Reasons for ibrutinib therapy discontinuation in patients with chronic lymphocytic leukemia

About 10 percent of patients with chronic lymphocytic leukemia discontinued therapy with the Bruton tyrosine kinase inhibitor drug ibrutinib because of disease progression during clinical trials, according to a study published online by JAMA Oncology . CLL is the most prevalent leukemia in adults and it is not considered curable without an allogeneic stem cell transplant.

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