Stem Cell Roundup: September 2014

Tuesday, September 30, 2014

The basal epithelial marker P-cadherin associates with breast cancer...

Cancer stem cells are hypoxia-resistant and present a preponderant glycolytic metabolism. These characteristics are also found in basal-like breast carcinomas , which show increased expression of cancer stem cell markers.

http://ift.tt/Zq0Jz1

Global Stem Cells Group Signs Prominent Plastic Surgeon Alfredo Hovos, M.D.

... 305.224.1858. About is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient ...

http://ift.tt/YJH0ZU

Mesoblast Partner JCR Pharmaceuticals Files for Marketing Approval of ...

Regenerative medicine company Mesoblast Limited today reported that its Japanese partner, JCR Pharmaceuticals Co Ltd , has filed with the Japanese Pharmaceuticals and Medical Devices Agency to receive approval for manufacturing, marketing, and product registration of the allogeneic or "off-the-shelf" Mesenchymal Stem Cell product JR-031 for the treatment of acute graft versus host disease in children and adults. The product registration filing by JCR will be subject to a priority review as JR-031 has been granted orphan drug status.

http://ift.tt/1vvlPri

Arigos Biomedical, in the Small Overlap Between Rejuvenation Biotechnology and Cryonics

Within our lifetimes the causes of aging and frailty might be brought under medical control and halted. This goal depends on funding the right research, and we can all do our part: the 2014 matching fundraiser for SENS Research Foundation programs starts on October 1st.

http://ift.tt/1pENnnj

Damaging legacy: Mothers who smoke affect the fertility of their sons

Mothers who smoke while they are pregnant or breast feeding may be damaging the future fertility of their sons, according to new findings from research in mice published online today in Human Reproduction [1], one of the world's leading reproductive medicine journals. The study is the first comprehensive animal model to show the mechanism by which smoking can affect the fertility of male offspring.

http://ift.tt/1pEJfUj

Smoking And Infertility: Mothers Who Smoke While Pregnant Or...

Attention, moms! If you needed another reason to not smoke while pregnant or breastfeeding at this point, here it is. A recent study published in the journal Human Reproduction has revealed that mothers who smoke when they are pregnant or breastfeeding have significantly damaged their son's future fertility.

http://ift.tt/1mNmYcg

Disease decoded: Gene mutation may lead to development of new cancer drugs

The discovery of a gene mutation that causes a rare premature aging disease could lead to the development of drugs that block the rapid, unstoppable cell division that makes cancer so deadly, researchers report. The discovery of a gene mutation that causes a rare premature aging disease could lead to the development of drugs that block the rapid, unstoppable cell division that makes cancer so deadly.

http://ift.tt/1nHgNY2

TAP Biosystems And Gallus Biopharmaceuticals, LLC Co-Host FREE...

... bioprocess development and GMP manufacture of biologics and cell therapies, as well as discovery and stem cell research programmes. Founded in 1987, the company has offices in the UK and USA, and an extensive network of distributors in Europe and ...

http://ift.tt/1qSM3O9

Global Stem Cells Group Signs Prominent

... Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators ...

http://www.prweb.com/releases/GlobalStemCellsGroup/AlfredoHoyosColombia/prweb12211029.htm

Disease Decoded: Gene Mutation May Lead to Development of New Cancer Drugs

The discovery of a gene mutation that causes a rare premature aging disease could lead to the development of drugs that block the rapid, unstoppable cell division that makes cancer so deadly. Scientists at the University of Michigan and the U-M Health System recently discovered a protein mutation that causes the devastating disease dyskeratosis congenita, in which precious hematopoietic stem cells can't regenerate and make new blood.

http://www.newswise.com/articles/view/623977/?sc=rsmn&utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+NewswiseMednews+%28Newswise%3A+MedNews%29

Cellular Biomedicine Group Completes Acquisition Of

Cellular Biomedicine Group Inc. , a biomedicine firm engaged in the development of new treatments for degenerative and cancerous diseases, today announced it has completed the previously announced acquisition of privately held Agreen Biotech Co. Ltd. China and its founder's U.S. patent.

http://ift.tt/1ouSNSF

REGENXBIO's NAV Technology Demonstrates Correction Of...

REGENXBIO Inc. today announced that gene transfer mediated by REGENXBIO's NAVA AAV8 vectors resulted in sustained serum a-L-iduronidase expression, as well as correction of systemic features of MPS I, or Hurler syndrome, a lysosomal storage disease caused by the body's inability to produce the IDUA enzyme. Data from a study performed by researchers at the Perelman School of Medicine at the University of Pennsylvania show animals treated with a single intravenous injection of NAV AAV8 vectors expressing the IDUA gene not only demonstrated meaningful improvements in the biochemical features of MPS I in most tissues, but the majority also exhibited complete resolution of aortic valve lesions.

http://ift.tt/1rAEiA4

Tiziana Life Sciences Plc Release: Interim Results For The Six Months Ended 30 June 2014

A Transformative Year London, 30 September 2014 - Tiziana Life Sciences , a biotechnology company in the fight against metastatic cancers, today announces its interim results for the six months ended 30 June 2014.

http://www.biospace.com/news_story.aspx?StoryID=348344&full=1

Portage Announces Conversion Of Its Debt Into Equity

Portage Biotech Inc. , is pleased to announce that its three Promissory Note holders, two of whom are the directors of Portage, who advanced opted to have their Notes and related Coupons converted into 3,500,001 restricted common shares. Notes were repayable within one year and carried 5% coupon.

http://www.biospace.com/news_story.aspx?StoryID=348288&full=1

Disease decoded: Gene mutation may lead to development of new cancer drugs

The discovery of a gene mutation that causes a rare premature aging disease could lead to the development of drugs that block the rapid, unstoppable cell division that makes cancer so deadly. Scientists at the University of Michigan and the U-M Health System recently discovered a protein mutation that causes the devastating disease dyskeratosis congenita, in which precious hematopoietic stem cells can't regenerate and make new blood.

http://ift.tt/1ovhvSI

Analysts differ on Seattle Genetics outlook after data

Seattle Genetics downgraded at BofA/Merrill As previously reported, BofA/Merrill downgraded Seattle Genetics to Underperform from Neutral. The firm said AETHERA data for interim overall survival advantage was not significant and could reinforce Adcetris' role as a salvage therapy as opposed to a frontline option.

http://ift.tt/1wUUZrD

We won't drop food and safety standards for TTIP, Andriukaitis tells MEPs

... the cloning of animals for human consumption and labelling of clone-containing food, EU funding for human stem cell research and cross-border risks of GMO cultivation, he said. He said he was open the idea of new rules, especially for issues he ...

http://ift.tt/ZoghmK

Living with a Disability Magazine Marks National Sickle Cell Health...

To mark National Sickle Cell Month which occurs every September, the Editorial Board of Living with a Disability magazine has published an important new article that sheds light on hematological disorders as disabling conditions. To mark National Sickle Cell Month which occurs every September, the Editorial Board of Living with a Disability magazine has published an important new article that sheds light on hematological disorders as disabling conditions.

http://ift.tt/1rIC03E

Cellular Biomedicine Group Completes Acquisition of Agreen Biotech Co Ltd.

AG's IP is comprised of T Cells Receptor clonality analysis technology and T Central Memory Cell and Dendritic Cell preparation methodologies. The TCR clonality analysis technology is based on the use of multiple sets of unique primers to amplify 22 regions of the TCR, thereby detecting clonal expansions related to antigen stimulation of the immune system, which enables the assessment of tumor specific immunity with high accuracy and efficiency.

http://ift.tt/YNE2TX

Humacyte's Dr. Laura Niklason to Speak at Alliance for Regenerative Medicine Conference

Humacyte, a pioneering biotechnology firm, announced today that Humacyte founder, Laura Niklason, M.D., Ph.D., will be a keynote speaker at the 9th Annual Stem Cell Meeting on the Mesa presented by the Alliance for Regenerative Medicine . The Stem Cell Meeting on the Mesa is a three-day conference that brings together senior executives and top decision-makers in the regenerative medicine and advanced therapies industry with the scientific community to advance cutting-edge research into cures.

http://ift.tt/1rIBXVv

CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem...

Tianhe is performing Phase I/II clinical trials in using Tianhe's Stem Cell Educator Therapy showing that the therapy is safe. In patients with moderate or severe Type 1 Diabetes , a single treatment produced lasting improvement in metabolic control.

http://ift.tt/1vtLzo1

CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem...

CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases /PRNewswire/ -- CORD:USE Cord Blood Bank - www.corduse.com - is pleased to announce that it has entered into an Equity and Exclusive Services Agreement with TianheA Stem Cell Biotechnologies, Inc. which has licensedA a series of patented technologies for the isolation of human cord blood-derived multipotent stem cells for possible clinical applications.A Tianhe is performing Phase I/II clinical trials in using Tianhe's Stem Cell Educator ... (more)

http://ift.tt/1rIoUmI

Humacytea s Dr. Laura Niklason to Speak at Alliance for Regenerative Medicine Conference

Insider Buying: Brainstorm Cell Therapeutics major shareholder Buys 11,000 Shares of Stock

Brainstorm Cell Therapeutics major shareholder International Holdings Ltd Acc bought 11,000 shares of the company's stock in a transaction that occurred on Monday, September 22nd. The shares were purchased at an average price of $4.17 per share, for a total transaction of $45,870.00.

http://ift.tt/1vrPzU0

Humacyte's Dr. Laura Niklason to Speak at Alliance for Regenerative Medicine Conference

The Stem Cell Meeting on the Mesa is a three-day conference that brings together senior executives and top decision-makers in the regenerative medicine and advanced therapies industry with the scientific community to advance cutting-edge research into cures. The conference will take place in in Biomedical Engineering and Anesthesia, and also serves as Vice-Chair for Anesthesia at Yale.

http://ift.tt/1vrPzDE

Cedars-Sinai Certified by ALS Association as Center of Excellence for Treatment, Research

