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Monday, April 20, 2015

Sulforaphane regulates self-renewal of pancreatic cancer stem cells...

Sulforaphane , a component of dietary cruciferous vegetables has been characterized for its anti-proliferative properties. We have recently demonstrated that pancreatic CSCs display activation of sonic hedgehog pathway which are fundamental drivers of stem cell renewal, and SFN inhibits the self-renewal of pancreatic CSCs in vitro.

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