Stem Cell Roundup: 2014

Wednesday, December 31, 2014

Stem Cell Therapy Fixes Post-Surgical Airway Abnormality

Using stem cells derived from a patient's own bone marrow, researchers have repaired a fistula -- a potentially fatal tissue abnormality -- in the man's lower airway. "This is another interesting new therapeutic approach for stem cells," said lead researcher Dr. Francesco Petrella, deputy director of thoracic surgery at the European Institute of Oncology in Milan, Italy.

http://ift.tt/1BjhdWk

Fresh hope for dementia patients

A DESPERATE scramble for money could have sparked a deadly NYE stampede that killed at least 35 people and injured 42 others. WARNING: Graphic photos KIM Jong-Un says he's open to the "highest-level" talks with South Korea in an address which also called for an improvement in strained cross-border relations.

http://ift.tt/1B7kIkf

Stem Cell Therapy Fixes Post-Surgical Airway Abnormality

Using stem cells derived from a patient's own bone marrow, researchers have repaired a fistula - a potentially fatal tissue abnormality - in the man's lower airway. "This is another interesting new therapeutic approach for stem cells," said lead researcher Dr. Francesco Petrella, deputy director of thoracic surgery at the European Institute of Oncology in Milan, Italy.

http://ift.tt/1y8i8Li

Stem cell therapy may slow down the progression of Huntington's Disease

Huntington's is a deadly, inherited disease that strikes patients during their prime years of life. It affects about thirty-thousand Americans, and there are 150-thousand more who are at risk.

http://ift.tt/1y8uRh6

A pill for dementia moves closer thanks to stem cell research

Using stem cells from patients with an inherited form similar to Alzheimer's, called frontotemporal dementia, the team in Belgium recreated the disease in a lab dish to help them find how to treat it. They discovered a gene mutation that stops normal cells forming, and were able to correct it with a compound that blocked a chemical responsible for the fault.

http://ift.tt/13TXlxK

Report on remission in patients with MS three years after stem cell transplant

Three years after a small number of patients with multiple sclerosis were treated with high-dose immunosuppressive therapy and then transplanted with their own hematopoietic stem cells, most of the patients sustained remission of active relapsing-remitting MS and had improvements in neurological function, according to a study. Three years after a small number of patients with multiple sclerosis were treated with high-dose immunosuppressive therapy and then transplanted with their own hematopoietic stem cells, most of the patients sustained remission of active relapsing-remitting MS and had improvements in neurological function, according to a study published online by JAMA Neurology .

http://ift.tt/1AcMuKI

Pi3kcb Links Hippo-YAP and PI3K-AKT Signaling Pathways to Promote...

From the Department of Cardiology, Boston Children's Hospital, MA ; Department of Pediatric Cardiology and Intensive Care, MHH-Hannover Medical School, Hannover, Germany ; Department of Anatomy, School of Basic Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China ; Department of Cardiology, Leiden University Medical Center, The Netherlands ; and Harvard Stem Cell Institute, Harvard University, Cambridge, MA . Correspondence to Dr William T. Pu, Department of Cardiology, Children's Hospital Boston, Enders 1254, 300 Longwood Ave, Boston, MA 02115.

http://ift.tt/1vH2II1

Similar Effect of Autologous and Allogeneic Cell Therapy for Ischemic ...

From the Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands ; and Center for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom . Correspondence to Steven A.J. Chamuleau, MD, PhD, Department of Cardiology, University Medical Center Utrecht, Heidelberglaan 100, Room E03-808, Utrecht 3584CX, The Netherlands.

http://ift.tt/1xhoWEA

Allogeneic Cell Therapy: A New Paradigm in Therapeutics [Editorials]

Correspondence to Joshua M. Hare, MD, Interdisciplinary Stem Cell Institute, Biomedical Research Bldg, 1501 NW 10th Ave, Room 824, PO Box 016960 , Miami, FL 33136. E-mail Cell-based therapy is at the forefront of clinical investigation for cardiovascular disease, backed by over a decade of rigorous preclinical study of cell biology, mechanism of action, immunology, and phenotypic efficacy.

http://ift.tt/1xhoWod

Questions linger over stress-induced stem cells

The latest investigation into a debunked method of generating stem cells has left researchers grappling with questions about what went wrong in a laboratory at the RIKEN research institute in Japan. The final report from the independent investigation, released on 26 December, bolstered suspicions that the stem cells - which were supposedly generated by applying stress to ordinary adult cells in an acid bath - were actually embryonic stem cells that had been introduced to the samples.

http://ift.tt/1I0x3Ht

Stem cell transplants may halt progression of multiple sclerosis

Three-year outcomes from an ongoing clinical trial suggest that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells may induce sustained remission in some people with relapsing-remitting multiple sclerosis . RRMS is the most common form of MS, a progressive autoimmune disease in which the immune system attacks the brain and spinal cord.

http://ift.tt/1tm2TYo

A Young Man of Principle

... This movement should be leading the charge in offering Halachic analysis on the issues of embryonic stem cell research, cloning, homosexual relationships, and other facets of our society left unaddressed by our tradition rather than regressing from ...

http://ift.tt/1rAR98I

Interim Results Reported from Clinical Trial of Stem Cell...

A nationwide team of researchers report on interim results from a small, five-year study of transplantation of the individuals' own hematopoietic stem cells combined with high-dose immunotherapy in 24 people with relapsing-remitting MS. This procedure aims at "rebooting" the immune system to prevent MS immune attacks against the brain and spinal cord.

http://ift.tt/1xzFI0Q

Dementia reversed with new stem cell procedure

The late actor committed suicide in August, following his diagnosis of Parkinson's disease. But the latest report suggests it might have been Lewy body dementia that ultimately lead to his death.

http://ift.tt/1vtSpGb

One Reason Neuralstem (CUR) Stock is Rising Today

The company describes NurOwn as an "autologous, adult stem cell therapy technology" designed to treat ALS, also known as Lou Gehrig's Disease. STOCKS TO BUY: TheStreet Quant Ratings has identified a handful of stocks that can potentially TRIPLE in the next 12 months.

http://ift.tt/1xgD54X

Fresh hope for dementia patients

Cells used to study "dementia in a dish" have led scientists to a potential new treatment strategy for an inherited form of the brain disease. Defective stem cells grown in the lab revealed a signalling pathway linked to frontotemporal dementia , which accounts for about half of dementia cases before the age of 60. Treatment with a drug that suppressed the pathway, known as "Wnt", restored the ability of neurons affected by the disease to develop normally.

http://ift.tt/13KbdKz

Patient stem cells used to make dementia-in-a-dish; help identify new treatment strategy

Induced pluripotent stem cells derived from patients with frontotemporal dementia were genetically corrected and converted to cortical neurons. The green staining indicates the cortical marker CTIP2, the red stain is the neuronal marker TUJ1, and the blue stains the nuclei of the cells.

http://ift.tt/1x4B2kJ

6 Science Stories For 2014

'Tis the season for listicles rounding up the stories of the year. So with, the authority vested in me, here is a selection of six top, bottom and forgotten science stories of 2014.

http://ift.tt/1AbbXEy

Brainstorm Cell Therapeutics (BCLI) Stock Rises Ahead of ALS Treatment Trial Data Release

Brainstorm intends to release the final results from its Phase 2a trial of its stem cell therapy NurOwn on Monday. The company describes NurOwn as an "autologous, adult stem cell therapy technology" designed to treat ALS, also known as Lou Gehrig's Disease.

http://ift.tt/1AbbXEs

High-fat diet, obesity during pregnancy harms stem cells in developing fetus

Physician-scientists at OHSU Doernbecher Children's Hospital reveal a high-fat diet and obesity during pregnancy compromise the blood-forming, or hematopoietic, stem cell system in the fetal liver responsible for creating and sustaining lifelong blood and immune system function. The life-long burden of a western-style diet on the heart and circulatory system have long been appreciated.

http://www.medicalnewstoday.com/releases/287468.php

Inspirational women lead the way for Herts in Queen's New Year Honours

A woman with a passion for sport and another who championed children's mental health services who sadly passed away yesterday feature in the New Year's Honours List. Betty Longhurst of Tring has been chairman of the Tring Squash and Rackets Club for 12 years, and despite a back injury currently ruling her out of the court, usually plays three times a week.

http://www.tringtoday.co.uk/news/more-news/inspirational-women-lead-the-way-for-herts-in-queen-s-new-year-honours-1-6496801

Study shows that reprogramming stem cells can prevent cancer following full body radiation

The body has evolved ways to get rid of faulty stem cells. A University of Colorado Cancer Center study published today in the journal Stem Cells shows that one of these ways is a "program" that makes stem cells damaged by radiation differentiate into other cells that can no longer survive forever.

http://www.news-medical.net/news/20141231/Study-shows-that-reprogramming-stem-cells-can-prevent-cancer-following-full-body-radiation.aspx

LIBD announces significant advances in identifying causes of schizophrenia, brain disorders

The Lieber Institute for Brain Development announces significant advances in identifying the causes of schizophrenia and related developmental brain disorders and translating these findings into new treatment strategies. CRACKING THE CODE OF BRAIN DEVELOPMENT: Two papers published by the LIBD research team report progress identifying specific biological signatures that guide early brain development and can ultimately lead to neurodevelopmental disorders such as autism spectrum disorder and schizophrenia.

http://www.news-medical.net/news/20141231/LIBD-announces-significant-advances-in-identifying-causes-of-schizophrenia-brain-disorders.aspx

Sacramento teen with sickle cell anemia hopes for a medical match

A Sacramento teenager living with sickle cell anemia hopes to start 2015 with a medical match. A bone marrow or stem cell transplant is the only cure for her disease, but with the donor pool so small, it will take a lot more people stepping to the plate before her chances of finding a genetic match improve.

http://www.kcra.com/news/sacramento-teen-with-sickle-cell-anemia-hopes-for-a-medical-match/30469556?absolute=true

Stemgent, Inc. - Medical Equipment - Deals and Alliances Profile - New Market Study Published

It focuses on the development of innovative technology and application solutions for the advancement of stem cell research. The company's product portfolio comprises antibodies, cell lines, cytokines / proteins, differentiation, matrices, media, reprogramming systems, small molecules and transfection.

http://reports.pr-inside.com/stemgent-inc-medical-equipment-r4181934.htm

A New Year's Resolution for You

New Year's Resolutions tend towards the personal: lose weight, take up a hobby, spend more time with the family, get up earlier, read great books, etc. But this new year I beg people to take some time to learn more about bioethics.

http://townhall.com/columnists/zacharygappa/2014/12/31/a-new-years-resolution-for-you-n1937236

Hogan says city should drive state economy

... Inner Harbor, the port of Baltimore and Harbor East, along with state tax credits for biotechnology and stem cell research. "It's not like you're going to attract business unless there's some kind of incentive for them to go in there and make ...

http://www.baltimoresun.com/news/maryland/baltimore-city/bs-md-hogan-baltimore-economy-20141230-story.html

Tuesday, December 30, 2014

Just Published: "Memorial Sloan Kettering Cancer Center -...