The ALS Program at Cedars-Sinai has become the first in Southern California to be named an ALS Association Certified Treatment Center of Excellence - a distinction that recognizes the quality of its treatment and research programs for patients with Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS. The progressive disease attacks neurons in the brain and spinal cord that control muscles throughout the body.

http://ift.tt/ZnVoIs

Seattle Genetics outlook still positive, says RBC Capital

Breakthrough could prevent hip implant replacement

Hip implants rely on the normal functioning of bone cells to achieve fixation of the implant with the bone. However, small metal particles released from hip implants, due to friction between the moving surfaces, have been shown to be toxic to the surrounding bone cells.

http://ift.tt/1wTXzhB

BrainStorm Completes Uplisting to the NASDAQ Capital Market

BCLI), a leading developer of adult stem cell technologies for neurodegenerative diseases, today announced that its shares of common stock have been approved for to the NASDAQ Capital Market, and will commence trading on the NASDAQ Capital Market when trading begins on September 30, 2014. previous announcement that from September 16, 2014 until October 14, 2014 their shares would be quoted as "BCLID" in order to designate the recent one for fifteen reverse split of Cell Therapeutics Inc. is a biotechnology company engaged in the development of first-of-its-kind adult stem cell therapies derived from autologous bone marrow cells for the treatment of neurodegenerative diseases.

http://ift.tt/1pnQm4y

Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology

His interest, expertise, and research in stem cell toxicology began when he joined the faculty of the Toxicology Division at the for the National Toxicology Program from 2008 to 2011. Drug development success depends on two main drug attributes, safety and efficacy.

http://ift.tt/1pnOLvl

BrainStorm Completes Uplisting to the NASDAQ Capital Market

"We are so happy to bring BrainStorm's common stock to NASDAQ. This is an important step in BrainStorm's corporate development.

http://ift.tt/1pnOIzQ

Rainbow Scientific, Inc. opens online store for state-of-the-art stem ...

The online store also offers classical tissue culture media, serum and animal component free culture media, human cytogenetic reagents, disinfectants, mycoplasma elimination and detection products, and a one-step cell proliferation kit. "We are pleased to offer our customers the convenience of 24/7 online ordering, while continuing the personalized service and superior support that is a hallmark of doing business with RSI", says has been a North American distributor of state-of-the-art products and solutions to academic, government, clinical and biotechnology laboratories for over seventeen years.

http://ift.tt/1pnOLeR

Correction of cardiovascular symptoms of MPS I in animal model

REGENXBIO Inc. today announced that gene transfer mediated by REGENXBIO's NAV AAV8 vectors resulted in sustained serum I -L-iduronidase expression, as well as correction of systemic features of MPS I, or Hurler syndrome, a lysosomal storage disease caused by the body's inability to produce the IDUA enzyme. Data from a study performed by researchers at the Perelman School of Medicine at the University of Pennsylvania show animals treated with a single intravenous injection of NAV AAV8 vectors expressing the IDUA gene not only demonstrated meaningful improvements in the biochemical features of MPS I in most tissues, but the majority also exhibited complete resolution of aortic valve lesions.

http://ift.tt/1rHvB8B

Rainbow Scientific, Inc. opens online store for state-of-the-art stem ...

Now customers have the convenience of 24/7 online ordering with the personalized service and superior support that is a hallmark of RSI. Rainbow Scientific, Inc. , a North American distributor of scientific research products, recently opened an online store to add customer convenience in ordering its comprehensive cell culture product lines developed and manufactured by Biological Industries, Inc. Products available through its online store include Biological Industries' Nutristem serum-free, xeno-free reagents for human mesenchymal stem cell and human embryonic stem cell culture.

http://ift.tt/1wToNF4

Adult Stem Cell Technology Center, LLC Director James L. Sherley Discusses Stem Cell Toxicology

In a recent online interview by the Pharma IQ Division of the International Quality & Productivity Center , James L. Sherley, M.D., Ph.D., the Director of the Adult Stem Cell Technology Center, LLC discussed the state of technology for drug evaluations for stem cell toxicity. As an expert on the topic, Dr. Sherley emphasized that, currently, few technologies exist for screening-out drug candidates that will ultimately fail as medicines due to toxicity against stem cells in the body.

http://ift.tt/1wToMAV

Asterias Biotherapeutics Signs Pact with Cancer Research UK and Cancer Research Technology

According to a media release, AST-VAC2 is a non-patient specific cancer vaccine designed to stimulate patients' immune systems to attack telomerase, a protein that is expressed in over 95 percent of cancers but is rarely expressed in normal adult cells. The vaccine was developed following successful early phase clinical trials of a similar, patient specific Asterias vaccine, called AST-VAC1, which was derived from patients' blood cells and tested in prostate cancer and acute myeloid leukemia.

http://ift.tt/1ryGPe6

Monday, September 29, 2014

A Better Understanding of the Mechanisms of ALT, Alternative Lengthening of Telomeres

Acute Myeloid Leukemia and Myelodysplastic Syndromes in Older Adults.

Treatment of older adults with acute myeloid leukemia or myelodysplastic syndromes is challenging because of disease morbidity and associated treatments. Both diseases represent a genetically heterogeneous group of disorders primarily affecting older adults, with treatment strategies ranging from supportive care to hematopoietic stem-cell transplantation.

http://ift.tt/1rowSCp

Experts discover shining cells responsible for developing tumors

Researchers Bruno Sainz and Irene Miranda show the image of a tumor stem cell containing green-colored fluorescent vesicles. Credit: CNIO Tumours are mosaics of cells that are morphologically and molecularly very different.

http://ift.tt/1xuzeSy

Big Data May Help Provide a "Global View" of Neuromuscular Disorders

A National Institutes of Health grant presented to investigators at the Cedars-Sinai Regenerative Medicine Institute is intended support Cedars-Sinai's participation in a consortium focused on gathering and analyzing data to provide a "global view" of neuromuscular disorders.

http://ift.tt/1wS9Sen

Cord Blood Stem Cells Increased Tenfold

The potential advance was made via a little-known pyrimidoindole molecule called UM171. Tested by the team of University of Montreal investigator Guy Sauvageau, UM171 may dramatically reduce blood stem cell transplant complications, and considerably increase patient access to the procedure.

http://ift.tt/10g3MJZ

Advanced Cell Technology And Dilution: Do We Really Have A Rational Choice?

A reverse split with a proxy for dilution, without the ability to uplist, is usually bad juju, and this is why shareholders are concerned. Advanced Cell Technology is a cutting edge stem cell biotech company currently finishing Phase I trails for Macular Degeneration .

http://ift.tt/1vqAofL

Reprogramming Fibroblasts to Endothelial Cells: Converted or Born Again? [Editorials]

From the Section of Cardiology, Department of Medicine , and Department of Pharmacology , University of Illinois at Chicago, College of Medicine, Chicago. Correspondence to Jalees Rehman, MD, Department of Medicine, Section of Cardiology and Department of Pharmacology, University of Illinois at Chicago, College of Medicine , 835 S Wolcott Ave, Room E403, Chicago, IL 60612.

http://ift.tt/1nBkwq3

Direct Conversion of Adult Skin Fibroblasts to Endothelial Cells by...

From National Research Laboratory for Cardiovascular Stem Cell, Seoul National University College of Medicine, Seoul, Republic of Korea ; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea ; Center for Vascular Biology Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA ; and Molecular Medicine & Biopharmaceutical Sciences, Seoul National University, Seoul, Republic of Korea . Correspondence to Hyo-Soo Kim, MD, Molecular Medicine and Biopharmaceutical Sciences, Seoul National University, 101 Daehak-ro, Jongro-gu, Seoul 110-744, Republic of Korea.

http://ift.tt/1uX4AwG

Study holds hope of a treatment for deadly genetic disease, MPS Iiib

Dr. Patricia I. Dickson is the director of the LA BioMed MPS Research Lab where a new study holds hope for treating patients with MPSIIIB. Credit: LA BioMed MPS IIIB is a devastating and currently untreatable disease that causes progressive damage to the brain, leading to profound intellectual disability, dementia and death-often before reaching adulthood.

http://ift.tt/1wRIJbq

National Sickle Cell Disease Awareness Month

September is National Sickle Cell Awareness Month, and while there are very few who know about the disease, there are approximately 100,000 people suffering with the condition in the United States alone. There are serious health problems associated with the disease that warrant more awareness that could be prevented with careful screening and simple blood tests.

http://ift.tt/1nBh3Ys

Laang locals rally for diabetes walk for 12-year-old Ella Pattison

Twelve-year-old Ella Pattison with organiser Brooke Dean, who has the Laang community registered as a team to take part in the Walk to Cure Diabetes and raise money for research. Picture: AARON SAWALL Banding together in support for 12-year-old Ella Pattison, Laang residents will take on the Juvenile Diabetes Research Foundation's Walk to Cure Diabetes in Warrnambool on Sunday.

http://ift.tt/1uWN6QU

Cancer Treatment Institute of Colombia Demonstrates Unprecedented...

Cancer Treatment Institute of Colombia Demonstrates Unprecedented Results Using Unique Cancer Drug Combination of 3-Bromopyruvate and Salinomycin for Treatment of Multiple Types of Cancer has announced a promising new drug treatment: a carefully formulated, first-of-its-kind combination of salinomycin and 3-bromopyruvate that has already proven successful at treating multiple types of cancer. The team of medical researchers behind this novel treatment are optimistic that it could significantly improve outcomes for many patients who have exhausted current therapeutic avenues.

http://ift.tt/1xuu753

Graft-Versus-Host Disease - Opportunity Analysis and Forecasts to 2018

Summary The main drivers of growth in graft versus host disease over the 2013-2018 forecast period include the increasing numbers of allogeneic hematopoietic stem cell transplants and the increasing use of biologic off-label and marketed therapies in the 6MM. Sanofi is a key player in the GVHD market with Thymoglobuline and Lemtrada by infiltrating prophylaxis, aGVHD and cGVHD.

http://ift.tt/1uWJrm4

NeoStem, Inc. Secures Debt Facility

NeoStem, Inc. , a leader in the emerging cellular therapy industry, announced today that it has entered into a Loan and Security Agreement with Oxford Finance LLC pursuant to which Oxford has agreed to make a term loan to the Company in the principal amount of up to $20 million, and has made the initial disbursement of $15 million. The loan matures in September 2018 and the additional $5 million disbursement is available in the event of the Company's consummation of a partnering transaction around the Company's NBS10 development program for post acute myocardial infarction patients.

http://ift.tt/10f2mj9

Cancer Treatment Institute Of Colombia Demonstrates Unprecedented...

