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Friday, September 26, 2014

Persistence of Virus Reservoirs in ART-Treated SHIV-Infected Rhesus...

Despite many advances in AIDS research, a cure for HIV infection remains elusive. Here, we performed autologous hematopoietic stem cell transplantation in three Simian/Human Immunodeficiency Virus -infected, antiretroviral therapy -treated rhesus macaques using HSCs collected prior to infection and compared them to three SHIV-infected, ART-treated, untransplanted control animals to assess the effect of conditioning and autologous HSCT on viral persistence.

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