The center provides cancer treatment, cancer research and cancer education programs. It conducts research in the therapeutic areas of bone and marrow stem cell transplantation, cancer pathology, cancer therapeutics and drug development, cell biology, cell cycle regulation, cell death, cell signaling, immunology, genetics and genomics, molecular imaging, and tumor growth, among others.

http://reports.pr-inside.com/just-published-memorial-sloan-kettering-r4181671.htm

Reprogramming Stem Cells May Prevent Cancer After Radiation

The body has evolved ways to get rid of faulty stem cells. A University of Colorado Cancer Center study published in the journal Stem Cells shows that one of these ways is a "program" that makes stem cells damaged by radiation differentiate into other cells that can no longer survive forever.

http://www.biosciencetechnology.com/news/2014/12/reprogramming-stem-cells-may-prevent-cancer-after-radiation

Afghan child undergoes bone marrow transplant in Bengaluru

A four-year-old Afghan child successfully underwent a bone marrow transplant for a rare bone marrow disease, called Amegakaryocytic Thrombocytopenia, at a city hospital here. Kulraj, son of an Afghan Sikh refugee was diagnosed with the disease at the age of two.

http://www.newkerala.com/news/2014/fullnews-144705.html

Japanese researcher fails to replicate her 'stem cell breakthrough'

... in Osaka, Japan, on April 9, during the height of the scandal arising from her supposedly "game-changing" stem cell research. Still, to give Obokata benefit of the doubt, Riken decided to replicate the results of her research. But, as it turns out, ...

http://www.thestar.com.my/Lifestyle/Features/2014/12/31/Japanese-researcher-fails-to-replicate-her-stem-cell-breakthrough/

http://www.dreamstime.com/royalty-free-stock-photo-concept-scientific-research-image23899445

Physical disability and other signs of disease progression came to a dead stop among individuals affected by relapsing-remitting multiple sclerosis and showed no sign of return 3 years after being treated with immunosuppressive therapy and stem cell transplant. The treatment was part of a study funded by the National Institute of Allergy and Infections Diseases , and conducted by the NIAID-funded Immune tolerance Network .

http://www.rehabpub.com/2014/12/ms-symptoms-halt-3-years-stem-cell-transplant/

Stem Cell Treatment For MS Patients Improves Their Immune System And Extends Remission

A new stem cell treatment might be an effective therapy for people suffering from multiple sclerosis (MS), a disease in which the immune system attacks and damages myelin.

http://www.medicaldaily.com/stem-cell-treatment-ms-patients-improves-their-immune-system-and-extends-remission-315874

Now Available: BrainStorm Cell Therapeutics Inc. (BCLI) -...

The company develops autologous stem cell therapies for debilitating neurodegenerative diseases, such as amyotrophic lateral sclerosis, multiple sclerosis and Parkinson's disease. It develops NurOwn technology for the propagation and differentiation of autologous mesenchymal stem cells into neurotrophic factor -secreting cells and their transplantation at or near the site of damage.

http://reports.pr-inside.com/now-available-brainstorm-cell-therapeutics-inc-r4181323.htm

Malones donate $42.5 million to CSU for new stem-cell research facility

The largest ever cash donation to Colorado State University stems from a novel treatment to get a dressage horse with a bum knee back into the show ring.

http://www.reporterherald.com/business/ci_27224411/malones-donate-42-5-million-csu-new-stem

Reprogrammed stem cells may stop cancer post radiation

A University of Colorado Cancer Center study showed that one of the ways to get rid of such stem cells is a "program" that makes stem cells damaged by radiation differentiate into other cells that can no longer survive forever. The study also showed that this same safeguard of "programmed mediocrity" that weeds out stem cells damaged by radiation allows blood cancers to grow in cases when the full body is irradiated.

http://www.newkerala.com/news/2014/fullnews-144810.html

Stem Cell Transplants May Halt Progression of Multiple Sclerosis

Three-year outcomes from an ongoing clinical trial suggest that high-dose immunosuppressive therapy followed by the transplantation of a person's own blood-forming stem cells may induce sustained remission in some people with relapsing-remitting multiple sclerosis . RRMS is the most common form of MS, a progressive autoimmune disease in which the immune system attacks the brain and spinal cord.

http://www.pharmscope.com/news/2014-12-30-000000/stem-cell-transplants-may-halt-progression-multiple-sclerosis

Natural killer cells in the treatment of high-risk acute leukaemia.

Several studies have shown that in patients with acute leukaemia given allogeneic haematopoietic stem cell transplantation large part of the therapeutic effect lies on the anti-tumour effect displayed by cells of both adaptive and innate immunity. This evidence has also opened new scenarios for the treatment of patients with other haematological malignancies/solid tumours.

http://www.citeulike.org/user/jrifon/article/13471464

Soluble urokinase receptor is a biomarker of cardiovascular disease in chronic kidney disease

Correspondence: Björn Meijers, UZ Leuven, Department of Nephrology, Herestraat 49, Leuven 3000, Belgium. E-mail: bjorn.meijers@uz.kuleuven.ac.be Soluble urokinase-type plasminogen activator receptor accumulates in patients with chronic kidney disease .

http://www.nature.com/ki/journal/v87/n1/full/ki2014197a.html

A modulator of social behavior identified in frontotemporal dementia

When we think of dementia, we normally jump straight to Alzheimer's disease; the constant forgetting, the failure to recognize loved ones, changes in mood, etc. Alzheimer's disease is a large health concern and was even featured in this year's Google Zeitgeist.

http://scienceblog.com/76028/modulator-social-behavior-identified-frontotemporal-dementia/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+scienceblogrssfeed+%28ScienceBlog.com%29

MS Remission Sustained Three Years Post-Stem Cell Transplant

For patients with relapsing-remitting multiple sclerosis , high-dose immunosuppressive therapy with autologous hematopoietic cell transplant is associated with sustained remission and improvements in neurologic function, according to research published online Dec. 29 in JAMA Neurology . Richard A. Nash, M.D., from the Colorado Blood Cancer Institute in Denver, and colleagues examined the safety, efficacy, and durability of MS disease stabilization for patients with RRMS who were evaluated through five years after HCT.

http://www.mentalhelp.net/poc/view_doc.php?type=news&id=169582&cn=75

Stopping Multiple Sclerosis with Stem Cell Transplants

Relapsing-remitting multiple sclerosis is the most common form of MS, a progressive autoimmune disease in which the immune system attacks the brain and spinal cord. Washington, DC - infoZine - Three-year outcomes from an ongoing clinical trial suggest that high-dose immunosuppressive therapy followed by transplantation of a person's own blood-forming stem cells may induce sustained remission in some people with relapsing-remitting multiple sclerosis .

http://www.infozine.com/news/stories/op/storiesView/sid/60697/

Baldness Breakthrough: Novel Way To Spur Hair Growth Discovered, Reveals

CNIO Researchers Activate Hair Growth By Modifying Immune Cells How to restore hair loss is a task not undertaken exclusively by beauty practitioners. The discovery, now published by a group from the Spanish National Cancer Research Centre , reveals a novel angle to spur hair follicle growth.

http://www.biospace.com/news_story.aspx?StoryID=359386&full=1

Following Up on a Trial of an Immune System Reset to Treat Multiple Sclerosis

Do you want to live a longer life in good health? Simple practices can make some difference, such as exercise or calorie restriction. But over the long haul all that really matters is medical biotechnology: progress towards repair and reversal of the known root causes of aging.

https://www.fightaging.org/archives/2014/12/following-up-on-a-trial-of-an-immune-system-reset-to-treat-multiple-sclerosis.php

High-fat diet, obesity during pregnancy harms stem cells in developing fetus

Physician-scientists reveal a high-fat diet and obesity during pregnancy compromise the blood-forming, or hematopoietic, stem cell system in the fetal liver responsible for creating and sustaining lifelong blood and immune system function. Physician-scientists at OHSU Doernbecher Children's Hospital reveal a high-fat diet and obesity during pregnancy compromise the blood-forming, or hematopoietic, stem cell system in the fetal liver responsible for creating and sustaining lifelong blood and immune system function.

http://www.sciencedaily.com/releases/2014/12/141224103111.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fmost_popular+%28Most+Popular+News+--+ScienceDaily%29

CSU Receives $42.5 Million Gift for Regenerative Medicine

The largesse was inspired in part by stem cell treatments the Malones' world-class dressage horses have received to help repair stressed and injured joints. Philanthropists John Malone, MS, PhD, and his wife Leslie Malone, fascinated by the healing power of stem cells, have committed a record $42.5 million to Colorado State University to develop regenerative medical therapies for animals and people.

