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Friday, January 2, 2015

Bad Luck Of Random Mutations Plays Predominant Role In Cancer, Johns...

Bad Luck Of Random Mutations Plays Predominant Role In Cancer, Study Shows Statistical modeling links cancer risk with number of stem cell divisions Scientists from the Johns Hopkins Kimmel Cancer Center have created a statistical model that measures the proportion of cancer incidence, across many tissue types, caused mainly by random mutations that occur when stem cells divide. By their measure, two-thirds of adult cancer incidence across tissues can be explained primarily by "bad luck," when these random mutations occur in genes that can drive cancer growth, while the remaining third are due to environmental factors and inherited genes.

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