How Pluripotent Stem Cells Are Grown Affects Their Genetic Stability

Human pluripotent stem cells, which include both human embryonic stem cells and adult stem cells like induced pluripotent stem cells , need large numbers for transplantation into patients but the process of translating their potential into effective, real-world treatments involves deciphering and resolving a host of daunting complexities, according to a new study. The authors say they have definitively shown that the culture conditions in which stem cells are grown and mass-produced can affect their genetic stability.

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