http://www.thehorse.com/articles/35105/csu-receives-42-5-million-gift-for-regenerative-medicine?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%253a%2BTheHorse%252fNews%2B(TheHorse.com%2B-%2BNews)

Reprogrammed stem cells may stop cancer post radiation :Study

A new study has shown that reprogramming stem cells could help prevent cancer post radiation. A University of Colorado Cancer Centre study showed that one of the ways to get rid of such stem cells is a "program" that makes stem cells damaged by radiation differentiate into other cells that can no longer survive forever.

http://www.dnaindia.com/health/report-reprogrammed-stem-cells-may-stop-cancer-post-radiation-study-2048101

Leyland woman's hope for future after beating cancer

Congratulations, you're now registered! Let us know what news and updates you want to hear about and we'll send them straight to your inbox. A young woman who spent more than a decade undergoing cancer treatment is celebrating after being told she is in remission.

http://www.leylandguardian.co.uk/news/local/leyland-woman-s-hope-for-future-after-beating-cancer-1-7025391

Blue Skies - the future of regenerative medicine, with Stephen Minger

Dr. Stephen Minger is one of the world's leading experts on stem cells. In this talk, he will review the state of play with stem cell research, regenerative medicine, and cell-based therapies, before covering some "Blue Skies" technologies that will revolutionise the future of medicine even further.

http://www.kurzweilai.net/blue-skies-the-future-of-regenerative-medicine-with-stephen-minger

Andrew donates bone marrow after hearing about brave boy

Andrew, 29, from Southend, signed up to the bone marrow transplant register after hearing about 21-month-old Jack Kleinberg. Jack, of St James Gardens, Westcliff , is facing the second bone marrow transplant in his short life to help him beat two life-threatening conditions.

http://www.echo-news.co.uk/news/11692190.Andrew_donates_bone_marrow_after_hearing_about_brave_boy/

Andrew donates bone marrow after hearing about brave boy

Andrew, 29, from Southend, signed up to the bone marrow transplant register after hearing about 21-month-old Jack Kleinberg. Jack, of St James Gardens, Westcliff , is facing the second bone marrow transplant in his short life to help him beat two life-threatening conditions.

http://www.southendstandard.co.uk/news/11692190.Andrew_donates_bone_marrow_after_hearing_about_brave_boy/

Reprogramming stem cells may prevent cancer after radiation

Pre-programmed stem cell death allows cancer to grow after full-body irradiation, researchers report, and NOTCH signaling may restore stem cell function, protecting against cancer after radiation. The body has evolved ways to get rid of faulty stem cells.

http://www.sciencedaily.com/releases/2014/12/141229141414.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fstem_cells+%28Stem+Cells+News+--+ScienceDaily%29

How economic insecurity impacts diabetes control among patients

Difficulty paying for food and medications appears to be associated with poor diabetes control among patients in a study that examined the impact of economic insecurity on managing the disease and the use of health care resources, according to a report. Difficulty paying for food and medications appears to be associated with poor diabetes control among patients in a study that examined the impact of economic insecurity on managing the disease and the use of health care resources, according to a report published online by JAMA Internal Medicine .

http://www.sciencedaily.com/releases/2014/12/141229164852.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fdiabetes+%28Diabetes+News+--+ScienceDaily%29

Estrogen worsens allergic reactions in mice

Estradiol, a type of estrogen, enhances the levels and activity in mice of an enzyme that drives life-threatening allergic reactions, according to researchers. The study results may help explain why women frequently experience more severe allergic reactions compared to men.

http://www.sciencedaily.com/releases/2014/12/141229092558.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fallergy+%28Allergy+News+--+ScienceDaily%29

Protein identified as possible universal therapeutic target for many infections, including Ebola

A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, Influenza, Hepatitis and superbug bacteria such as Methicillin-resistant Staphylococcus epidermidis and Methicillin-resistant Staphylococcus aureus, according to a study. A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, Influenza, Hepatitis and superbug bacteria such as MRSE and MRSA, according to a Virginia Commonwealth University-led pre-clinical study published this month in the Journal of Cellular Physiology .

http://www.sciencedaily.com/releases/2014/12/141229122202.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fgenes+%28Genes+News+--+ScienceDaily%29

Locking mechanism found for 'scissors' that cut DNA

The mechanism that keeps an enzyme from becoming overzealous in its clipping of DNA has been discovered by researchers. Since controlled clipping is required for the production of specialized immune system proteins, an understanding of what keeps the enzyme in check should help explain why its mutant forms can lead to immunodeficiency and cancer.

http://www.sciencedaily.com/releases/2014/12/141225143548.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fgenes+%28Genes+News+--+ScienceDaily%29

Tomorrow's Healing Today

... In the U.S. the pharmaceutical-industrial-complex isn't rushing to invest in biological medicine or stem cell research on the scale that's needed. Their business model is focused more on the manufacturing of drugs with lucrative patents. Biological ...

http://www.psychologytoday.com/blog/beyond-good-and-evil/201412/tomorrows-healing-today

Monday, December 29, 2014

Comparing analgesic effect of manual vs laser acupuncture for lateral epicondylalgia

Comparing the analgesic effect of laser acupuncture and manual acupuncture for treating lateral epicondylalgia, applying manual acupuncture on lateral epicondylalgia produced stronger evidence of analgesic effect than laser acupuncture did in meta-analysis. A team of researchers from China Medical University and Da-Chien General Hospital in Taiwan recently compared the analgesic effect of laser acupuncture and manual acupuncture for the treatment of lateral epicondylalgia.

http://www.sciencedaily.com/releases/2014/12/141229092604.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fneuropathy+%28Neuropathy+News+--+ScienceDaily%29

Ebola, comet landing and 2014's other top science news

In November 2014, humans landed a probe on a comet - for the first time. Despite a tiny issue with harpoons, the European Space Agency probe, Philae, survived the landing and went on to sniff out some organic molecules on Comet 67P/Churyumov-Gerasimenko before going into sleep mode.

http://www.oregonlive.com/multimedia/index.ssf/2014/12/ebola_comet_landing_and_2014s.html

Report on remission in patients with MS three years after stem cell transplant

Mechanism of toxin's inflammatory effect on lungs found

A never-before-seen mechanism by which a bacterial toxin leads to severe inflammation in asthma and other acute and chronic pulmonary diseases has been discovered by researchers. The discovery could result in development of therapeutic strategies that improve health in individuals who suffer from airway diseases, experts say.

http://www.sciencedaily.com/releases/2014/12/141229141424.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily+%28Latest+Science+News+--+ScienceDaily%29

Reprogrammed Cells and Radiation

It's no big secret that being exposed to radiation can cause cancer. As humans, we rely on radioactigve materials and manufacture technologies to harness that power for our benefit, but that doesn't keep accidents from happening.

http://community.advanceweb.com/blogs/al_2/archive/2014/12/29/reprogrammed-cells-and-radiation.aspx

Malones donate $42.5 million to CSU for new stem-cell research facili

The largest ever cash donation to Colorado State University stems from a novel treatment to get a dressage horse with a bum knee back into the show ring. John and Leslie Malone's $42.5 million gift, announced Monday, will create the CSU Institute for Biologic Translational Therapies in the College of Veterinary Medicine and Biomedical Sciences, a 100,000-square-foot facility to develop stem-cell research into commercially viable treatments for animals and humans.

http://www.denverpost.com/business/ci_27224411/malones-donate-42-5-million-csu-new-stem?source=rss

Stem Cell Therapy for MS Shows Promise

An experimental therapy that kills off and then "resets" the immune system has given three years of remission to a small group of multiple sclerosis patients, researchers say. About eight in 10 patients given this treatment had no new adverse events after three years.

http://www.webmd.com/multiple-sclerosis/news/20141229/stem-cell-therapy-for-ms-shows-promise?src=RSS_PUBLIC

Obesity, high-fat diets during pregnancy could...

Pregnant women who are obese or eating a diet high in fatty foods could unwittingly be harming their unborn child, according to new research published by the journal Molecular Metabolism . In the study, researchers from the Oregon Health and Science University Doernbecher Children's Hospital found that a high-fat diet and obesity during pregnancy could damage the hematopoietic stem cells of the fetal liver that are responsible for creating and sustaining blood and immune system function throughout a person's lifetime.

http://www.redorbit.com/news/health/1113305661/obesity-high-fat-diets-during-pregnancy-could-harm-fetus-122914/

Philanthropists And Propel Regenerative Medicine With Record $42.5 Million Gift To {1}

Philanthropists John and Leslie Malone, fascinated by the healing power of stem cells, have committed a record $42.5 million to Colorado State University to develop regenerative medical therapies for animals and people. It is the largest cash gift in university history, a remarkable commitment to improved human and animal health and well-being.

http://www.biospace.com/news_story.aspx?StoryID=359366&full=1

John Malone, wife donate $42.5M to Colorado State

Media magnate John Malone and his wife, Leslie, are giving $42.5 million to Colorado State University to develop stem cell and other treatments for animals and people, the biggest donation in the school's history, the university announced Monday. The gift will be used to create the CSU Institute for Biologic Translational Therapies, with $32.5 million paying for half of the construction of its building and $10 million covering operational costs.

http://www.washingtontimes.com/news/2014/dec/29/malones-donating-425m-to-colorado-state/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+Sports-TheWashingtonTimesAmericasNewspaper+%28Sports+-+The+Washington+Times%29

Stem Cell Therapy for MS Shows Promise

An experimental therapy that kills off and then "resets" the immune system has given three years of remission to a small group of multiple sclerosis patients, researchers say. About eight in 10 patients given this treatment had no new adverse events after three years.

http://news.health.com/2014/12/29/stem-cell-therapy-for-ms-shows-promise/

Study sheds light on what causes cells to divide

When a rapidly-growing cell divides into two smaller cells, what triggers the split? Is it the size the growing cell eventually reaches? Or is the real trigger the time period over which the cell keeps growing ever larger? A novel study has finally provided an answer to this long unsolved conundrum. And it's not what many biologists expected.

http://www.sciencedaily.com/releases/2014/12/141225143552.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Ftop_news+%28ScienceDaily%3A+Top+News%29

Mechanical stress acts via katanin to amplify differences in growth...

