The effect of standard and high-fluence corneal cross-linking (CXL) on cornea and limbus.

When treating peripheral ectatic disease-like pellucid marginal degeneration , corneal cross-linking with UV-A and riboflavin must be applied eccentrically to the periphery of the lower cornea, partly irradiating the corneal limbus. Here, we investigated the effect of standard and double-standard fluence corneal cross-linking with riboflavin and UV-A on cornea and corneal limbus in the rabbit eye in vivo.

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