'JAKing' up blood cancers, one cell at a time

Eight months after transplantation of a single mutated cell, the bone marrow and spleen of a previously healthy mouse display a full-blown type of blood cancer characterized by overproduction of blood clot-forming cells. Credit: Lundberg et al., 2014 A solitary cell containing a unique abnormality can result in certain types of blood cancers known as myeloproliferative neoplasms , according to a study published in The Journal of Experimental Medicine .

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