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. The presence of diffuse morphogen gradients in tissues supports a view in which growth is locally homogenous.

http://www.citeulike.org/user/emmasaragossi/article/13471131

Stem Cell Therapy for MS Shows Promise

An experimental therapy that kills off and then "resets" the immune system has given three years of remission to a small group of multiple sclerosis patients, researchers say. About eight in 10 patients given this treatment had no new adverse events after three years.

http://health.usnews.com/health-news/articles/2014/12/29/stem-cell-therapy-for-ms-shows-promise

Stem cell transplant may help patients with MS

An experimental treatment that uses a patient's own stem cells may offer new hope for people with multiple sclerosis. In a small clinical trial, patients experienced long-term disease remission after undergoing a transplant of their own hematopoietic stem cells.

http://www.cbsnews.com/news/stem-cell-transplant-may-help-manage-ms/

Report on remission in patients with multiple sclerosis three years after stem cell transplant

Demyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion.

http://medicalxpress.com/news/2014-12-remission-patients-multiple-sclerosis-years.html

Stem cell transplants may halt progression of multiple sclerosis

Global, Collaborative Approach Advances Quest for Better Treatments of Mental Illness

BALTIMORE, Dec. 29, 2014 /PRNewswire-USNewswire/ -- The Lieber Institute for Brain Development announces significant advances in identifying the causes of schizophrenia and related developmental brain disorders and translating these findings into new treatment strategies: CRACKING THE CODE OF BRAIN DEVELOPMENT: Two papers published by the LIBD research team report progress identifying specific biological signatures that guide early brain development and can ultimately lead to neurodevelopmental disorders such as autism spectrum disorder and schizophrenia. The teams investigated whether prenatal expression of psychiatric disease-associated genes may be responsible for 'kick starting' atypical brain development.

http://www.freshnews.com/news/1028774/global-collaborative-approach-advances-quest-better-treatments-mental-illness

Record $US42.5 million gift to university for regenerative medicine

Dr Wayne McIlwraith, center, chats with John and Leslie Malone, who are giving a record $US42.5 million to Colorado State University to develop regenerative medicine. Philanthropists John and Leslie Malone have given a record $US42.5 million gift to Colorado State University to develop regenerative medicine, having been inspired in part by the stem-cell treatments their dressage horses received to help repair stressed and injured joints.

http://horsetalk.co.nz/2014/12/30/record-42m-gift-university-regenerative-medicine/

Enzyme's alter ego helps activate the immune system

Already known to cut proteins, the enzyme SPPL3 turns out to have additional talents, according to a new study. In its newly discovered role, SPPL3 works without cutting proteins to activate T-cells, the immune system's foot soldiers.

http://www.sciencedaily.com/releases/2014/12/141229092602.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fimmune_system+%28Immune+System+News+--+ScienceDaily%29

Malones give $42.5 million to CSU; biggest gift in school's history

Media magnate John Malone and his wife, Leslie, have given Colorado State University the largest single gift in the school's history - a $42.5 million commitment for the study of regenerative medicine in animals and people. The donation will launch what's being called the CSU Institute for Biologic Translational Therapies, which will focus on developing regenerative treatments "from inception in the laboratory setting, through clinical trials, to commercialization of new technologies."

http://www.bizjournals.com/denver/news/2014/12/29/malones-give-42-5-million-to-csu-biggest-gift-in.html?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+vertical_43+%28Networking+Industry+News%29

Reprogramming Stem Cells May Prevent Cancer After Radiation

The body has developed a way to neutralize stem cells damaged by radiation, and fine-tuning this process may help prevent cancer in the aftermath of full-body radiation, a study suggests. The University of Colorado Cancer Center study, published in the journal Stem Cells, describes a natural "program" that makes stem cells damaged by radiation differentiate into other cells that can no longer survive forever.

http://www.formkit.com/news/2014-12-29-000000/reprogramming-stem-cells-may-prevent-cancer-after-radiation

Protein May Be a Universal Therapeutic Target for Many Infections

A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, influenza, hepatitis, and superbug bacteria such as methicillin-resistant Staphylococcus aureus , according to a pre-clinical study published this month in the Journal of Cellular Physiology . By using a drug combination of the clinically tested OSU-03012 and FDA-approved phosphodiesterase 5 inhibitors to target GRP78 and related proteins, researchers prevented the replication of a variety of major viruses in infected cells, made antibiotic-resistant bacteria vulnerable to common antibiotics, and found evidence that brain cancer stem cells were killed.

http://www.pharmscope.com/news/2014-12-29-000000/protein-may-be-universal-therapeutic-target-many-infections

Malones give record $42.5 million to CSU

Cable TV magnate John Malone and his wife, Leslie, have committed a record $42.5 million to Colorado State University to develop regenerative stem cell therapies for animals and people. The donation, the largest cash gift in the university's history, will launch the CSU Institute for Biologic Translational Therapies to investigate remedies, including ones derived from stem cells, to treat disease and other ailments.

http://bizwest.com/malones-give-record-42-5-million-to-csu/

Reprogramming stem cells may prevent cancer after radiation

... ... Led by Dr. Hanna Mikkola, a member of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, UCLA scientists have discovered a protein that is integral to the self-replication of hematopoietic stem ... Scientists at the ...

http://medicalxpress.com/news/2014-12-reprogramming-stem-cells-cancer.html

Reprogramming Stem Cells May Prevent Cancer After Radiation

The body has evolved ways to get rid of faulty stem cells. A University of Colorado Cancer Center study published today in the journal Stem Cells shows that one of these ways is a "program" that makes stem cells damaged by radiation differentiate into other cells that can no longer survive forever.

http://www.newswise.com/articles/view/627864/?sc=rsla&utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+NewswiseLatestNews+%28Newswise%3A+Latest+News%29

A clinician's guide to double hit lymphomas

Double hit lymphomas represent a subset of highly aggressive B-cell malignancies characterized by the presence of recurrent cytogenetic rearrangements affecting MYC and either BCL2 and/or BCL6. Recent studies have expanded the concept to include MYC/BCL2 protein co-expressing lymphomas.

http://www.citeulike.org/user/peterpath/article/13471051

Protein GRP78 identified as possible universal therapeutic target for ...

A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, Influenza, Hepatitis and superbug bacteria such as MRSE and MRSA, according to a Virginia Commonwealth University-led pre-clinical study published this month in the Journal of Cellular Physiology . By using a drug combination of the clinically tested OSU-03012 and FDA approved Phosphodiesterase 5 Inhibitors to target GRP78 and related proteins, researchers prevented the replication of a variety of major viruses in infected cells, made antibiotic-resistant bacteria vulnerable to common antibiotics and found evidence that brain cancer stem cells were killed.

http://medicalxpress.com/news/2014-12-protein-grp78-universal-therapeutic-multiple.html

Reprogramming stem cells may prevent cancer after radiation

The body has evolved ways to get rid of faulty stem cells. A University of Colorado Cancer Center study published today in the journal Stem Cells shows that one of these ways is a "program" that makes stem cells damaged by radiation differentiate into other cells that can no longer survive forever.

http://www.eurekalert.org/pub_releases/2014-12/uocd-rsc122914.php

More about Gordie Howe's therapy

Dr. David Gorski, a prominent skeptic of therapies offered outside the scientifically controlled clinical trial system, has published an extensive and critical look at the stem cell therapy Gordie Howe received in early December to help him recover from a serious stroke. I had email exchanges with Gorski while writing my article last week on the treatment, using stem cells provided by San Diego-based Stemedica.

http://www.utsandiego.com/news/2014/dec/29/gordie-howe-gorski-stem-cells/

BioTime Appoints Adi Mohanty Chief Operating Officer

BioTime, Inc. , a leader in developing pluripotent stem-cell therapies and other technologies designed to address major unmet medical needs, today announced the appointment of Adi Mohanty to the position of Chief Operating Officer of the Company. Mr. Mohanty's primary responsibilities will be to build BioTime's business through the development of its subsidiaries and through the further development and commercialization of BioTime's HyStem "The addition of Adi to our senior management team is another execution milestone for BioTime as we broaden our capabilities to address market opportunities and build shareholder value," said Dr. West.

http://www.freshnews.com/news/1028660/biotime-appoints-adi-mohanty-chief-operating-officer

High-fat diet, obesity during pregnancy can hurt stem cells in fetus, OHSU finds

A new study by Oregon Health & Science University suggests that eating a high-fat diet and being obese during pregnancy could harm the fetal liver. Eating a high-fat diet and being obese are bad for the health regardless of the situation but they can also pose a threat during pregnancy, potentially harming the development of the fetus.

http://www.oregonlive.com/health/index.ssf/2014/12/high-fat_diet_obesity_during_p.html

BioTime Appoints Adi Mohanty Chief Operating Officer

Mr. Mohanty's primary responsibilities will be to build BioTime's business through the development of its subsidiaries and through the further development and commercialization of BioTime's HyStem A -based products. Mr. Mohanty will report to Michael D. West, Ph.D., BioTime's Chief Executive Officer.

http://www.businesswire.com/news/home/20141229005141/en/BioTime-Appoints-Adi-Mohanty-Chief-Operating-Officer

Scientists zero in on how lung cancer spreads

Scientists have taken microscopic images revealing that the protein ties tethering cells together are severed in lung cancer cells -- meaning they can break loose and spread, according to research published in Cell Reports December 24. The researchers at the Cancer Research UK Manchester Institute discovered that the ties which lash cells together -- controlled by a protein called TIAM1 -- are chopped up when cell maintenance work goes wrong. Healthy cells routinely scrap old cell parts so they can be broken down and used again.