The team of medical researchers behind this novel treatment are optimistic that it could significantly improve outcomes for many patients who have exhausted current therapeutic avenues. "These two drugs are exceptional on their own, but it's their combination that's proving to be instrumental," explained Dr. , part of the team overseeing the current project.

http://ift.tt/1xuj4IV

Applied Genetic Technologies Corporation Leadership To Present At Upcoming Healthcare Conferences

Applied Genetic Technologies Corporation , a clinical stage biotechnology company developing adeno-associated virus -based gene therapies for the treatment of rare eye diseases, today announced that company management will present at two upcoming conferences. Targeting Ocular Disorders on Tuesday, October 7, 2014 at 1:55pm ET in Boston.

http://ift.tt/10f2nUe

Turmeric compound boosts regeneration of brain stem cells

... and differentiation in the brain, reveals new research published today in the open access journal Stem Cell Research & Therapy . The findings suggest aromatic turmerone could be a future drug candidate for treating neurological disorders, such as ...

http://ift.tt/10f2kYv

Seattle Genetics, Inc. And Takeda Pharmaceutical Co. Ltd. Announce...

BOTHELL, Wash. & OSAKA, Japan-- --Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited today announced that patients with Hodgkin lymphoma who received ADCETRIS as consolidation therapy immediately following an autologous stem cell transplantation lived significantly longer without disease progression compared to patients who received placebo.

http://ift.tt/1nAEh0Q

Bionomics Limited Presents BNC105 Phase 2 Renal Cancer Trial Biomarker Data

Bionomics Limited today presented new important data from the DisrupTOR-1 trial of BNC105 in patients with metastatic renal cancer at the European Society for Medical Oncology congress in Madrid, Spain. The data, presented by Dr Sumanta Pal, of the City of Hope Comprehensive Cancer Center in Duarte, CA, USA, emphasizes the plasma biomarker profile associated with favourable outcomes for patients treated with BNC105.

http://ift.tt/1nAEgKa

Portage announces conversion of its debt into equity

NAPSR News: Daiichi-Sankyo will Acquire Ambit Biosciences

PRLog - Sep. 29, 2014 - WASHINGTON, D.C. -- Daiichi Sankyo Company Ltd and Ambit Biosciences, a U.S. based biopharmaceutical company, have announced their plans to enter into a definitive merger agreement. Daiichi Sankyo will be acquiring all outstanding common stock of Ambit Biosciences for $15 per share in cash through a tender offer.

http://ift.tt/1nAjcDQ

InVivo Therapeutics Announces Appointment of Daniel R. Marshak, PhD to Its Board of Directors

... served as Senior Vice President and Chief Scientific Officer for Osiris Therapeutics, Inc., where he led stem cell research and development from inception to late-stage clinical trials. Before working at Osiris, he was a Senior Staff Investigator at ...

http://www.hispanicbusiness.com/2014/9/29/invivo_therapeutics_announces_appointment_of_daniel.htm

Seattle Genetics positive data largely as expected, says Piper Jaffray

Seattle Genetics weakness a buying opportunity, says Credit Suisse Credit Suisse said Seattle Genetics top-line AETHERA data was significantly positive for the primary endpoint and expects full results in December at ASH to provide a meaningful update. The firm would use weakness as a buying opportunity and reiterates its Outperform rating and $51 price target.

http://ift.tt/1rycA8e

Seattle Genetics, Takeda's cancer drug meets main goal in trial

Seattle Genetics Inc and Takeda Pharmaceutical Co Ltd said their approved cancer drug was successfully used as a consolidation therapy in a late-stage trial for patients with a type of lymphatic cancer. Consolidation therapy is given to cancer patients who have undergone initial therapy and kills any cancer cells that may be left in the body.

http://ift.tt/1rycwWi

Minnesota's First Openly Transgender Candidate Paula Overby Releases Campaign Video - WATCH

... oted to repeal Obamacare fifty-four times and is against - among other things - raising the minimum wage, stem cell research, same-sex marriage and funding for climate change studies.

http://ift.tt/1nzF7e9

Researchers working to regenerate heart, nerve cells

... in the embryo and how that goes awry in human disease," says Srivastava, who now directs cardiac and stem cell research at the Gladstone Institutes and is a professor at the University of California San Francisco. The two went on to discover many of ...

http://ift.tt/10dW4Af

Scientists identify signature of aging in the brain

An immunofluorescence microscope image of the choroid plexus. Epithelial cells are in green and chemokine proteins are in red Credit: Weizmann Institute of Science How the brain ages is still largely an open question - in part because this organ is mostly insulated from direct contact with other systems in the body, including the blood and immune systems.

http://ift.tt/1BvJesq

Scientists Seen As Competent But Not Trusted By Americans

The review , published in the Proceedings of the National Academy of Sciences , shows that while Americans view scientists as competent, they are not entirely trusted . This may be because they are not perceived to be friendly or warm.

http://ift.tt/1oqthhm

Cells from placentas safe for patients with multiple sclerosis

Patients with Multiple Sclerosis were able to safely tolerate treatment with cells cultured from human placental tissue, according to a study published today in the journal Multiple Sclerosis and Related Disorders . The study, which is the first of its kind, was conducted by researchers at Mount Sinai, Celgene Cellular Therapeutics subsidiary of Celgene Corporation and collaborators at several other institutions.

http://ift.tt/1voGdtY

Seattle Genetics Seeks Expanded Use of Lymphoma Drug Following Study Win

Your browser is not supported. Please upgrade to one of the following browsers: Google Chrome Mozilla Firefox Apple Safari Microsoft Internet Explorer 8+ You may proceed to the site by clicking here , however some pages might not work correctly.

http://ift.tt/1nzCwkD

Seattle Genetics, Inc., Takeda Pharmaceutical Co. Ltd.'s Cancer Drug...

Seattle Genetics and Takeda Announce Positive Data from Phase 3 AETHERA Clinical Trial of ADCETRISA for Consolidation in Post-Transplant Hodgkin Lymphoma Randomized Phase 3 Clinical Trial with ADCETRIS Demonstrates Statistically Significant Improvement in Progression-Free Survival Abstract Submitted to ASH for Presentation at the 2014 Annual Meeting; Regulatory Submissions Anticipated in 2015 Seattle Genetics to Host Conference Call and Webcast Today at 8:30 a.m. ET BOTHELL, Wash.

http://ift.tt/YBPzWI

Seattle Genetics Seeks Expanded Use of Lymphoma Drug Following Study Win

Morici: 5 Forces That Will Shape the 21st Century

... work into our late 70s and make life more productive and rewarding for longer. Breakthroughs in DNA and stem cell research will make organ replacement and enhancement routine. A more durable and intelligent human race will be reality, not science ...

http://ift.tt/YFZNoH

InVivo Therapeutics Announces Appointment of Daniel R. Marshak, PhD to Its Board of Directors

... served as Senior Vice President and Chief Scientific Officer for Osiris Therapeutics, Inc., where he led stem cell research and development from inception to late-stage clinical trials. Before working at Osiris, he was a Senior Staff Investigator at ...

http://www.freshnews.com/news/992739/invivo-therapeutics-announces-appointment-daniel-r-marshak-phd-its-board-directors

UPDATE 1-Seattle Genetics and Takeda's cancer drug meets main trial goal

Seattle Genetics Inc and Takeda Pharmaceutical Co Ltd said their approved cancer drug was successfully used as a consolidation therapy in a late-stage trial for patients with a type of lymphatic cancer. Patients who received the drug, Adcetris, immediately after a stem cell transplant, lived significantly longer without the disease progressing than those who were given a placebo, the companies said in a joint statement.

http://ift.tt/1DR9MIy

European Medicines Agency Validates the Marketing Authorization...

"We are pleased to have two applications for nivolumab now under review in the E.U., and look forward to continued collaboration with health authorities around the world as we work to bring nivolumab to patients." "Lung cancer is the leading cause of cancer death worldwide, and there remains a significant need for effective treatment options for patients with this disease," said Michael Giordano, M.D., senior vice president, Head of Oncology Development, Bristol-Myers Squibb.

http://ift.tt/YFOm0i

DNA Sequencing Kit generates ChIP-seq libraries for NGS.

September 29, 2014 - In DNA SMART ChIP-Seq Kit, adaptation of template switching technology is used to add Illumina -specific adapters directly to DNA. This produces ChIP-seq libraries without additional ligation or clean-up steps.

http://ift.tt/YFOixE

Bengals will donate more than $1M from jersey sales

The Cincinnati Bengals announced this weekend that more than 10,000 Devon Still jerseys have been sold in the last two weeks.

http://ift.tt/YFOk8B

NeoStem Secures Debt Facility

Bionomics Presents BNC105 Phase II Renal Cancer Trial Biomarker Data

Seattle Genetics and Takeda Announce Positive Data from Phase 3...

