Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection

Correspondence: H Noguchi, Department of Surgery, Chiba-East National Hospital, National Hospital Organization, 673 Nitona-cho, Chuo-ku, Chiba 260-8712, Japan. Tel: +81 43 261 5171; Fax: +81 43 268 2613; E-mail: n.hirofumi@cehpnet.com or noguchih2006@yahoo.co.jp Although induced pluripotent stem cells have significant implications for overcoming most of the ethical issues associated with embryonic stem cells, there are still several unresolved issues related to the use of iPS cells for clinical applications, such as teratoma formation.

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