Pluripotent cells created by nuclear transfer can prompt immune reaction, researchers find

Stanford researchers find that genetic differences in mitochondria contained in egg cells used in a process known as nuclear transfer can prompt rejection by the immune system in mice. Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell's mitochondria, according to a study in mice by researchers at the S tanford University School of Medicine and colleagues in Germany, England and at MIT.

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