New stem cell-based screen reveals promising drug for Lou Gehrig's disease

The c-Jun-mediated cell death pathway is activated in stem cell-derived motor neurons exposed to trophic factor withdrawal .... Amyotrophic lateral sclerosis , also called Lou Gehrig's disease, is a fatal disease that causes motor neurons, which are responsible for controlling muscles, to die.

http://www.eurekalert.org/pub_releases/2013-04/cp-nsc041113.php