Genomic origin of telomere protectors discovered

Telomeric repeat-containing RNA do not originate in all telomeres that protect the 20 murine chromosomes, researchers report, but do exclusively in chromosome 18 and, to a lesser extent, in chromosome 9. This peculiarity sets the stage for future genetic manipulation in mice with the aim of researching the in vivo role of these molecules in telomere biology and in illness. RNA is one of the most primitive molecules associated with life that has awakened most interest over the last decade; a sister molecule to cellular DNA from which it originates via a process called transcription.

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