http://www.sciencedaily.com/releases/2014/12/141225143556.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fmost_popular+%28Most+Popular+News+--+ScienceDaily%29

Athersys Finishes Enrollment of Phase 2 Study of MultiStem(R) Cell Therapy for Ischemic Stroke

Athersys, Inc. today announced that it has concluded patient enrollment of its Phase 2 clinical study involving administration of Athersys' MultiStem cell therapy to ischemic stroke patients. The study is a randomized, double-blind, placebo-controlled, multi-center clinical trial evaluating the safety and efficacy of MultiStem therapy in subjects suffering moderate to moderate-severe ischemic strokes.

http://www.globenewswire.com/news-release/2014/12/29/694082/10113535/en/Athersys-Finishes-Enrollment-of-Phase-2-Study-of-MultiStem-R-Cell-Therapy-for-Ischemic-Stroke.html

Sunday, December 28, 2014

metformin

... alternative to daily insulin injections for type 2 patients , and a potential cure for type 1 after a stem cell research breakthrough . The stem cell research was inspired by a Harvard professor who wanted to find a cure for his son and daughter who ...

http://www.redorbit.com/news/health/1113305411/popular-type-2-diabetes-drug-safe-for-kidney-disease-patients-study-says-122814/

New Market Research Report: Acute Myeloid Leukemia Therapeutics Market to 2020

GBI Research, has released its latest pharma report, "Acute Myeloid Leukemia Therapeutics Market to 2020 - Treatment and prognosis in AML is strongly influenced by a patient's age, and their cytogenetic profile. In the majority of cases these two prognostic influences are linked, with a higher frequency of unfavorable cytogenetic abnormalities observed in the elderly.

http://reports.pr-inside.com/new-market-research-report-acute-myeloid-r4180699.htm

"BioTime, Inc. (BTX) - Medical Equipment - Deals and Alliances Profile" Published

It is focused on research and development in the field of regenerative medicine. The company's products can be used in various fields of medicine such as oncology, neuroscience, orthopedics and blood and vascular diseases.

http://reports.pr-inside.com/biotime-inc-btx-medical-equipment-r4180695.htm

Record competition for stem cell grants means tough choices for state officials

The competition for Maryland's stem cell research grants will be stiffer than ever as applications flood in next month, forcing officials to be more selective even as scientists worry that the state's fiscal problems and a new administration in Annapolis may mean smaller budgets in the future. The Maryland Stem Cell Research Commission received a record 240 letters declaring intent to apply for $10.4 million in grants, officials said this month.

http://www.baltimoresun.com/health/bs-hs-stem-cell-grants-20141226-story.html

Why I'm no longer a Conservative Jew

Cancer hope for Heather - 10 years on

Congratulations, you're now registered! Let us know what news and updates you want to hear about and we'll send them straight to your inbox. A Fylde coast businesswoman who spent more than a decade undergoing cancer treatment is celebrating after being told she is in remission.

http://www.lythamstannesexpress.co.uk/news/health/local-health/cancer-hope-for-heather-10-years-on-1-7022895

Saturday, December 27, 2014

Cancer Survivors Get Rose Parade Float Ride

Diana and Gavin Wolfrank explained how City of Hope supported them through their fight with Gavin's leukemia on Saturday, Dec. 27, 2014. When the Tournament of Roses Parade winds through Pasadena on Thursday, some people who've had thorny diseases will have a very rosy view.

http://www.nbclosangeles.com/news/local/City-of-Hopes-Float-Gives-Cancer-Survivors-Rose-Parade-Ride-of-a-Lifetime-286932711.html

Worse lower, higher, frequency hearing in HIV positive adults

Adults with the human immunodeficiency virus had poorer lower and higher frequency hearing than adults without HIV infection, according to a new report. Adults with the human immunodeficiency virus had poorer lower- and higher-frequency hearing than adults without HIV infection, according to a report published online by JAMA Otolaryngology-Head & Neck Surgery .

http://www.sciencedaily.com/releases/2014/12/141226211108.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fhearing_loss+%28Hearing+Loss+News+--+ScienceDaily%29

Now Available: Promega Corporation - Medical Equipment - Deals and Alliances Profile

... cell signaling, drug discovery, genetic identity, RNA analysis, protein purification and interactions, stem cell research, industrial and environmental monitoring, mixed sample detection, and stem cell functional analysis, among others. It operates ...

http://reports.pr-inside.com/now-available-promega-corporation-r4180321.htm

Canadian Blood Services seeking 1,000 blood donations in Sask.

Canadian Blood Services is urging the people of Saskatchewan to donate blood. It has about 1,000 open appointments for blood donations throughout the province over the next two weeks.

http://www.cbc.ca/news/canada/saskatoon/canadian-blood-services-seeking-1-000-blood-donations-in-sask-1.2884677?cmp=rss

Of mice and men: Differences found in cell development

Scientists say they have discovered a key factor in the lab formation of human primordial germ cells - the precursors to egg and sperm - and that it differs significantly from experiments involving rodent cells. In a paper published Wednesday in the journal Cell, researchers at the University of Cambridge in England and the Weizmann Institute of Science in Israel said their discovery raises questions about how much mouse experiments can tell us about early human cell development.

http://www.chinapost.com.tw/life/science-&-technology/2014/12/28/425053/Of-mice.htm

Science took a step back in 2014

In 2012, scientists finally cornered the elusive Higgs particle. In 2013, we learned the Voyager spacecraft had reached the space between stars.

http://www.usatoday.com/story/news/nation/2014/12/27/science-2014-blunders-end-year/20835069/?utm_source=feedblitz&utm_medium=FeedBlitzRss&utm_campaign=usatodaycomnation-topstories

Science took a step back in 2014

In 2012, scientists finally cornered the elusive Higgs particle, essential to explaining the most fundamental forces of nature. In 2013, we learned the Voyager spacecraft had reached the space between stars.

http://archive.coloradoan.com/usatoday/article/20835069?from=global

Diagnostic and risk criteria for HSCT-associated thrombotic...

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Transplant-associated thrombotic microangiopathy leads to generalized endothelial dysfunction that can progress to multiorgan injury, and severe cases are associated with poor outcomes after hematopoietic stem cell transplantation .

http://www.citeulike.org/user/eisei/article/13470485

Rudimentary egg and sperm cells made from stem cells

Some hope that sperm cells could one day be derived from the skin cells of a man who is otherwise sterile - and that a similar process cold produce viable egg cells from a sterile woman's body. Israeli and UK researchers have created human sperm and egg precursor cells in a dish, starting from a person's skin cells.

http://www.nature.com/news/rudimentary-egg-and-sperm-cells-made-from-stem-cells-1.16636

Record competition for stem cell grants means tough choices for state officials

... and is administered by Mainstream Media EC on behalf of Big News Network. The competition for Maryland's stem cell research grants will be stiffer than ever as applications flood in next month, forcing officials to be more selective even as ...

http://www.bignewsnetwork.com/index.php/sid/228889163

CLP slush fund ties revealed

... of Territory retailers, with bargain hunters flocking to Boxing Day sales. FROM space exploration to stem cell research and the origins of sex, it's been a golden year for scientists. Here are the top 10 science stories of 2014. STEVE Smith has ...

http://www.ntnews.com.au/news/northern-territory/developers-paid-up-to-55k-each-to-clp-fund-foundation-51/story-fnk0b1zt-1227167967616?from=nt+news_rss

Glenorchy house destroyed by fire

... fire in Glenorchy this morning and a shooting incident earlier this month. FROM space exploration to stem cell research and the origins of sex, it's been a golden year for scientists. Here are the top 10 science stories of 2014. UPDATED 2PM: ...

http://www.themercury.com.au/news/tasmania/glenorchy-house-destroyed-by-fire/story-fnj4f7k1-1227167718364?from=public_rss

Friday, December 26, 2014

Tassie yachts hold their own

... fire in Glenorchy this morning and a shooting incident earlier this month. FROM space exploration to stem cell research and the origins of sex, it's been a golden year for scientists. Here are the top 10 science stories of 2014. UPDATED 2PM: ...

http://www.themercury.com.au/sport/tassie-yachts-hold-their-own-as-race-passes-24-hour-mark/story-fnj4f7j4-1227167758458?from=public_rss

Perpetual Loyal retires, Comanche leads

... fire in Glenorchy this morning and a shooting incident earlier this month. FROM space exploration to stem cell research and the origins of sex, it's been a golden year for scientists. Here are the top 10 science stories of 2014. Luna Park Sydney ...

http://www.themercury.com.au/perpetual-loyal-retires-comanche-wild-oats-team-raggamuffin-leading-70th-sydney-to-hobart-yacht-race/story-fnj3twbb-1227167086895?from=public_rss

Glenorchy house damaged by fire

Japan lab dismisses stem cell study

Japan's top research institute on Friday hammered the final nail in the coffin of what was once billed as a ground-breaking stem cell study, dismissing it as flawed and saying the work could have been fabricated. The revelations come a week after a young researcher at the centre of the scandal, which has rocked the country's scientific establishment, said she would resign after failing to reproduce the successful conversion of an adult cell into a stem cell-like state, known as 'STAP' cells.

http://ift.tt/1znL6Cj

Japan's Riken institute definitively dismisses flawed stem cell study

Japan's top research institute has hammered the final nail in the coffin of what was once billed as a ground-breaking stem cell study, dismissing it as flawed and saying the work could have been fabricated. The revelations come a week after a young researcher at the centre of the scandal, which has rocked the country's scientific establishment, said she would resign after failing to reproduce the successful conversion of an adult cell into a stem cell-like state, known as "STAP" cells.