Seattle Genetics and Takeda Announce Positive Data from Phase 3 AETHERA Clinical Trial of ADCETRIS A for Consolidation in Post-Transplant Hodgkin Lymphoma BOTHELL, Wash. & OSAKA, Japan-- -- Seattle Genetics, Inc. and Takeda Pharmaceutical Company Limited today announced that patients with Hodgkin lymphoma who received ADCETRIS as consolidation therapy immediately following an autologous stem cell transplantation lived significantly longer without disease progression compared to patients who received placebo.

http://ift.tt/YFOcpC

Susy Gage Releases New Medical Thriller, not Easy Being Green

Smallpox virus found sitting in a corner. An infected mouse sending researchers scurrying.

http://ift.tt/1DR9G3N

Researchers show irradiation plus transplantation effective for treating HIV/AIDS

Yerkes National Primate Research Center researchers are the first to show that an irradiation plus transplantation combination approach in nonhuman primates can be used to treat or even possibly cure HIV/AIDS, and this new model is providing some answers about the "Berlin patient," the only human thought cured of AIDS. The study is published in the September 25 issue of PLOS Pathogens .

http://ift.tt/1qNSCRV

Seattle Genetics, Takeda announce positive data from Phase 3 trial of Adcetris

Seattle Genetics, Takeda announce positive data from Phase 3 trial of Adcetris Seattle Genetics and Takeda Pharmaceutical announced that patients with Hodgkin lymphoma who received ADCETRIS as consolidation therapy immediately following an autologous stem cell transplantation lived significantly longer without disease progression compared to patients who received placebo. The phase 3 clinical trial, known as AETHERA, compared the use of single agent ADCETRIS to placebo in 329 patients with HL who were at risk of relapse.

http://ift.tt/YFO9KA

'Hey, Where's My Smallpox?': Susy Gage's New Medical Thriller ...

"Not Easy Being Green," the second in Susy Gage's lab-lit series from Bitingduck Press, explores timely issues in biomedical research. From fraud to untested therapies to carelessness with hot agents, the book takes the reader on an insider's tour of a high-pressure bio lab.

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Curry spice - helps brain self- heal'

A spice commonly found in curries may boost the brain's ability to heal itself, according to a report in the journal Stem Cell Research and Therapy. The German study suggests a compound found in turmeric could encourage the growth of nerve cells thought to be part of the brain's repair kit.

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Key factor that maintains stem cell identity found

A protein implicated in several cancers appears to play a pivotal role in keeping stem cells in an immature "pluripotent" state, according to a new study. Stem cells are the perpetual adolescents of the cellular world, uncommitted to any cell fate.

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Sunday, September 28, 2014

Can eating curry 'help beat dementia?'

Spicy food has always had hidden health benefits. Now, devotees of spicy Indian food could be better equipped to ward off dementia, research suggests.

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Modulation of Neurogenesis by targeting Epigenetic Enzymes using Small Molecules: An overview.

Neurogenesis consists of a plethora of complex cellular processes including neural stem cell proliferation, migration, maturation or differentiation to neurons, and finally integration into the pre-existing neural circuits in the brain, which are temporally regulated and coordinated sequentially. Mammalian neurogenesis begins during embryonic development and continues in postnatal brain .

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Devon Still jersey sales raise major bucks for children's hospital

The Cincinnati Bengals get a gold star this week for good behavior. The Bengals are three weeks into its fundraiser for pediatric cancer research and they have some big news.

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Human Evolution Was Driven By The Genetic Mutations And The Genes That Repressed Them

Humans came to be after millions of years of conflict between genes that mutated and those that repressed their mutation. "We have basically the same 20,000 protein-coding genes as a frog, yet our genome is much more complicated, with more layers of gene regulation," said Sophie Salama, a research associate at the University of California, Santa Cruz, Genomics Institute, where researchers are studying the complex processes of human evolution.

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In Search Of A Cure For HIV: Researchers Replicate Treatment Of The...

Scientists have worked frantically since the 1980s to develop a cure for HIV/AIDS. In the years since, they developed antiretroviral therapy , the most effective treatment for the range of disease, which bolsters the body's immune by suppressing the virus' ability to replicate.

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[Herald Review] Exploring blurred line between truth and national interest

... an informant confessing that research by Dr. Lee Jang-hwan, a feted national figure on account of his stem cell research, is based on fabricated data. The informant, identified as Shim Min-ho (Yoo Yeon-seok), decides to expose Lee's misconduct after ...

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Kidney regeneration and stem cells.

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. The kidney has the capacity to recover from ischemic and toxic insults.

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Regeneration of brain stem cells boosted by turmeric compound

A bioactive compound found in turmeric promotes stem cell proliferation and differentiation in the brain, reveals new research published in the open access journal Stem Cell Research & Therapy. The findings suggest aromatic turmerone could be a future drug candidate for treating neurological disorders, such as stroke and Alzheimer's disease .

http://ift.tt/1qIVQGi

In new primate model, stem cell transplant does not cure SHIV/AIDS after irradiation

A study published in PLOS Pathogens reports a new primate model to test treatments that might cure HIV/AIDS and suggests answers to questions raised by the "Berlin patient", the only human thought to have been cured so far. Being HIV-positive and having developed leukemia , the Berlin patient underwent irradiation followed by a bone-marrow transplant from a donor with a mutation that abolishes the function of the CCR5 gene.

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Saturday, September 27, 2014

Sniffing out clues in Down syndrome

Was that what fuelled your interest in Down syndrome? Yes. During that process, I became very intrigued in this complex phenomenon known as Down syndrome, and realised how frequent and prevalent it is.

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In brief

... that play a crucial role in helping the brain to heal itself. The findings, published in the journal Stem Cell Research And Therapy, suggest that the compound - aromatic turmerone (ar-turmerone) - could hold the key to treating neurological ...

http://ift.tt/1sEukkP

Vietnam opens free stem cell bank

Umbilical cord blood is stored at a community stem cell bank at the Central Hematology and Blood Transfusion Institute in Hanoi. Photo: Duong Ngoc The Central Institute of Hematology and Blood Transfusion began developing the bank in May in cooperation with Hanoi's Ob-Gyn Hospital.

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Common Curry Ingredient Could Help The Brain...

Eating spicy Indian food could help boost the brain's ability to heal itself, according to new research published in Friday's edition of the journal Stem Cell Research and Therapy . According to Damian Gayle of The Daily Mail , aromatic turmerone, a compound found in the popular curry spice turmeric, could encourage the growth of nerve cells believed to help repair the brains of those suffering from neurodegenerative conditions such as dementia or Alzheimer's disease .

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Taking the fight to forgotten cancers

THEY might be generations apart but a love of classic cars and the Bay to Birdwood is a bonding exercise for Nigel Steele Scott and his 17-year-old granddaughter Julia. WHILE most of us are still thinking about punching the clock, the Eyre Peninsula's abalone divers are punching into the swells of the Southern Ocean.

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Stem cell transplant does not cure SHIV/AIDS after irradiation of infected rhesus macaques

A new primate model has been developed to test treatments that might cure HIV/AIDS and suggests answers to questions raised by the 'Berlin patient,' the only human thought to have been cured so far. A study published on September 25th in PLOS Pathogens reports a new primate model to test treatments that might cure HIV/AIDS and suggests answers to questions raised by the "Berlin patient," the only human thought to have been cured so far.

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How stem cells help cure diseases

Stem cells are the body's natural healing cells. They are used by human tissues to repair and regenerate damaged cells.

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High-throughput cell-sorting method can separate 10 billion bacterial cells in 30 minutes

A new, high-throughput method for sorting cells has been developed, capable of separating 10 billion bacterial cells in 30 minutes. The finding has already proven useful for studying bacterial cells and microalgae, and could one day have direct applications for biomedical research and environmental science -- basically any field in which a large quantity of microbial samples need to be processed.

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Humble turmeric may treat neurological disorders

... or its anti-inflammatory and neuroprotective properties. The research appeared in the open access journal Stem Cell Research & Therapy.

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Tenure Track Faculty Positions

As part of a major expansion, the Department of Genetics is now recruiting investigators at all academic levels. Individuals with expertise in high-throughput functional genomics, including single-cell analysis; computational and systems biology; development of cellular and animal models of human disease; stem cell biology; genome engineering; epigenomics and analysis of gene-environment interactions; or novel strategies to evaluate the role of genetic variants in disease etiology, are encouraged to apply.

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Postdoctoral Fellow in Computational Systems Biology at the Luxembourg Centre for Systems Biomedicine

The is an Interdisciplinary Centre of the University, independent of the faculties and it combines experimental and computational approaches to analyze complex biological systems and disease processes from a systems biology perspective.

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Friday, September 26, 2014

Turmeric compound boosts regeneration of brain stem cells

Michigan bone marrow recipient meets her donor

Michigan bone marrow recipient meets her donor Jessie Kelly wanted to honor the woman who saved her life by contributing her stem cells. Check out this story on battlecreekenquirer.com: http://on.lsj.com/1szSa1a In this photo taken on Sept.

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SENS Research Foundation Newsletter, September 2014

Scientists use stem cells to learn how common mutation in Asians affects heart health

Researchers studied heart muscle cells derived from pluripotent stem cells to find out why a genetic mutation common in East Asians leads to an increased risk of heart disease. Over 500 million people worldwide carry a genetic mutation that disables a common metabolic protein called ALDH2.

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High-dose chemotherapy for germ cell tumors: do we have a model?

Introduction: Since the late nineties, the intensification of chemotherapy doses with hematopoietic stem cell rescue held promise for patients with advanced and poor prognosis germ cell tumors . High-dose chemotherapy has, nowadays, a recognized indication in the salvage setting of advanced GCTs and is steadily utilized worldwide.Areas covered: We evaluated the available data with the use of HDCT in these patients.

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Spice Shows Promise Against Alzheimer's

... from stroke and Alzheimer's disease, Medical News today reports. The study, published in the journal Stem Cell Research & Therapy , found that the bioactive compound found in the spice is called aromatic (ar-) turmerone, and previous studies have ...

http://ift.tt/1qDYi0X

Turmeric Helps Your Brain Heal Itself: Spice Up Your Brain Power With Curry

Turmeric is the spice commonly found in curry - and, according to new research published in Stem Cell Research and Therapy, it may boost your brain proliferation or its power to repair itself. Aromatic-turmerone is a compound found within turmeric, and it's this compound researchers from the Institute of Neuroscience and Medicine in Julich, Germany, injected directly into the neutral stem cells located in a rat's brain.

http://ift.tt/1Bilpo2

Bring a Friend to Donate Blood

Canadian Blood Services is asking all eligible Canadians to donate blood this fall and to bring a friend to their next appointment. Higher than expected cancellations and no-shows over the past months have put extra pressure on the national blood supply.

