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Friday, July 25, 2014

A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression

Although TTF-1 inhibits the epithelial-to-mesenchymal transition induced by transforming growth factor-β in lung adenocarcinoma cells, the mechanism through which TTF-1 inhibits the functions of TGF-β is unknown.

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