Randomised, double-blind, placebo-controlled trial of oral budesonide ...

Randomised, double-blind, placebo-controlled trial of oral budesonide for prophylaxis of acute intestinal graft-versus-host disease after allogeneic stem cell transplantation BackgroundGastrointestinal graft?versus-host disease is a potentially life-threatening complication after allogeneic stem cell transplantation . Since therapeutic options are still limited, a prophylactic approach seems to be warranted.MethodsIn this randomised, double-blind-phase III trial, we evaluated the efficacy of budesonide in the prophylaxis of acute intestinal GvHD after SCT.

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