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Paul, Cruz Duel at - Values Voter' EventBy Olivia Nuzzi

Rand Paul and Ted Cruz's back-to-back speeches at Friday's Values Voter Summit offered a preview of what the Republican presidential primary would look like should the two senators decide to run for president in 2016. The Family Research Council, a major social conservative group, hosts the Values Voter Summit in Washington, D.C. each year.

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Def Leppard's Vivian Campbell Details Lymphoma Treatment Plans in Message to Fans

Def Leppard guitarist Vivian Campbell sounds just as upbeat as ever about his chances of beating the Hodgkin's lymphoma he was diagnosed with in 2013 , but his latest round of treatment will keep him off the road for a series of upcoming live dates. Campbell, who briefly thought he'd wiped out the disease with a previous course of treatment, only to find that it had returned months later, appears to be back in remission , but has been advised to aggressively pursue any last vestiges with a stem cell transplant.

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UCLA stem cell research may lead to new cancer treatments

Significant research is ongoing at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research . The center's latest breakthrough was the discovery that a unique protein, pleiotrophin, can promote recovery of bone marrow-derived stem cells and the blood system after injury.

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BIOforward Announces Winners of 2014 Bioscience Vision Summit's Emerging Company Showcase

The showcase is part of the 2014 Bioscience Vision Summit, being held on -based early stage companies were chosen because they have transitioned successfully out of research and development, with good proof of concept for their products. Each was judged to have a unique value proposition.

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Promising drug candidate for Alzheimer's found in turmeric compound

The bright yellow spice sitting in your kitchen - that you sometimes use to make curry powder - has a compound that could be used as a drug candidate for treating neurological disorders. Researchers from the Institute of Neuroscience and Medicine in Julich, Germany, say a turmeric compound promotes stem cell proliferation and differentiation in the brain, giving hope for patients who suffer from stroke and Alzheimer's disease.

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Brain Repair "May Be Boosted By Curry Spice," Study

I2-Catenin and NF-IoB co-activation triggered by TLR3 stimulation...

Tel: +613 562 5624; Fax: +613 562 5452; E-mail: lwang@uottawa.ca Cancer stem cells are responsible for tumor initiation and progression. Toll-like receptors are highly expressed in cancer cells and associated with poor prognosis.

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With NIH Grant, Cedars-Sinai Helps Bring Big Data to Neuro Disease Research

Investigators at the Cedars-Sinai Board of Governors Regenerative Medicine Institute have received a grant from the National Institutes of Health to participate in a consortium taking the study of motor neuron disorders - such as Lou Gehrig's disease and spinal muscular atrophy - to a new, comprehensive perspective. "We will be working as part of an NIH initiative to create databases of disease 'signatures' by generating and analyzing thousands of data points.

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Def Leppard star taking break to battle cancer

FIGHTING CANCER: The "Pour Some Sugar On Me" hitmaker announced his Hodgkin's lymphoma was in remission in November, but had to backtrack when medics advised him the disease had returned at the beginning of 2014. Def Leppard guitarist Vivian Campbell is taking a break from touring to focus on beating cancer once and for all.

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Journey from stem cell to blood cell revealed

Researchers have discovered previously undetected steps in the process by which stem cells become blood cells, a process called haematopoiesis. An international collaboration, including Winthrop Professor Wendy Erber, has established that a highly complex series of events determine the fate of closely related populations of blood progenitor cells.

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Research paves path to accelerating, enhancing platelet production

... and differentiation in the brain, reveals new research published today in the open access journal Stem Cell Research & Therapy. The findings suggest aromat ... A triple-punch of antibodies both prevented hepatitis C infection and wiped out the ...

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Scientists advance understanding of autoimmunity with discovery of...

Autoimmune B cells cause the over-activation and death of NKT cells via presentation of altered lipids. Credit: A*STAR BTI Scientists from A*STAR's Bioprocessing Technology Institute have established a clearer relationship between two cells which serve our body's natural defence mechanisms against diseases and infections.

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Global Market for Tissue Engineering and Regeneration to Reach $56.9...

According to new report from BCC Research, the global market for tissue engineering and regeneration is expected to grow to nearly $56.9 billion, registering a compound annual growth rate of 22.3% from 2014 to 2019. BCC Research reveals in its new report, TISSUE ENGINEERING AND REGENERATION: TECHNOLOGIES AND GLOBAL MARKETS , the global market for tissue engineering and regeneration is expected to grow to nearly $56.9 billion, registering a compound annual growth rate of 22.3% from 2014 to 2019.

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With NIH grant, Cedars-Sinai helps bring big data to neuro disease research

Health Alert: "Talk" Therapy More Effective

Some promising news about a spice found in many kitchens -- turmeric. German researchers say a compound found in the spice promotes brain stem cell recovery and function in lab animals.

http://ift.tt/YipQlM

Catalogue of how white cells are formed by blood stem cells

For the first time, a comprehensive catalogue has been generated of transcription factors and other proteins that regulate the sophisticated processes leading to the formation of different types of blood cells, including the white ones by blood stem cells , the scientific paper Science reports. This study is one of three BLUEPRINT papers published in Science .

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Clarksburg man shows courage when faced with cancer

Rodolfo Padilla and his wife, Luisa, of Clarksburg following the Voices Against Brain Cancer inaugural Join the Voices! D.C. Walk on Sunday, Sept. 21, where he won the Courage Award.

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Dying brain cells cue new brain cells to grow in songbird

Using a songbird as a model, scientists have described a brain pathway that replaces cells that have been lost naturally and not because of injury. If scientists can further tap into the process, it might lead to ways to encourage replacement of cells in human brains that have lost neurons naturally because of aging or Alzheimer's disease.

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UCLA scientists unlock protein that can accelerate recovery in cancer ...

... Diseases and National Heart, Lung, and Blood Institute. Additional funding was provided by the UCLA Broad Stem Cell Research Center.

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Journey from stem cell to blood cell revealed

Persistence of Virus Reservoirs in ART-Treated SHIV-Infected Rhesus...

Despite many advances in AIDS research, a cure for HIV infection remains elusive. Here, we performed autologous hematopoietic stem cell transplantation in three Simian/Human Immunodeficiency Virus -infected, antiretroviral therapy -treated rhesus macaques using HSCs collected prior to infection and compared them to three SHIV-infected, ART-treated, untransplanted control animals to assess the effect of conditioning and autologous HSCT on viral persistence.

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HIV: radiation exposure before stem cell transplant 'may not have cured Berlin patient'

Timothy Ray Brown, also known as the "Berlin patient," is the only human believed to have been cured of HIV, following a bone marrow transplant from a donor immune to the virus. Now, researchers of a new study published in PLOS Pathogens have tested the potential mechanisms underlying this cure in monkeys.

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Humble turmeric may treat neurological disorders

The findings suggest that aromatic turmerone could be a future drug candidate for treating neurological disorders such as stroke and Alzheimer's disease. While several substances have been described to promote stem cell proliferation in the brain, fewer drugs additionally promote the differentiation of stem cells into neurons which constitutes a major goal in regenerative medicine.

http://ift.tt/1BfjujT

BRD4 protein appears to play key role in keeping stem cells in immature "pluripotent" state

A protein implicated in several cancers appears to play a pivotal role in keeping stem cells in an immature "pluripotent" state, according to a new study by NYU Langone Medical Center scientists. The study is published online today in Cell Reports .

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"Juventas Therapeutics, Inc. - Medical Equipment - Deals and...

The company develops regenerative therapies to treat life-threatening diseases. Its products include JVS-100 and JVS-200.

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Stem cell transplant does not cure SHIV/AIDS after irradiation of infected rhesus macaques

Secrets of cell regeneration studied

Steinberg: Urgent action needed

Amid the unrelenting furor surrounding the NFL and domestic violence the past three weeks, a critically important story concerning football, and all collision sports slipped by virtually unnoticed. A projection was made from NFL documents in the concussion lawsuit as to what the future holds for current players.

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Biomarkers, stem cells offer new ways to treat deadly gut disease in premature babies

... gut and possibly other organ systems dysregulated by NEC to function properly." The work, published in Stem Cell Research and Therapy , earned her the 2013 BioMed Central Research Award in Translational Medicine. It also provided the foundation for ...

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Thursday, September 25, 2014

Lab Head, iPSC Platform - " Neuroscience

The company's mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 25,000 people worldwide and markets medicines in more than 170 countries.

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Protecting the Body from Itself

... Some of the key research areas include immunology, expression engineering, animal cell technology, stem cell research, microbial fermentation, downstream purification and analytics. For more information about BTI, please visit ...

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Devon Still's daughter has tumor removed

In a season full of bad stories, one of the best has come in Cincinnati, where defensive lineman Devon Still 's four-year-old daughter has had a tumor completely removed. Via Coley Harvey of ESPN.com, Leah Still endured a six-hour procedure on Thursday , which resulted in the removal of all cancer.

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Volatile essential oil compound may hold key to reversing neurological disorders

... researchers are seeking to change that with new research published September 25, 2014 in the journal Stem Cell Research & Therapy , which suggests aromatic ( ar -) turmerone promotes stem cell proliferation and differentiation in the brain. Ar ...

http://ift.tt/1DAFc5S

Turmeric link to brain cell repair

COULD the common curry spice turmeric have an effect on brain cell repair? Researchers say an ingredient in it may hold the key. NEWS that taking paracetamol during pregnancy increases the risk of children having ADHD is "alarming", says an Auckland University researcher.

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Mechanics of tissue growth requires communication between cells

Engineers have combined mechanics with biology to make key discovery about communication between cells. When the body forms new tissues during the healing process, cells must be able to communicate with each other.