http://ift.tt/1xm5sOa

Immune system may hold key to curing baldness

Somewhat by accident, researchers at Spanish National Cancer Research Centre have discovered a connection between the body's immune system and hair loss - a discovery that could eventually lead to a molecular treatment for baldness. According to a new study in the journal PLOS Biology , immune system cells called macrophages, which gobble up and destroy invading pathogens, have a stimulating effect on skin stem cells and hair growth.

http://ift.tt/1ATffh4

Researchers Sue Brigham, Med School for Alleged Misconduct Investigation

Two stem cell researchers at the Harvard-affiliated Brigham and Women's Hospital have filed a lawsuit against the hospital and Harvard Medical School alleging that an investigation into the researchers' practices by the Medical School and the Brigham is unlawful and damaging to their reputations. Piero Anversa and Annarosa Leri, a professor and associate professor at the Medical School, respectively, who also work at the Brigham, filed the suit against the hospital and the Medical School in federal court on Dec. 16. The researchers alleged that an investigation into their findings on stem cells is damaging to them and should be aimed at their collaborator, Jan Kajstura, formerly an associate professor at the Medical School.

http://ift.tt/1BcNcqG

The science is conclusive: Mobile phones cause cancer

They say there's only two things constant in this life: death and taxes. But a third viable contender might be cancer, which an extensive cohort of scientific research has found is caused by prolonged exposure to radiation from cell phones and their associated communication towers.

http://ift.tt/1EqCWkx

Discredited STAP cells were likely embryonic stem cells

Tying up a loose end of a long-running stem cell research fiasco, yet another RIKEN investigating committee released yet another report in Tokyo today. It concludes that the so-called stimulus-triggered acquisition of pluripotency stem cells, as well as the chimeric mice and teratomas supposedly derived from those cells, "all originated in cultures contaminated with cells, a fact that refutes all of the main conclusions of the two papers" that reported the the supposed breakthrough method of reprogramming adult cells.

http://ift.tt/1vwX7E6

Know More About Caricord cord blood banking Services

... stroke, Parkinson's disease, spinal cord injury and more. PRLog - Dec. 26, 2014 - IRVINE, Calif. -- Stem cell research is now moving at a faster pace even as it is surrounded by ethical controversies and issues. Obtaining stem cells for research ...

http://ift.tt/1CLDqjG

Japan's top research institute dismisses stem cell study

This file photo taken on April 9, 2014 shows Haruko Obokata, a female researcher of Japan's Riken Institute, speaking at a press conference in Osaka, western Japan, following claims that her ground-breaking stem cell study was fabricated. Japan's top research institute on Friday hammered the final nail in the coffin of what was once billed as a ground-breaking stem cell study, dismissing it as flawed and saying the work could have been fabricated.

http://ift.tt/1CWpIHL

Stem Cell Therapy Linked to Recovery of 'Mr. Hockey'

Hockey legend Gordie Howe is making a dramatic recovery from his recent stroke thanks to experimental stem cell therapy developed by San Diego-based Stemedica, his family says. Some medical scientists aren't so sure, though.

http://ift.tt/1ARAyj2

Mathematical models for cellular systems. The von foerster equation. Part II

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. This is the continuation of Part I, which was published in the September, 1965, issue of theBulletin.

http://ift.tt/1ro11md

Leyland woman in remission after decade of hospital treatment

Top Japan lab dismisses ground-breaking...

Japan's top research institute on Friday hammered the final nail in the coffin of what was once billed as a ground-breaking stem cell study, dismissing it as flawed and saying the work could have been fabricated. Haruko Obokata, 31, a researcher at Japan's Riken institute, wipes away tears during a press conference in Osaka, western Japan, on April 9, 2014 The revelations come a week after a young researcher at the centre of the scandal, which has rocked the country's scientific establishment, said she would resign after failing to reproduce the successful conversion of an adult cell into a stem cell-like state, known as "STAP" cells.

http://ift.tt/1AQmeqT

Activating hair growth by modifying immune cells

How to restore hair loss is a task not undertaken exclusively by beauty practitioners. The discover reveals a novel angle to spur hair follicle growth.

http://ift.tt/1wpTO0C

Top Japan lab dismisses ground-breaking stem cell study

Haruko Obokata, 31, a researcher at Japan's Riken institute, wipes away tears during a press conference in Osaka, western Japan, on April 9, 2014 Haruko Obokata, 31, a researcher at Japan's Riken institute, wipes away tears during a press conference in Osaka, western Japan, on April 9, 2014 Japan's top research institute on Friday hammered the final nail in the coffin of what was once billed as a ground-breaking stem cell study, dismissing it as flawed and saying the work could have been fabricated.

http://ift.tt/1zDwvHZ

Top Japan lab dismisses ground-breaking stem cell study

Cellular mechanisms and physiological consequences of redox-dependent signalling.

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Reactive oxygen species , which were originally characterized in terms of their harmful effects on cells and invading microorganisms, are increasingly implicated in various cell fate decisions and signal transduction pathways.

http://ift.tt/1EnqySr

Scientists inject human brain cells into mice, making them 'significantly smarter'

Scientists from the University of Rochester say they have made mice significantly smarter by injecting them at a young age with human brain cells, according to a study published in the journal Cell Stem Cell . The researchers used immature glial cells removed from human fetuses that had been donated for research.

http://ift.tt/1CU7K8S

Did stem cells really help Gordie Howe?

Dr. Murray Howe and his hockey great father, Gordie Howe, on a fishing trip in Saskatchewan in 2013. - Courtesy Murray Howe Hockey legend Gordie Howe is making a dramatic recovery from a serious stroke thanks to stem cell therapy developed by San Diego-based Stemedica, his family says.

http://ift.tt/1xmwVlP

High-fat diet not good in pregnancy

A study has found that high-fat diet and obesity during pregnancy compromise the blood-forming stem cell system in the liver of the developing baby responsible for creating and sustaining lifelong blood and immune system function. "The results offer a model for testing whether the effects of a high-fat diet and obesity can be repaired through dietary intervention, a key question when extrapolating this data to human populations," said Daniel L. Marks, professor of pediatric endocrinology at Oregon-based OHSU's Doernbecher Children's Hospital.

http://ift.tt/1GZCVC4

'STAP cells' claimed by Obokata were likely embryonic stem cells

An investigative panel under the government-backed Riken research institute announced Friday that the so-called STAP stem cells described in the research papers lead-authored by Haruko Obokata were created from embryonic stem cells. The panel "concluded STAP stem cells .

http://ift.tt/1En68cr

Thursday, December 25, 2014

Scientists zero in on how lung cancer spreads

Paralysis cure, new vaginas...and other medical stories of 2014

With a revolutionary new therapy letting a man take his first steps after being paralysed and the deadly Ebola outbreak in West Africa, it has been a year of incredible highs and devastating lows. It has seen hints that HIV is getting milder as well as new vaginas and old wombs being transplanted for the first time.

http://ift.tt/142xTH3

To seek common ground on life's big questions, we need science literacy

Science isn't important only to scientists or those who profess an interest in it. Whether you find fascinating every new discovery reported or you stopped taking science in school as soon as you could, a base level understanding is crucial for modern citizens to ground their engagement in the national conversation about science-related issues.

http://ift.tt/1CHa9GL

Precursors to human sperm, ova created in lab from adult cells

A new research has developed the technique of creating primordial germ cells, which are the embryonic cells that give rise to sperm and ova. The research conducted by Weizmann Institute Of Science explained the cause of fertility problems, yield insight into the earliest stages of embryonic development and potentially, and in future, it would enable the development of new kinds of reproductive technology.

http://ift.tt/1xkVMX7

Top Hair Loss Treatments Make a Futuristic Fight for Your Follicles

There were five of us at the bar that night-all old friends-when I absent-mindedly raked a hand through my hair. Like my father before me, I've always had plenty on top.

http://ift.tt/1x4OOUm

Embracing the complex

It seems there is no question within Halacha that Magazine "Ask the Rabbi" columnist Rabbi Shlomo Brody shies away from discussing in his allotted 800 words. Abortion, infertility, paternity, DNA testing, homosexuality, organ donation, superstition, kol isha , rabbinic ordination for women, fleeing Israel during wartime, stem cell research, conversion, redeeming captive soldiers: the Israel-ordained Orthodox rabbi and Harvard graduate devotes essays to all these provocative topics, and many more in The Jerusalem Post as well as other publications in Israel and his native US.

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RP International founder, Helen Harris Dies on Christmas Eve Just...

Helen Harris passed away on Christmas Eve evening in her home in Woodland Hills California after an 8 year battle with aggressive metastatic breast cancer. As the founder and volunteer President of RP International for over forty years, she pioneered and championed many of today's greatest breakthroughs in restoring and preserving our children's eyesight.

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Stem cells used to create artificial sperm, egg

LONDON: Researchers, led by an Indian-origin scientist, have for the first time used human embryonic stem cells to create primordial germ cells that give rise to egg and sperm. Although this had already been done using rodent stem cells, scientists at the University of Cambridge in UK and the Weizmann Institute in Israel are the first to achieve this feat using human stem cells.

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Novastem uses Stemedica's stem cell products to treat patient in ischemic stroke study

Novastem, a leader in regenerative medicine, announces the treatment of its first patient in its study for ischemic stroke at Clinica Santa Clarita. According to the American Stroke Association, ischemic strokes account for 87 percent of all stroke cases.

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Weight training appears key to controlling belly fat

Healthy men who did 20 minutes of daily weight training had less of an increase in age-related abdominal fat compared with men who spent the same amount of time doing aerobic activities, according to a new study. Combining weight training and aerobic activity led to the most optimal results.

