/1z2L7ws

Researchers characterize a protein mutation that alters tissue development in males before birth

Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges. The discovery marks the latest in a series of findings related to the protein SRY , which serves as a master switch for ensuring typical human male maturation.

http://ift.tt/1v1OV1T

Delivering stem cells into heart muscle may enhance cardiac repair and reverse injury

Delivering stem cell factor directly into damaged heart muscle after a heart attack may help repair and regenerate injured tissue, according to a study led by researchers from Icahn School of Medicine at Mount Sinai presented at the American Heart Association Scientific Sessions 2014 in Chicago, IL. "Our discoveries offer insight into the power of stem cells to regenerate damaged muscle after a heart attack," says lead study author Kenneth Fish, PhD, Director of the Cardiology Laboratory for Translational Research, Cardiovascular Research Center, Mount Sinai Heart, Icahn School of Medicine at Mount Sinai.

http://ift.tt/1zIZ7MS

SRY protein alters specific gender-related tissue in males before birth

Case Western Reserve researchers have identified a protein mutation that alters specific gender-related tissue in males before birth and can contribute to the development of cancer as well as other less life-threatening challenges. The discovery marks the latest in a series of findings related to the protein SRY , which serves as a master switch for ensuring typical human male maturation.

http://ift.tt/1HtZNed

Be The Match Walk and Run on Saturday to benefit marrow transplant research

A Be The Match Walk and Run will have transplant patients, donors and the community on a fundraising mission to save lives. The Tot Trot, 5K and 1K will respectively start at 8:15, 8:30 and 8:40 a.m. Saturday at Shoreline Aquatic Park, 200 Aquarium Way.

http://ift.tt/1xwoBxM

University of Louisville receives $50,000 grant for childhood cancer research

The St. Baldrick's Foundation, a volunteer-driven and donor-centered charity dedicated to raising money for childhood cancer research, has awarded a one-year, $50,000 grant to the University of Louisville . This grant is one of 40 infrastructure grants awarded as part of the foundation's fall grant cycle, totaling more than $2.5 million and surpassing last year's total awarded during this same period.

http://ift.tt/1F6UxZS

ViaCyte, Inc. (Formerly Known as Novocell, Inc.) To Present At 26th...

A Phase 1/2 trial to assess safety, tolerability, and efficacy of the product in human subjects with diabetes was launched in The presentation will be webcast live at the aforementioned time, and archived for viewing 90 days thereafter, via the Company's website at www.viacyte.com , under the News and Events Section. About ViaCyte ViaCyte is a privately-held regenerative medicine company focused on developing a novel cell therapy for the treatment of diabetes.

http://ift.tt/14SDNuu

Delivery of stem cells into heart muscle after heart attack may...

Delivering stem cell factor directly into damaged heart muscle after a heart attack may help repair and regenerate injured tissue. A novel SCF gene transfer delivery system induced the recruitment and expansion of adult c-Kit positive cardiac stem cells to injury sites that reversed heart attack damage in a pre-clinical model.

http://ift.tt/1x6mbSB

Historic Rogers family donation leads to creation of new Toronto heart disease research centre

Dr. Michael Apkon, president and CEO of Sick Kids, speaks Thursday at the announcement of a $130 million donation by the family of late media mogul Ted Rogers to fund a research centre in his name. The Hospital for Sick Children, University Health Network and the University of Toronto have jointly announced the creation of a new centre for heart disease research, thanks to the biggest single donation in Canadian health care history.

http://ift.tt/1yYqKjY

Pluripotent cells created by nuclear transfer can prompt immune reaction, researchers find

Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell's mitochondria, according to a study in mice. Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell's mitochondria, according to a study in mice by researchers at the Stanford University School of Medicine and colleagues in Germany, England and at MIT.

http://ift.tt/1uYiAZT

Cellular origin of fibrosis found

The cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions has been found by researchers. The buildup of scar tissue is known as fibrosis.

http://ift.tt/1uYiAZL

Signaling molecule crucial to stem cell reprogramming

While investigating a rare genetic disorder, researchers have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments. While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments.

http://ift.tt/1yYqK3p

Stem Cells Translational Medicine Release: Fat And Bone...

... significantly advancing the clinical utilization of stem cell molecular and cellular biology. By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices. ...

http://ift.tt/1xX9y02

HIV drugs show promise in treating common eye disease

A class of drugs used for three decades by people infected with the virus that causes AIDS may be effective in treating a leading cause of blindness among the elderly. HIV drugs called nucleoside reverse transcriptase inhibitors , including AZT and three others, blocked age-related macular degeneration in mice and worked well in experiments involving human retinal cells in the laboratory, researchers said on Thursday.

http://ift.tt/1uY7nZ5

Three brothers with rare neurological disorder raise awareness about debilitating disease

... Center from their Orange County home twice a year for check-ups, and the brothers are taking part in stem cell research. Weight training and keeping a healthy diet also helps with their balance issues. They also take medicines to curb tremors. "I ...