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Tumeric 'link' to brain cell repair

According the the research from Germany, an ingredient in the yellow curry spice turmeric may hold the key to repairing the brains of people with neurodegenerative diseases such as Alzheimer's. In laboratory tests, aromatic turmerone promoted the proliferation of brain stem cells and their development into neurons, effectively 'regenerating' brain tissue.

http://ift.tt/1qA7rHM

Curry spice 'helps brain self-heal'

Turmeric compound boosts regeneration of brain stem cells

A bioactive compound found in turmeric promotes stem cell proliferation and differentiation in the brain, reveals new research published today in the open access journal Stem Cell Research & Therapy . The findings suggest aromatic turmerone could be a future drug candidate for treating neurological disorders, such as stroke and Alzheimer's disease.

http://ift.tt/1BdzH9q

Epigenetics in acute promyelocytic leukaemia pathogenesis and...

Acute promyelocytic leukaemia driven by chimeric transcription factors encoding retinoic acid receptor alpha fusions is the paradigm of targeted cancer therapy, in which the application of all-trans retinoic acid treatments have markedly transformed this highly fatal cancer to a highly manageable disease. The extremely high complete remission rate resulted from targeted therapies using ATRA in combination with arsenic trioxide will likely be able to minimise or even totally eliminate the use of highly toxic chemotherapeutic agents in APL.

http://ift.tt/1rwKxGL

Vivian Campbell Taking A Break From Touring To Beat Cancer

Def Leppard guitarist Vivian Campbell is taking a break from touring to focus on beating cancer once and for all. The Pour Some Sugar On Me hitmaker announced his Hodgkin's lymphoma was in remission in November , but had to backtrack when medics advised him the disease had returned at the beginning of 2014.

http://ift.tt/1n4mrTw

$1.4 million NIH grant to UB scientist to study effects of arsenic on cancer tumor production

University at Buffalo faculty member Xuefeng Ren has received a $1.4 million grant from the National Institutes of Health to investigate the mechanisms of arsenic carcinogenesis - the process by which exposure to arsenic transforms normal cells into cancer cells. Chronic exposure to arsenic, a ubiquitous element widely distributed in the natural environment, affects up to 100 million people in 70 countries, including the U.S. It can lead to increased morbidity and mortality from both non-cancerous and cancerous effects, including diabetes, peripheral neuropathy, cardiovascular diseases and cancers of the bladder, lung, kidney and skin.

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Published Scientific Data Shows Plasticell??'s Massively Parallel...

New CombiCultA technology massively accelerates development of stem cell cures by enabling a single scientist to carry out 10,000 stem cell biology experiments in parallel 25 September 2014, Stevenage UK: UK stem cell biotech pioneer Plasticell Limited announced today the publication of scientific research which demonstrates how the company's innovative high throughput 'Combinatorial Cell Culturea ' technology allows a single scientist to carry out 10,000 stem cell biology experiments in parallel.

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Stem Cell Transplant Does Not Cure HIV/AIDS After Irradiation of Infected Primates

A study published on Sept. 25 in PLOS Pathogens reports a new primate model to test treatments that might cure HIV/AIDS and suggests answers to questions raised by the "Berlin patient," the only human thought to have been cured so far.

http://ift.tt/1qzDJTg

Muscling Up the Heart: A Preadolescent Cardiomyocyte Proliferation...

From the Department of Cardiology, Boston Children's Hospital, MA ; Departments of Pediatrics, Harvard Medical School, Boston, MA ; Harvard Stem Cell Institute, Cambridge, MA ; and Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA . Correspondence to Bernhard KA1 4hn, MD, Children's Hospital of Pittsburgh of UPMC, Division of Pediatric Cardiology, Richard King Mellon Institute for Pediatric Research, 4401 Penn Ave, Pittsburgh, PA 15224.

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Can you help Angela stay alive?

HEARTED BELIEF: Raymond Sunkel doesn't believe his wife Angela will die of leukaemia, but the odds are against her. You would fight if the chance was 50/50, if it was 80/20, if it was 90/10, if it was less.

http://ift.tt/1rgtObv

Stem cell study explains how mutation common in Asians affects heart health

Many Asians carry a mutation that causes their faces to flush when they drink alcohol. The affected gene is called ALDH2, and it also plays a role in cardiovascular health.

http://ift.tt/1vjwC6R

VistaGen Therapeutics, Inc. (VSTA) Sees AV-101 as Potential...

September 25, 2014 It's one of the single most sought-after drugs in the medical industry, and biotechnology company VistaGen Therapeutics may have it. What is so desperately needed is a drug able to treat a disease that afflicts tens of millions of people in the U.S., and hundreds of millions globally.

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Neuralstem Announces Presentation of Long-Term Follow Up Phase I Data in ALS Treatment Trial

Jonathan D. Glass, MD, site investigator at Emory University, recently presented long-term follow-up data regarding the Phase I trial testing of Neuralstem Inc's NSI-566 human neural stem cells in the treatment of amyotrophic lateral sclerosis . A Neuralstem news release notes that the presentation took place at the Annual Symposium on ALS of the Foundation Andre-Delambre, in Montreal, Canada, and was not open to the public.

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Genes causing pediatric glaucoma contribute to future stroke

Every year in Canada about 50,000 people suffer from a stroke, caused either by the interruption of blood flow or uncontrolled bleeding in the brain. While many environmental risk factors exist, including high blood pressure and smoking, stroke risk is also frequently inherited.

http://ift.tt/YcsB8b

A*STAR Release: Protecting The Body From Itself

Stem cell transplant does not cure SHIV/AIDS after irradiation of infected rhesus macaques

A study published on September 25th in PLOS Pathogens reports a new primate model to test treatments that might cure HIV/AIDS and suggests answers to questions raised by the "Berlin patient", the only human thought to have been cured so far. Being HIV-positive and having developed leukemia, the Berlin patient underwent irradiation followed by a bone-marrow transplant from a donor with a mutation that abolishes the function of the CCR5 gene.

http://ift.tt/1Bcf0us

Stem cell transplant does not cure SHIV/AIDS after irradiation of infected rhesus macaques

Carnival, blood drive raises childhood cancer awareness

This weekend, they will come together in hopes of shedding more light on one specific cause A A A - childhood cancer A - while remembering Drew Goodman, who died at the age of 12 from the disease. From left: Beaverdam Volunteer Fire Company members Joe Mallory, Jeff Males, Scott Mallory, Matt Middleton, Kenny Jones, Alcie Hall and Christopher Perry with Drew Goodman as he is named an honorary member.

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UCLA stem cell research may lead to new cancer treatments

Marked improvement in transplant success on the way, says Stanford immunologist

This is the third installment of our Biomed Bites series , a weekly feature that highlights some of Stanford's most compelling research and introduces readers to innovative scientists from a variety of disciplines. "Boost your immune system" is practically a mantra for some health-savvy folks who chug vitamin C or oregano oil to ward off errant germs.

http://ift.tt/YcvzcR

Celldex Therapeutics, Inc. Initiates Pilot Study Of CDX-301 In...

Celldex Therapeutics, Inc. today announced the initiation of a pilot study of CDX-301 for the mobilization and transplantation of allogeneic hematopoietic stem cells in patients with hematological malignancies undergoing hematopoietic stem cell transplantation . The study will explore the utility of CDX-301, also known as FMS-like tyrosine kinase-3 ligand or Flt3L, alone and in combination with MozobilA and is supported by preclinical data demonstrating that the combination of CDX-301 and Mozobil increased hematopoietic stem cell mobilization and improved transplantation of mobilized cells.

http://www.biospace.com/news_story.aspx?StoryID=347804&full=1

NYU Langone scientists identify key factor that maintains stem cell identity

Following inhibition of a key protein, these embryonic stem cells underwent differentiation and lost their pluripotency, the ability to become any cell type. . The new findings suggest that BRD4 enforces stem cell identity from an even higher regulatory level in the cell.

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Advanced Cell Technology Announces Final Patient Treated in...

The successful transplantation of the Company's proprietary RPE cells in the last patient of twelve represents the completion of the enrollment stage of this trial. The trial is a prospective, open-label study designed to determine the safety and tolerability of the Company's RPE cell therapy following sub-retinal transplantation into patients.

http://www.hispanicbusiness.com/2014/9/25/advanced_cell_technology_announces_final_patient.htm

Journal retracts bipolar study with 'fabricated' data

... gibberish. In the same month, a South Korean scientist had a suspended jail term upheld for having faked stem cell research findings 10 years earlier that raised hopes of treatments for diseases like cancer and diabetes. Hwang Woo-suk had claimed in ...

http://ift.tt/1v3p1tV

Sally Bee Health Food Cook and Author Dashes from Her Interview with...

After another morning's TV work Celebrity Cook and survivor of 3 heart attacks, Sally Bee, presented to primary school children and parents on the reasons why she stored the stem cells from within her children's teeth The Super Tooth Fairy delivering a tooth for stem cell harvesting. Just one of the BioKidz characters created by BioEden Once you learn about Sally's story of survival following 3 heart attacks in one week, you cannot fail to be moved, particularly as this happened to Sally at the age of 35. Once you meet Sally in person, you cannot fail to be impressed by this iconic woman, whose survival she puts down to a healthy lifestyle and the will not to leave her husband and 3 children, without a wife and mother.

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Politics: Campaign ready to move beyond stem cells - " almost

There are other issues in the race for S.C House District 108, and the candidates say they want to talk about them.

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Advanced Cell Technology Announces Final Patient Treated in...

Advanced Cell Technology, Inc. , a leader in the field of regenerative ophthalmology, announced today that it has completed treatment of the final patient in its U.K. based Phase 1 clinical trial for Stargardt's macular degeneration . The successful transplantation of the Company's proprietary RPE cells in the last patient of twelve represents the completion of the enrollment stage of this trial.

http://ift.tt/YaEqvy

Biomarkers, Stem Cells Offer New Ways to Treat Deadly Gut Disease in Premature Babies

Osiris Therapeutics to Present at the 2014 Stem Cell Meeting on the Mesa

Osiris Therapeutics, Inc. , the leading cellular regenerative medicine company focused on developing and marketing products to treat conditions in wound care, orthopedics and sports medicine markets, announced today that Lode Debrabandere, Ph.D., President and Chief Executive Officer, is scheduled to present at the Stem Cell Meeting on the Mesa, on Tuesday, October 7, 2014 at 5:15 p.m. PST in La Jolla, CA.