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High-fat diet not good in pregnancy

A study has found that high-fat diet and obesity during pregnancy compromise the blood-forming stem cell system in the liver of the developing baby responsible for creating and sustaining lifelong blood and immune system function. The results offer a model for testing whether the effects of a high-fat diet and obesity can be repaired through dietary intervention, a key question when extrapolating this data to human populations, said Daniel L. Marks, professor of pediatric endocrinology at Oregon-based OHSU's Doernbecher Children's Hospital.

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New technology directly reprograms skin fibroblasts for a new role

As the main component of connective tissue in the body, fibroblasts are the most common type of cell. Taking advantage of that ready availability, scientists from the Perelman School of Medicine at the University of Pennsylvania, the Wistar Institute, Boston University School of Medicine, and New Jersey Institute of Technology have discovered a way to repurpose fibroblasts into functional melanocytes, the body's pigment-producing cells.

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Wednesday, December 24, 2014

Maternal supplementation with multiple micronutrients compared with iron-folic acid

In Bangladesh, daily maternal supplementation of multiple micronutrients compared to iron-folic acid before and after childbirth did not reduce all-cause infant mortality to age 6 months, but did result in significant reductions in preterm birth and low birth weight, according to a study. In Bangladesh, daily maternal supplementation of multiple micronutrients compared to iron-folic acid before and after childbirth did not reduce all-cause infant mortality to age 6 months, but did result in significant reductions in preterm birth and low birth weight, according to a study in the December 24/31 issue of JAMA .

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Researchers map paths to cancer drug resistance

Key events that prompt certain cancer cells to develop resistance to otherwise lethal therapies have been identified by researchers. By mapping the specific steps that cells of melanoma, breast cancer and a blood cancer called myelofibrosis use to become resistant to drugs, the researchers now have much better targets for blocking those pathways and keeping current therapies effective.

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Of mice and men: Researchers point to differences in cell development

An "embryoid" at the start of the appearance of Sox17 positive cells , which depict the birth of the human germ cell lineage. An "embryoid" at the start of the appearance of Sox17 positive cells , which depict the birth of the human germ cell lineage.

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Role of gene mutations involved in more than 75 percent of glioblastomas, melanomas

For the first time, mutations that destabilize a DNA structure that turns a gene off have been discovered by researchers. The mutations occur at four sites in the hTERT promoter in more than 75 percent of glioblastomas and melanomas.

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Some Human Embryonic Stem Cells Are Once Again Patent-eligible in Europe

Last Thursday, the European Court of Justice rendered a decision in International Stem Cell Corporation v. Comptroller General of Patents, Designs and Trademarks that significantly modified the landscape for human embryonic stem cell patenting, by holding that prohibitions against patents on hESCs only apply to such cells derived from embryos that had the potential to develop into a human being.

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Using no-evidence-of-disease-activity standard for patients with multiple sclerosis

Maintaining 'no-evidence-of-disease-activity' was difficult over time for many patients with multiple sclerosis but the measure may help gauge a patient's long-term prognosis, according to a study. Maintaining "no-evidence-of-disease-activity" was difficult over time for many patients with multiple sclerosis but the measure may help gauge a patient's long-term prognosis, according to a study published online by JAMA Neurology .

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Identifying brain variations to predict patient response to surgery for OCD

Identifying brain variations may help physicians predict which patients will respond to a neurosurgical procedure to treat obsessive-compulsive disorder that does not respond to medication or cognitive-behavioral therapies, according to a report. Identifying brain variations may help physicians predict which patients will respond to a neurosurgical procedure to treat obsessive-compulsive disorder that does not respond to medication or cognitive-behavioral therapies, according to a report published online by JAMA Psychiatry .

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Scientists one step closer to creating human egg, sperm

Israeli and British researchers said Wednesday they have successfully used human cells to create primordial germ cells that develop into egg and sperm for the first time. The study, published in the U.S. journal Cell, could help yield insight into fertility problems and early stages of embryonic development and potentially, in the future, enable the development of new kinds of reproductive technology.

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Blocking notch pathway leads to new route to hair cell regeneration to restore hearing

Sensory hair cell loss is the major cause of hearing loss and balance disorders. The postnatal mammalian inner ear harbors progenitor cells which have the potential for hair cell regeneration and hearing recovery, but the mechanisms that control their proliferation and hair cell regeneration are yet to be determined.

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In a First, Weizmann Institute and Cambridge University Scientists...

Groups at the Weizmann Institute of Science and Cambridge University have jointly managed the feat of turning back the clock on human cells to create primordial germ cells - the embryonic cells that give rise to sperm and ova - in the lab. This is the first time that human cells have been programmed into this early developmental stage.

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Children's high risk clinic reduces serious illness by 55 percent

High-risk children with chronic illness who received comprehensive care at a special clinic staffed by physicians and nurse practitioners from The University of Texas Health Science Center at Houston, had a dramatic reduction in serious illnesses, documents a new study. These benefits are the greatest identified to date for medical homes for patients in any age group.

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Identifying brain variations to predict patient response to surgery for OCD

Trends in indoor tanning among U.S. high school students

While indoor tanning has decreased among high school students, about 20 percent of females engaged in indoor tanning at least once during 2013 and about 10 percent of girls frequently engaged in the practice by using an indoor tanning device 10 or more times during the year, according to a research. While indoor tanning has decreased among high school students, about 20 percent of females engaged in indoor tanning at least once during 2013 and about 10 percent of girls frequently engaged in the practice by using an indoor tanning device 10 or more times during the year, according to a research letter published online by JAMA Dermatology .

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High-fat diet, obesity during pregnancy harms stem cells in developing fetus

Popular diabetes drug may be safe for patients with kidney disease

The most popular treatment for type 2 diabetes, metformin, may be safer for patients with mild to moderate kidney disease than guidelines suggest, according to a new, systematic review of the literature. For 20 years, metformin has been used in the U.S. to lower blood sugar in people with type 2 diabetes.

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The heat is on: Causes of hospitalization due to heat waves identified

In the largest and most comprehensive study of heat-related illness to date, researchers have identified a handful of potentially serious disorders that put older Americans at significantly increased risk of winding up in the hospital during periods of extreme heat. In the largest and most comprehensive study of heat-related illness to date, Harvard School of Public Health researchers have identified a handful of potentially serious disorders--including fluid and electrolyte disorders, renal failure, urinary tract infections, sepsis, and heat stroke--that put older Americans at significantly increased risk of winding up in the hospital during periods of extreme heat.

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Novastem Treats First Patient Using Stemedica Cell Technologies,...

According to the American Stroke Association, ischemic strokes account for 87 percent of all stroke cases. Novastem continues to enroll qualified patients in the study, entitled "Internal Research Protocol in Combination Therapy of Intravenous Administration of Allogeneic Mesenchymal Stem Cells and Intrathecal Administration of Neural Stem Cells in Patients with Motor Aphasia due to Ischemic Stroke."

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Cell breakthrough a step toward curing infertility

Scientists at the Weizmann Institute of Science in Rehovot, working with a team at Cambridge University, have successfully created primordial germ cells - the embryonic cells that give rise to sperm and ova - in a test tube. The breakthrough, which scientists have been pursuing for years, according to Dr. Jacob Hanna of the Institute's Molecular Genetics Department, could one day provide a solution for infertile men and women, allowing individuals who have undergone medical traumas like chemotherapy or age-related events such as menopause to once again produce children.

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High-fat diet, obesity during pregnancy harms stem cells in developing fetus

Human Primordial Cells Created in the Lab

High-fat diet, obesity during pregnancy harms stem cells in developing fetus

Gorleston dad's resolution to fight rare disease

Ryan Harman who was diagnosed with motor neurone disease two years ago has been to China for pioneering treatment. pictured at home for Christmas with his parents Dean and Kim.

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In order to cause leukemia, mutations need help from aging tissue

Why are older people at higher risk for developing cancer ? Prevailing opinion holds that, over time, your body's cells accumulate DNA damage and that eventually this damage catches up with the body in a way that causes cancer. A University of Colorado Cancer Center study published in the journal Aging shows that this prevailing opinion is incomplete.

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Tuesday, December 23, 2014

Why Bioethics Should "Fail"

Rejecting the sanctity/equality of human life, utilitarian in outlook, embracing a eugenics point-of-view, the Oxford professor-what does that tell you?-would lead society in a way opposed by most of very people bioethics claims to serve. Savulescu "gets" that the field has not swept all before it-to which I would add, not for lack of trying.

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Stem cells faulty in Duchenne muscular dystrophy, researchers find

Like human patients, mice with a form of Duchenne muscular dystrophy undergo progressive muscle degeneration and accumulate connective tissue as they age. Now, researchers have found that the fault may lie at least partly in the stem cells that surround the muscle fibers.

http://ift.tt/1CyOd0j

The Cell Expansion Market is Expected to Reach $14.8 billion by 2019 -...

North America dominates the cell expansion market with the U.S. accounting for a major market share. Key Players are GE Healthcare , Merck Millipore , Miltenyi Biotec , STEMCELL Technologies , Sigma-Aldrich Corporation , Terumo BCT The report expects global cell isolation and expansion market to grow at 19.7% by 2019.

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Test Predicts Response to Early Treatment for Dangerous Complication...

A new test may reveal which patients will respond to treatment for graft versus host disease , an often life-threatening complication of stem cell transplants used to treat leukemia and other blood disorders, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published online today in the journal Lancet Haematology and in print in the January issue. Patients with fatal blood cancers like leukemia often require allogenic stem cell SCT to survive.

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The vOICe equipment is demonstrated by one user. Photograph: Nic Delves-Broughton/University of Bath

Using sound to help blind people to create images in their heads can prove more effective in enabling them to perform everyday activities, such as picking up a cup or even reading, than invasive surgical operations, according to groundbreaking new research. A joint project involving a team of psychologists and computer scientists at the University of Bath is assessing how the brain can use sensory substitution to help blind and partially sighted people to "see".

