Pre-leukemic stem cells with both mutated and healthy copies of the RUNX1 gene already display some of the characteristics of acute myeloid leukemia.
http://medicalxpress.com/news/2013-09-leukemia-cells-addicted-healthy-gene.html
http://medicalxpress.com/news/2013-09-leukemia-cells-addicted-healthy-gene.html
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