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Celldex Therapeutics Initiates Pilot Study of CDX-301 in Allogeneic...

Celldex Therapeutics, Inc. today announced the initiation of a pilot study of CDX-301 for the mobilization and transplantation of allogeneic hematopoietic stem cells in patients with hematological malignancies undergoing hematopoietic stem cell transplantation . The study will explore the utility of CDX-301, also known as FMS-like tyrosine kinase-3 ligand or Flt3L, alone and in combination with Mozobil and is supported by preclinical data demonstrating that the combination of CDX-301 and Mozobil increased hematopoietic stem cell mobilization and improved transplantation of mobilized cells.

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Telomere-regulating Genes and the Telomere Interactome in Familial Cancers

Telomeres are repetitive sequence structures at the ends of linear chromosomes that consist of double-stranded DNA repeats followed by a short single-stranded DNA protrusion. Telomeres need to be replicated each cell cycle and protected from DNA-processing enzymes, tasks that cells execute using specialized protein complexes such as telomerase , which aids in telomere maintenance and replication, and the shelterin complex, which protects chromosome ends.

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Here are our first-ever Health Care Innovators honorees

These winners created new health care products and strategies that have made health care more accessible, efficient and effective. They will be featured in the Nov. 7 issue of the Baltimore Business Journal and will be recognized at a breakfast at the Hotel at Arundel Preserve on Nov. 7. Farzad Mostashari, the former national coordinator for health IT for the federal health department, will be the keynote speaker at the event.

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Novel role of Engrailed 1 as a prosurvival transcription factor in...

Correspondence: Professor P Blancafort, Cancer Epigenetics Group, School of Anatomy, Physiology and Human Biology, The University of Western Australia, 35, Stirling Highway, Crawley, WA 6009, Australia. E-mail: pilar.blancafort@uwa.edu.au Basal-like breast tumors are aggressive cancers associated with high proliferation and metastasis.

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Investigating human disease using stem cell models

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Tractable and accurate disease models are essential for understanding disease pathogenesis and for developing new therapeutics.

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Official White House Photo by Pete Souza

In 2008, Sens. Obama and Clinton fell over each other with promises to "follow the science." They were speaking particularly in criticism of President Bush's ban on stem-cell research and Republican resistance to the widespread findings regarding anthropogenic climate change.

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Prevention is better than cure with bowed tendons, say horse owners

Stem-cell therapy has been lauded as the way forward in the repair of tendon damage, but it transpires horse owners would rather prevent the potentially career-ending injuries in the first place than shell out for costly treatments. "What researchers are focusing on is not necessarily what people want," admits Professor Janet Patterson-Kane, professor of veterinary pathology at the University of Glasgow in Scotland.

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Nobel-Prize-winning - iPSC' Stem Cell Method Vastly Improved

Normally, it takes researchers many weeks to get the slightest .01 to 10 percent yield when making pluripotent stem cells from ordinary cells via the Nobel-Prize-winning induced pluripotent stem cell approach. But by adding just three compounds to the above recipe- including a shot of vitamin C- a New York group reports in Stem Cell Reports a huge 90 to 100 percent stem cell haul in under a week.

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Scientists Identify Key Factor That Maintains Stem Cell Identity

New mobile solar unit is designed to save lives when the power goes out

... uninterrupted electricity. Dr. Ellison, Director of Education and Ethics at Stony Brook University's Stem Cell Research Facility and Associate Director of the Center for Community Engagement and Leadership Development, is allowing scientists to ...

http://ift.tt/1rcgDZ6

Researchers from Korea Advanced Institute of Science and Technology...

Editor at Stem Cell Week -- Current study results on Stem Cell Research have been published. According to news reporting from , by NewsRx journalists, research stated, "Various biophysical and biochemical factors are important for determining the fate of neural stem cells .

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Wednesday, September 24, 2014

UCLA Scientists Unlock Protein that Can Accelerate Recovery in...

... Diseases and National Heart, Lung, and Blood Institute. Additional funding was provided by the UCLA Broad Stem Cell Research Center. About UCLA's Jonsson Comprehensive Cancer Center UCLA's Jonsson Comprehensive Cancer Center has more than 240 ...

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BrainStorm Receives Approval for Uplisting to the NASDAQ Capital Market

NEW YORK, NY & PETACH TIKVAH, ISRAEL / ACCESSWIRE / September 24, 2014 / BrainStorm Cell Therapeutics Inc. , a leading developer of adult stem cell technologies for neurodegenerative diseases, today announced that its shares of common stock have been approved for uplisting to the NASDAQ Capital Market, and hopes to commence trading on the NASDAQ Capital Market when trading begins on September 30, 2014. BrainStorm Cell Therapeutics Inc. is a biotechnology company engaged in the development of first-of-its-kind adult stem cell therapies derived from autologous bone marrow cells for the treatment of neurodegenerative diseases.

http://ift.tt/1CjQHwX

BioCrea Announces Upcoming Presentations At Leading International Conferences

"On target with rapid acting antidepressants" Radebeul, Germany, September 24, 2014 - BioCrea GmbH , the first-in-class CNS drug discovery specialist, today announced that Chief Executive Officer, Dr. Tom Kronbach, will present at the following three international life sciences conferences over the coming months.

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BrainStorm Receives Approval for Uplisting to the NASDAQ Capital Market

Cell Therapeutics Inc. is a biotechnology company engaged in the development of first-of-its-kind adult stem cell therapies derived from autologous bone marrow cells for the treatment of neurodegenerative diseases. The Company holds the rights to develop and commercialize its NurOwna technology through an exclusive, worldwide licensing agreement with Ramot, the technology transfer company of Tel Aviv University.

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BrainStorm Receives Approval for Uplisting to the NASDAQ Capital Market

The Company holds the rights to develop and commercialize its NurOwn technology through an exclusive, worldwide licensing agreement with Ramot, the technology transfer company of . NurOwn has been administered to over 30 patients with amyotrophic lateral sclerosis in clinical trials conducted in Statements in this announcement other than historical data and information constitute "forward-looking statements" and involve risks and uncertainties that could cause actual results to differ materially from those stated or implied by such forward-looking statements.

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Sisters' love will help Light the Night in Oakville

Diane Pike and Janine Fischer have always been close sisters. But after Fischer saved Pike's life earlier this year, the pair became inseparable.

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[Research Articles] Characterization of the molecular mechanisms...

Nearly 8% of the human population carries an inactivating point mutation in the gene that encodes the cardioprotective enzyme aldehyde dehydrogenase 2 . This genetic polymorphism is linked to more severe outcomes from ischemic heart damage and an increased risk of coronary artery disease , but the underlying molecular bases are unknown.

http://ift.tt/1rb5qrQ

Q Therapeutics, Inc. Expands Board Of Directors With Appointment Of As Independent Member

Q Therapeutics, Inc. , an emerging biotechnology company developing innovative cell therapy products for the treatment of debilitating diseases of the central nervous system, today announced the appointment of Hunter Jackson, Ph.D. as an independent member to the Company's Board of Directors. In addition, Dr. Jackson has agreed to serve on the Board's newly formed Governance and Nominating Committee; he will be joined on the Committee by current independent directors, Peter Grebow, Ph.D. and Peter Barton Hutt, Esq.

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Bioheart, Inc. Announces Successful Grand Opening Of Facility In South Africa

Bioheart, Inc. , a biotechnology company focused on the discovery, development and, subject to United States regulatory approval, commercialization of autologous cell therapies for the treatment of degenerative diseases, announces a successful grand opening of the laboratory and clinic in South Africa. The new facility, named South African Stem Cell Institute , immediately began treating patients.

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Scientists use stem cells to learn how common mutation in Asians affects heart health

Human induced pluripotent stem cell-derived cardiomyocytes from carriers of the genetic polymorphism 2*2 in the cardioprotective enzyme Aldehyde Dehydrogenase 2 are more susceptible to ischemic damage. The cardiac myofilament protein Troponin T is still expressed; however, iPSC-CMs show a significant increase of TUNEL-positive nuclei relative to total nuclei labeled with DAPI .

http://ift.tt/1v01Lgr

Media Alert: Actors, Filmmakers, Athletes, Economists and Celebrities ...

The Blue Horizon Charitable Foundation team and its host committee invite their supporters, friends and those looking to support a worthy cause for an evening of fine foods, cocktails, entertainment and an opportunity to contribute toward Blue Horizon Charitable Foundation. Guests from around the world will be in attendance, including diplomats, consuls, economists, doctors, philanthropists, athletes and film/TV celebrities.

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Possible New Treatment for Soft Tissue Bone Formation in Burn Victims ...

... professor and Chair, Norman M. Rich Department of Surgery at USU; and Dr. Jeffrey M. Gimble, Center for Stem Cell Research and Regenerative Medicine, Tulane University School of Medicine, suggest that findings by a team of scientists led by Dr. ...

http://ift.tt/1ran8vn

'Tissue chip' to screen neurological toxins, researchers report

A faster, more affordable way to screen for neural toxins is under development, helping flag chemicals that may harm human development. Researchers will collaborate to refine existing 3-D human tissue chips and combine them into an integrated system that can mimic the complex functions of the human body.

http://ift.tt/1rainSB

Agilent Technologies Thought Leader Award Supports Cancer Stem Cell Research at Mount Sinai

... and clinical outcomes.' 'We are very pleased to support Dr. Cordon-Cardo's pioneering work in cancer stem cell research at one of the largest departments of pathology in the United States,' said technologies and solutions, could result in the ...

http://ift.tt/1uonD6m

$1 million Palo Alto Longevity 'Fountain of Youth' Prize -...

The Palo Alto Longevity Prize is a $1 million life science competition that challenges teams from all over the world to extend life spans. For more information log on to http://ift.tt/1sY5y9H .

