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Tuesday, March 31, 2015

Manipulation of a VEGF-Notch signaling circuit drives formation of...

Human pluripotent stem cell -derived endothelial lineage cells constitutes a promising source for therapeutic revascularization, but progress in this arena has been hampered by a lack of clinically-scalable differentiation protocols and inefficient formation of a functional vessel network integrating with the host circulation upon transplantation.

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