Steering the epigenome to turn specific genes on

Duke University researchers have developed a new method to precisely control when genes are turned on and active: by manipulating the epigenome - the web of proteins that supports and controls gene activity and a current hot topic in cancer research. The researchers say having the ability to steer the epigenome will help them explore the roles that particular promoters and enhancers play in cell fate or the risk for genetic disease, and it could provide a new avenue for gene therapies and guiding stem cell differentiation.

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