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TAP Biosystems Release: New Webinars Explore Feed Strategy Challenges Using Mini Bioreactors

Nanogel Delivers Cellular Patches To Damaged Hearts

Transplanted cardiomyocytes derived from embryonic stem cells integrated better with mouse heart tissue when injected in a nanogel that mimics the extracellular matrix than when delivered alone . These images were taken four weeks after treatment.

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Media Alert * Media Alert * Media Alert * Media Alert

Actors, Filmmakers, Athletes, Economists and Celebrities unite to raise awareness of Blue Horizon Charitable Foundation at the Third Annual Gala PRLog - Sep. 24, 2014 - NEW YORK -- Media Alert * Media Alert * Media Alert * Media Alert Actors, Filmmakers, Athletes, Economists and Celebrities unite to raise awareness of Blue Horizon Charitable Foundation at the Third Annual Gala Who : Chairman, Orthopedic Trauma Surgeon Dr. Brian Mehling, CEO John Ferguson, COO Doreen Santora, President Eddie Amarante, singer and songwriter Nadia Lanfranconi, model, actress, former Miss USA and reality televison star of "Hollywood Exes " Shanna Moakler are among some of the guests who are attending this year's Blue Horizon Foundation Gala.

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Wednesday on Lake Effect: Stem Cell Research, Walker's Point Restaurants, Milwaukee Maker Faire

We'll learn about major work going on in the area of stem cell research. A Milwaukee scientist is the recipient of a major federal grant to study ways of reprogramming adult skin cells for use in treating liver disease.

http://ift.tt/1ChNEpg

Cell Isolation/Cell Separation Market Worth $5.1 Billion by 2019

... this region can be attributed to various factors including increasing government support for cancer and stem cell research and expanding biotechnology and biopharmaceutical industries in this region. Prominent players in the Cell Isolation Marke t ...

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Effects of Arsenic on Cancer Tumor Production

Agilent Technologies Thought Leader Award Supports Cancer Stem Cell Research at Mount Sinai

... and clinical outcomes." "We are very pleased to support Dr. Cordon-Cardo's pioneering work in cancer stem cell research at one of the largest departments of pathology in the United States," said Jacob Thaysen, vice president and general manager of ...

http://ift.tt/1spZMmU

New intervention in the fight against bowel cancer

... a substantial demand for novel approaches to inhibit the Wnt pathway. New research at the European Cancer Stem Cell Research Institute is asking the question of whether there are any other changes within the Wnt pathway that could prevent cancer ...

http://ift.tt/1B6JNZv

Study Determines MiMedx Allograft Effectively Recruits Circulating Stem And Progenitor Cells

The electronic publication of the peer-reviewed article is now available in the Journal of Surgical Research at 00803-8/abstract . The paper was authored by Chronic non-healing wounds are a growing healthcare burden associated with significant patient morbidity.

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New Mobile Solar Unit is Designed to Save Lives When the Power Goes Out

STONY BROOK, N.Y., September 24, 2014 - Brooke Ellison draws her own power from will, but the ventilator that keeps her alive requires uninterrupted electricity. Dr. Ellison, Director of Education and Ethics at Stony Brook University's Stem Cell Research Facility and Associate Director of the Center for Community Engagement and Leadership Development, is allowing scientists to field-test, at her home, the Nextek Power Systems STAR, a mobile solar generator with battery storage.

http://ift.tt/Y2Lme2

Study Determines MiMedx Allograft Effectively Recruits Circulating Stem and Progenitor Cells

MiMedx Group, Inc. , an integrated developer, processor and marketer of patent protected regenerative biomaterials and bioimplants processed from human amniotic membrane, announced today the publication of its latest peer-reviewed scientific study, "Progenitor Cell Recruitment By Dehydrated Human Amnion Chorion Grafts Promotes Neovascularization in a Murine Model of Dermal Ischemia", was electronically published in the Journal of Surgical Research . The electronic publication of the peer-reviewed article is now available in the Journal of Surgical Research at 00803-8/abstract .

http://ift.tt/1xfGX74

ALDH1A1 overexpression is associated with the progression and prognosis in gastric cancer

Aldehyde dehydrogenase 1 family member A1 is a cancer stem cell marker, and its expression correlates with prognosis in a number of malignancies. The aim of this study is to determine the relationship of ALDH1A1 expression with clinicopathological parameters and prognosis in gastric cancer.

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TALEN-Mediated Generation and Genetic Correction of Disease-specific...

Generation and precise genetic correction of patient-derived hiPSCs has great potential in regenerative medicine. Such targeted genetic manipulations can now be achieved using gene-editing nucleases.

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Using Songbird Brains to Investigate Regenerative Neurogenesis

Dutch director George Sluizer dead at 82

Nearly two years after an Australian tourist died in a quad bike accident, the negligent operator has walked away without a conviction or having to pay a cent. A 17-year-old man has been arrested and charged over the attack on good samaritan Lucy Knight yesterday afternoon.

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Challenge This

... some of the discoveries that were made can be applied elsewhere. They are making enormous strides with stem cell research. That's why I think anything at all you donate to [research for] a disease that is as deadly as this one is good. As my son ...

http://ift.tt/1qtz9G0

Making blood count

Tanyanee Chaisom found out her son, Zen, had Thalassemia when he was two years old. He was running a high fever and had a haemoglobin electrophoresis test - a blood screening done to evaluate the different types of haemoglobin in the bloodstream.

http://ift.tt/Y11RqV

UW-Madison and Morgridge researchers are creating tissue chip technology to screen neural toxins

A multidisciplinary team at the University of Wisconsin-Madison and the Morgridge Institute for Research is creating a faster, more affordable way to screen for neural toxins, helping flag chemicals that may harm human development. The National Institutes of Health announced today that the UW-Madison and Morgridge team is among 11 universities receiving support to continue the promising work as part of the Tissue Chip for Drug Screening program.

http://ift.tt/1xcj14h

St. Francis principal does ice bucket challenge

... FOR ALS HAS BEEN PROHIBITED BY CATHOLIC DIOCESES ACROSS THE COUNTRY. THE ASSOCIATION IS THE LEADER IN STEM CELL RESEARCH, WHICH GOES AGAINST THE CHURCH'S RIGHT-TO-LIFE PRINCIPLE. BUT TODAY WE'RE GOING TO SEE A VERY WET NUN. HOW DID THAT HAPPEN? " ...

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St. Francis principal takes ALS Ice Bucket Challenge

... for ALS has been prohibited by Catholic dioceses across the country. The association is the leader in stem cell research, which goes against the church's right-to-life principle. "We can restrict the funds donated to the cause to only work with ...

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Dying brain cells cue new brain cells to grow in songbird

Tuesday, September 23, 2014

Big Chinese medical plan for Queenstown

A Chinese billionaire is in advanced negotiations to fund a multimillion-dollar stem cell treatment and research centre in Queenstown. Medical entrepreneur Xia Jie, whose company Health 100 owns the largest chain of health clinics in China, plans to open overseas facilities to cater for wealthy clients.

http://ift.tt/1xaJ5wN

Regenerative Medicine Market (Bone and Joint) (By Technology - By...

Moreover, it has included stem cell therapy, tissue engineering and biomaterial under the umbrella of regenerative medicine. Regenerative medicine has wide areas of application such as cardiovascular, neurology, orthopedic and musculoskeletal diseases and disorders.

http://ift.tt/1ujvmCQ

Q Therapeutics Expands Board of Directors With Appointment of Dr....

In addition, Dr. Jackson has agreed to serve on the Board's newly formed Governance and Nominating Committee; he will be joined on the Committee by current independent directors, Peter Grebow, Ph.D. and Peter Barton Hutt, Esq. Dr. Jackson brings to Q Therapeutics more than 30 years' experience in the life science industry.

http://ift.tt/1ujvjH5

Dying brain cells cue new brain cells to grow in songbird

Brain cells that multiply to help birds sing their best during breeding season are known to die back naturally later in the year. For the first time researchers have described the series of events that cues new neuron growth each spring, and it all appears to start with a signal from the expiring cells the previous fall that primes the brain to start producing stem cells.

http://ift.tt/1r5U8Fe

Dying brain cells cue new brain cells to grow in songbird

Developing 'tissue chip' to screen neurological toxins

Inside wells about a fifth the size of a dime, a team from the University of Wisconsin-Madison and the Morgridge Institute for Research grew neural tissues from a combination of cell types that represent the main components of a developing brain, including neural progenitor cells, blood vessel cells and brain-specific immune cells called glial cells. This image shows the entire structure formed in the well, with nuclei in blue, neurons in green and glial cells in red.

http://ift.tt/1r5Cod7

Q Therapeutics Expands Board of Directors With Appointment of Dr....

UW-Madison Team Developing 'Tissue Chip' to Screen Neurological Toxins

MADISON, Wis. - A multidisciplinary team at the University of Wisconsin-Madison and the Morgridge Institute for Research is creating a faster, more affordable way to screen for neural toxins, helping flag chemicals that may harm human development.

http://ift.tt/1uj5kiS

UW-Madison team developing 'tissue chip' to screen neurological toxins

Stem cell centre proposed for resort

A chinese billionaire is in advanced negotiations to fund a multimillion-dollar stem cell treatment and research centre in Queenstown. Medical entrepreneur Xia Jie, whose company Health 100 owns the largest chain of health clinics in China, plans to open overseas facilities to cater for wealthy clients.

http://ift.tt/XWvNom

UW-Madison lands federal grant for cell research

Today's Paper, also known as the e-Edition, is an online replica of the printed newspaper. You can view today's paper or previous issues.

http://ift.tt/1qqG4Qd

Pembrokeshire Doctor's gift of life to patient 5,000 miles away

A 25-year-old doctor from Pembrokeshire has given the chance of survival to a patient over 5,000 miles away. Blood stem cells donated by Charlie Ratcliffe have been flown to South America to be received by a man the same age who has a form of leukaemia.

http://ift.tt/1x8i3pI

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