Diagnostic approach to monogenic very early onset IBD

Patients with these disorders often develop symptoms during infancy or early childhood, along with endoscopic or histological features of Crohn's disease, ulcerative colitis, or IBD unclassified. Dr Holm Uhlig and colleagues from the United Kingdom describe key intestinal, extraintestinal, and laboratory features of 50 genetic variants associated with IBD-like intestinal inflammation.

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