mESC-Based in vitro Differentiation Models to Study Vascular Response ...

Fax: Because of high exposure to systemic noxae, vascular endothelial cells have to ensure distinct damage defense and regenerative mechanisms to guarantee vascular health. For meaningful toxicological drug assessments employing embryonic stem cell -based in vitro models, functional competence of differentiated progeny and detailed knowledge regarding damage defense mechanisms are essential.

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