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Cretekos reaches blood donation milestone

Tis the season of giving and there may be no greater gift than that of life through blood donation. Clearwater Mayor George Cretekos achieved a milestone in his personal history of giving when he reached the 50 Gallon Donor Milestone at Clearwater OneBlood donor center.

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Genetic study sheds light on how mosquitoes transmit malaria

The genetic sequencing of 16 mosquitoes -- the sole carriers of human malaria -- has been determined by an international team of researchers, providing new insight into how they adapt to humans as primary hosts of the disease. An international research team, including researchers from Simon Fraser University, has determined the genetic sequencing of 16 mosquitoes --the sole carriers of human malaria--providing new insight into how they adapt to humans as primary hosts of the disease.

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Cure For Baldness? Spanish Scientists Use Stem Cells To Restore Hair Growth

In 2014, we are able to restore sight to the blind and hearing to the deaf, but still figuring out a way to reverse hair loss eludes us. Well, 2015 may prove otherwise, as researchers in Spain believe they've found a way to spur new hair growth by using our body's immune defense to stimulate stem cells in the surrounding skin.

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Test predicts response to treatment for complication of leukemia stem cell treatment

A new test may reveal which patients will respond to treatment for graft versus host disease , an often life-threatening complication of stem cell transplants used to treat leukemia and other blood disorders, according to a study. A new test may reveal which patients will respond to treatment for graft versus host disease , an often life-threatening complication of stem cell transplants used to treat leukemia and other blood disorders, according to a study led by researchers at the Icahn School of Medicine at Mount Sinai and published online today in the journal Lancet Haematology and in print in the January issue.

http://ift.tt/1AFeojG

Thirteen-year old cancer survivor to be honored at Rose Bowl

Northwestern Mutual 's Childhood Cancer Program and its nonprofit partner Alex's Lemonade Stand Foundation will honor 13-year old cancer survivor Andrew Sprague for his heroic battle against the disease at the Rose Bowl, Jan. 1. Andrew was diagnosed with leukemia in 2003. He underwent daily chemo, cranial radiation and five surgeries.

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Overweight teens lose weight for the right reasons, study shows

A new study looked at formerly obese or overweight teens who had lost weight and kept it off. Their motives were more intrinisic, such as being healthy and feeling good.

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Way to control internal clocks discovered

Researchers hypothesize that targeting components of the mammalian clock with small molecules like REV-ERB drugs may lead to new treatments for sleep disorders and anxiety disorders. It also is possible that REV-ERB drugs may be leveraged to help in the treatment of addiction.

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CNIO researchers activate hair growth by modifying immune cells

IMAGE: This is a skin whole mount section showing hair follicles surrounded by clusters of skin resident macrophages . The molecular communication between macrophages and hair follicle stem cells regulates... view more How to restore hair loss is a task not undertaken exclusively by beauty practitioners.

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Using targeted brain stimulation to change attention patterns for anxious individuals

Transcranial direct current stimulation is a painless treatment strategy that uses weak electrical currents to deliver targeted stimulation to the brain via electrodes placed on the scalp. tDCS has shown promise in treating mood, anxiety, cognition, and some symptoms of Parkinson's disease.

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Armed virus shows promise as treatment for pancreatic cancer

The study, conducted by a research team from Barts Cancer Institute, Queen Mary University of London, investigated whether the effectiveness of the Vaccinia oncolytic virus - a virus modified to selectively infect and kill cancer cells - as a treatment for pancreatic cancer , would be improved by arming it with a gene which modulates the body's immune system. Despite laboratory studies which show that they can both kill cancer cells and provide immunity against cancer regrowth, oncolytic viruses have not performed well in clinical trials , as the immune system naturally attacks the virus before it can be effective.

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Chimerix, Inc. Provides Recap Of 2014 Events

Chimerix, Inc. , a biopharmaceutical company developing novel, oral antivirals in areas of high unmet medical need, today provided a year-end recap of 2014 highlights for the investigational oral broad-spectrum antiviral brincidofovir. M. Michelle Berrey, M.D., M.P.H., President and CEO of Chimerix, said, "2014 was a pivotal year for brincidofovir and for Chimerix.

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Five Quick Takes on Stem Cells: CIRM, Sanford-Burnham Medical,...

... Evan Snyder, MD, PhD, Professor, Sanford-Burnham Medical Research Institute One of the early pioneers in stem cell research, Evan Snyder is gratified that this technology is finally making its way into FDA-approved trials. For him, it's like ...

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Two Bham biotech firms launch joint venture to boost research

Two Birmingham life sciences companies are teaming up in a bid to boost research initiatives and advance stem cell research. Sacred Cells Research Partners, a spinoff formed in 2013 from research out of the Alabama Institute of Medicine, and Vivo Biosciences, have reached a deal on a new joint venture that company officials say will allow it to compete globally in the biotech industry.

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Reversing Aging Processes with One Protein: a 2014 Breakthrough

The pioneering discovery that young blood-and in particular, a single blood protein called GDF11-can regenerate many organs was named by Science as one of the ten top breakthroughs of 2014. Furthermore, a key group behind the work-Amy Wagers' Harvard University stem cell team-expects to "shortly" identify the human cells that generate GDF11, she told Bioscience Technology in a recent interview.

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Cellular Biomedicine Group Announces Exercise of Stock Options to Purchase Common Stock

Cellular Biomedicine Group, Inc. , a biomedicine firm engaged in the development of effective treatments for degenerative and cancerous diseases, is pleased to announce today that options to purchase an aggregate of 1,000,000 shares of the Company's common stock have been exercised at an exercise price of $8.00 per share, bringing an aggregate of $8,000,000 in exercise proceeds to the Company. The Options were originally issued on July 2, 2014 to investor Francis Leung Pak To, a veteran Hong Kong investment banker.

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Researchers developing a biomedical device that can find and destroy cancer cells

To examine internal organs, doctors often use a tube with light and a tiny camera attached to it. The device, called an endoscope, helps detect cancer and other illnesses.

http://ift.tt/1zZKgj9

Study reveals why older people are at higher risk for developing cancer

Why are older people at higher risk for developing cancer? Prevailing opinion holds that, over time, your body's cells accumulate DNA damage and that eventually this damage catches up with the body in a way that causes cancer. A University of Colorado Cancer Center study published today in the journal Aging shows that this prevailing opinion is incomplete.

http://ift.tt/1xHzTRu

Don't tell me what you believe

... a very socially conservative ideological agenda: opposing abortion, LGBT rights, euthanasia, embryonic stem cell research, and pornography, while supporting public funding for religious organizations. It's a very socially conservative agenda, sure. ...

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In Duchenne muscular dystrophy stem cells found to be faulty

Like human patients, mice with a form of Duchenne muscular dystrophy undergo progressive muscle degeneration and accumulate connective tissue as they age. Now, researchers at the Stanford University School of Medicine have found that the fault may lie at least partly in the stem cells that surround the muscle fibers.

http://ift.tt/13zMKYJ

A Multi-parameter In Vitro Screen in Human Stem Cell-Derived...

Ponatinib, a multi-targeted TKI and potent pan-ABL inhibitor, approved for the treatment of Ph + ALL and CML, was temporarily withdrawn from the U.S. market due to severe vascular adverse events. Cardiac-specific toxicities including myocardial infarction, severe congestive heart failure, and cardiac arrhythmias have also been shown with ponatinib.

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Involvement of Endoplasmic Reticulum Stress in...

866 Yu-Hang-Tang Road, West Lake District, Hangzhou 310058, China. Fax: Excess accumulation of endogenous all- trans -retinal contributes to degeneration of the retinal pigment epithelium and photoreceptor cells, and plays a role in the etiologies of age-related macular degeneration and Stargardt's disease.

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My View: Funding for the future

... and child. At OHSU, NIH funding has allowed us to make medical and scientific breakthroughs in cancer, stem cell research and infectious diseases, among many other areas. With funding from the NIH, Brian Druker, director of the OHSU Knight Cancer ...

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Adult Stem Cell Technology Center, LLC's Director Sherley's...

... his message to congress participants. He gave the address at the 4th World Congress on Cell Science and Stem Cell Research in Valencia, Spain. The international congress was organized by the Omics Group as a part of its mission to foster the ...

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Monday, December 22, 2014

Stem cells born out of indecision

Scientists have gained new insight into embryonic stem cells and how blocking their ability to make choices explains why they stay as stem cells in culture. This research is the first comprehensive analysis of a pathway important for stem and cancer cell decisions known as Erk.

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Elliott Broidy Supports Stem Cell Internships in 2015

PRLog - Dec. 22, 2014 - With the help from the University of Southern California , the Early Investigator High School Program is offering a summer internship opportunity for scientists-to- be in stem cell technology. Elliott Broidy is working with EIHS to fund these scholarships for gifted youth from underprivileged situations to attend the elite summertime internship program.

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NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche

Adult stem cells reside in specialized niches where they receive environmental cues to maintain tissue homeostasis. In mammals, the stem cell niche within hair follicles is home to epithelial hair follicle stem cells and melanocyte stem cells, which sustain cyclical bouts of hair regeneration and pigmentation.

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Test predicts response to treatment for complication of leukemia stem cell treatment

Test Predicts Response to Early Treatment for Dangerous Complication...

New Technique for Bioengineering Stem Cells Shows Promise in HIV...

Using modified human stem cells, a team of UC Davis scientists has developed an improved gene therapy strategy that in animal models shows promise as a functional cure for the human immunodeficiency virus that causes AIDS. Using modified human stem cells, a team of UC Davis scientists has developed an improved gene therapy strategy that in animal models shows promise as a functional cure for the human immunodeficiency virus that causes AIDS.

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European Court of Justice: landmark decision on patentability of stem cells

The European Court of Justice has handed down a landmark judgment concerning the patentability of stem cells in Europe. Stem cells have the potential to revolutionize the treatment of human disease because of their capacity to differentiate into almost any type of adult cell.

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