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Saturday, November 1, 2014

Rewiring metabolism slows colorectal cancer growth

Cancers select against a protein complex called the mitochondrial pyruvate carrier , and re-introduction of MPC in colon cancer cells impairs several properties of cancer, including growth. This research implicates changes in a key step in metabolism - the way cellular fuel is utilized - as an important driver of colon cancer that is also likely to be important in many other cancer settings.

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