Transcription factors and chromatin-remodeling complexes are key determinants of embryonic stem cell identity. Here, we demonstrate that BRD4, a member of the bromodomain and extraterminal domain family of epigenetic readers, regulates the self-renewal ability and pluripotency of ESCs.
http://ift.tt/1AJjWYT
http://ift.tt/1AJjWYT
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