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Wednesday, February 4, 2015

Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells

Cell Reports , Vol. 10, No. 4. , pp. 537-550, doi:10.1016/j.celrep.2014.12.051 During cerebellar development, the main portion of the cerebellar plate neuroepithelium gives birth to Purkinje cells and interneurons, whereas the rhombic lip, the germinal zone at its dorsal edge, generates granule cells and cerebellar nuclei neurons.

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