http://ift.tt/1uY7pQK

Pluripotent cells created by nuclear transfer can prompt immune reaction, researchers find

Stanford researchers find that genetic differences in mitochondria contained in egg cells used in a process known as nuclear transfer can prompt rejection by the immune system in mice. Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell's mitochondria, according to a study in mice by researchers at the S tanford University School of Medicine and colleagues in Germany, England and at MIT.

http://ift.tt/1vtcxha

UCLA stem cell researcher pioneers gene therapy cure for children with 'Bubble Baby' disease

Christian and Alysia Padilla-Vaccaro and their twins, Annabella and Evangelina. With a newly restored immune system, Evangelina lives a normal and healthy life.

http://ift.tt/1uXZjHR

Heart research centre to be built with $239M in funding from Rogers family, hospitals

... The centre will bring together research, education and innovation in individualized genomic medicine, stem cell research, bioengineering, and cardiovascular treatment and management. The family of late media mogul Ted Rogers has donated $130 million ...

http://ift.tt/14RYqqD?

HIV/AIDS drugs could be repurposed to treat AMD

The back of the eye with late stage AMD. Credit: Bradley D. Gelfand, University of Kentucky Department of Ophthalmology and Visual Sciences A landmark study published today in the journal Science by an international group of scientists, led by the laboratory of Dr. Jayakrishna Ambati, professor & vice chair of the Department of Ophthalmology & Visual Sciences at the University of Kentucky, reports that HIV/AIDS drugs that have been used for the last 30 years could be repurposed to treat age-related macular degeneration , as well as other inflammatory disorders, because of a previously undiscovered intrinsic and inflammatory activity those drugs possess.

http://ift.tt/1p3mQq8

An Ebola virus protein can cause massive inflammation and leaky blood vessels

Ebola GP protein covers the virus' surface and is shed from infected cells during infection. A study published on November 20th in PLOS Pathogens reports that shed GP can trigger massive dysregulation of the immune response and affect the permeability of blood vessels Ebola virus has seven genes.

http://ift.tt/1p3mQ9y

Weight and eating habits in Parkinson's disease

Patients affected by Parkinson's disease often show marked changes in body weight: they may gain or lose a lot of weight depending on the stage of the disease, or they may put on up to ten kilos after deep brain stimulation . This situation considerably worsens the quality of life of a person who is already suffering from heavily disabling motor disorders, so it is important to understand what are the factors that cause it.

http://ift.tt/1yXOFAc

Mount Sinai Researchers Awarded $1 Million Grant to Find New Stem...

November 20, 2014 - The National Eye Institute , a division of the National Institutes of Health, has awarded researchers at the Icahn School of Medicine at Mount Sinai a five-year grant that will support an effort to re-create a patient's ocular stem cells and restore vision in those blinded by corneal disease. About six million people worldwide have been blinded by burns, trauma, infection, genetic diseases, and chronic inflammation that result in corneal stem cell death and corneal scarring.

http://ift.tt/1yY3NNM

Reprogramming 'support cells' into neurons could repair injured adult brains

... of Alzheimer's disease, stroke, and other devastating diseases. A study in the International Society for Stem Cell Research's journal Stem Cell Reports , published by Cell Press on November 20 shows that a Sox2 protein, alone or in combination with ...

http://ift.tt/1uDgSvl

The cellular origin of fibrosis: Team identifies rare stem cells that ...

Rare stem cells that give rise to scar-tissue secreting myofibroblast cells, here found near the blood vessels of a mouse kidney . Credit: Rafael Kramann, M.D. Harvard Stem Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.

http://ift.tt/1uX8AQy

Mount Sinai researchers awarded grant to find new stem cell therapies for vision recovery

The National Eye Institute , a division of the National Institutes of Health, has awarded researchers at the Icahn School of Medicine at Mount Sinai a five-year grant totaling $1 million that will support an effort to re-create a patients' ocular stem cells and restore vision in those blinded by corneal disease. About six million people worldwide have been blinded by burns, trauma, infection, genetic diseases, and chronic inflammation that result in corneal stem cell death and corneal scarring.

http://ift.tt/1x5jPmT

2014 NYSCF - Robertson Stem Cell Investigators

... n is a non-profit organization dedicated to accelerating cures for the major diseases of our time through stem cell research. For more information on

http://ift.tt/14S8cJt

Rogers heart research centre created with $239M in funding from family, hospitals

... The centre will bring together research, education and innovation in individualized genomic medicine, stem cell research, bioengineering, and cardiovascular treatment and management. The centre will also establish an innovation fund to drive ...

http://ift.tt/1AoiYEm

and Now for Some Good News: 'Bubble Boy' Disease Cured With Stem ...

