A new Yale-led study of children with neurodevelopmental abnormalities of the brain identifies a "cutting" enzyme crucial to the shaping and division of brain cells as well as the replenishment of neural stem cells. The study, appearing online Dec. 17 in the journal Neuron , helps explain the molecular basis of complex brain abnormalities , including small brain size observed in children who were suffering from a wide variety of clinical problems, ranging from severe cognitive deficits to autism spectrum disorders.
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