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Monday, July 15, 2013

Caffeine suppresses homologous recombination through interference...

We used chemical inhibitors and genetically deficient mouse embryonic stem cell lines to study the role of DNA damage response in stable integration of the transfected DNA and found that caffeine rapidly, efficiently and reversibly inhibited homologous integration of the transfected DNA as measured by several homologous recombination-mediated ... (more)

http://nar.oxfordjournals.org/content/41/13/6475.short?rss=1

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