... even a simple cold could be fatal. But doctors at University of California Los Angeles (UCLA) Broad Stem Cell Research Center gave her a new treatment, using her own stem cells, that has essentially cured her disease. She's one of 18 children who ...

http://ift.tt/1HqLw1I

Signaling Molecule Crucial to Stem Cell Reprogramming

While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments. Karl Willert, PhD, assistant professor in the Department of Cellular and Molecular Medicine, and colleagues were attempting to use induced pluripotent stem cells to create a "disease-in-a-dish" model for focal dermal hypoplasia , a rare inherited disorder caused by mutations in a gene called PORCN.

http://ift.tt/1xGV06e

Stephanie Headley too ill for life-prolonging treatments

Ottawa resident Stephanie Headley was told in 2009 she had five years to live after she was diagnosed with a severe version of systemic scleroderma, an autoimmune disorder. An Ottawa woman with a rare auto-immune disorder has learned she's too ill to qualify for a potentially life-saving treatment in the United States.

http://ift.tt/1qAipEf

Reprogramming 'support cells' into neurons could repair injured adult brains

The portion of the adult brain responsible for complex thought, known as the cerebral cortex, lacks the ability to replace neurons that die as a result of Alzheimer's disease, stroke, and other devastating diseases. A study in the International Society for Stem Cell Research's journal Stem Cell Reports , published by Cell Press on November 20 shows that a Sox2 protein, alone or in combination with another protein, Ascl1, can cause nonneuronal cells, called NG2 glia, to turn into neurons in the injured cerebral cortex of adult mice.

http://ift.tt/1F7x2BV

Signaling molecule crucial to stem cell reprogramming

While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with significant implications for stem cell-based regenerative medicine, wound repair therapies and potential cancer treatments. Karl Willert, PhD, assistant professor in the Department of Cellular and Molecular Medicine, and colleagues were attempting to use induced pluripotent stem cells to create a "disease-in-a-dish" model for focal dermal hypoplasia , a rare inherited disorder caused by mutations in a gene called PORCN.

http://ift.tt/1F7x2Sh

The cellular origin of fibrosis

Rare stem cells that give rise to scar-tissue secreting myofibroblast cells, here found near the blood vessels of a mouse kidney . Harvard Stem Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.

http://ift.tt/1F7x5O6

Pluripotent cells created by nuclear transfer can prompt immune reaction, researchers find

Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell's mitochondria, according to a study in mice by researchers at the Stanford University School of Medicine and colleagues in Germany, England and at MIT. Stem cell therapies hold vast potential for repairing organs and treating disease.

http://ift.tt/1F7x38T

Global Cell and Tissue Analysis Products Market 2014-2018

... Pharmaceutical, Research, and CROs. It has wide-ranging applications in drug discovery and development, stem cell research, cell biology, and in other research practices. TechNavio's analysts forecast the Global Cell and Tissue Analysis Products ...

http://ift.tt/1x5hjx6

Benefunder Explores Role of Philanthropy in Fueling Innovation During World Stem Cell Summit

As part of its participation in the World Stem Cell Summit, Benefunder, a philanthropic services organization that works with wealth management firms to connect donors with leading researchers across the nation, will be hosting a panel on Patient Groups, Foundations & Venture Philanthropy- Crucial Parties Funding Research and Delivering Therapies to Market and Patients . The plenary session, which will be held on Dec. 5, 2014 , will discuss the role of these key groups, which are amongst the most misunderstood yet crucial partners in bringing promising therapies and technologies to market and patients, as well as how tech transfer offices and early stage biotech companies can more effectively partner with these organizations.

http://ift.tt/1ueYWn8

Can Salon Science AnaGain shampoo really give you longer, thicker hair in 3 months?

Can this shampoo really give you longer, thicker hair in just THREE months? Beauty brand say they can boost your barnet thanks to stem cell technology A revolutionary new haircare system has been developed which promises to give you thicker, fuller, and longer hair in just three months. The Salon Science AnaGain range, which was developed by Dr Bernhard Irrgang with the help of celebrity stylist Andrew Jose, uses stem cells from rare plant extracts - much like many face creams - to boost and build the hair.

http://ift.tt/1Hqlmwa

Historic $130 million gift from the Rogers family to establish the...

... powerful network of researchers and educators is translating exciting ideas, innovations and therapies in stem cell research and regenerative medicine into clinical settings where they will address the most challenging problems across the spectrum ...

http://ift.tt/1xWMoXG

Stem cell researcher pioneers gene therapy cure for children with 'Bubble Baby' disease

UCLA stem cell researchers have pioneered a stem cell gene therapy cure for children born with adenosine deaminase -deficient severe combined immunodeficiency , often called "Bubble Baby" disease, a life-threatening condition that if left untreated can be fatal within the first year of life. The groundbreaking treatment was developed by renowned stem cell researcher and UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Donald Kohn, whose breakthrough was developed over three decades of research to create a gene therapy that safely restores immune systems in children with ADA-deficient SCID using the patient's own cells with no side effects.

http://ift.tt/1BQjMDx