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Monday, October 6, 2014

'JAKing' up blood cancers, one cell at a time

Eight months after transplantation of a single mutated cell, the bone marrow and spleen of a previously healthy mouse display a full-blown type of blood cancer characterized by... A solitary cell containing a unique abnormality can result in certain types of blood cancers known as myeloproliferative neoplasms , according to a study published in The Journal of Experimental Medicine . MPNs are rare types of cancer where the bone marrow makes too many cells that clog up the works and thicken the blood, potentially causing bleeding problems, heart attack, or even stroke.

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