Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth

E-mail: helmanl@nih.gov To identify novel signaling pathways necessary for rhabdomyosarcoma survival, we performed a loss-of-function screen using an inducible small hairpin RNA library in an alveolar and an embryonal RMS cell line.

http://www.nature.com/onc/journal/vaop/ncurrent/full/onc2012590a.html