Stem Cell Roundup: March 2015

Tuesday, March 31, 2015

Press release distribution, EDGAR filing, XBRL, regulatory filings

Celprogen Introduces Stem Cell Derived Conditioned Media as an Active Ingredient for Regenerative Cosmetic Industry Tested and Validated in Cosmetic Products for a Decade )--Celprogen, a global leader in Stem cell Research and Therapeutics, introduces stem cell derived conditioned media as an active ingredient for regenerative cosmeti... )--Phillips 66 will host its annual meeting of shareholders on Wednesday, May 6 at 9 a.m. CDT at the Marriott Houston Westchase, 2900 Briarpark Drive, Houston, T... CORRECTING and REPLACING Sanchez Production Partners Acquires Eagle Ford Shale Assets from Sanchez Energy Corp.; Raises Preferred Equity and Refinances Credit Facility )--SPP acquires Eagle Ford assets from Sanchez Energy for $85 million, financed with a private placement of newly created Class A Preferred Units, common units, and borrowing... )--Acucela Inc. , a clinical-stage biotechnology ... (more)

http://ift.tt/19AXpFH

Celprogen Introduces Stem Cell Derived Conditioned Media as an Active ...

Celprogen Inc., a leader in the Stem Cell Research and Therapeutics industry for the development of stem cell technologies for regenerative medicine, today announced that they have adult stem cell derived conditioned media containing stem cells growth components for regenerative skin care products. This stem cell derived conditioned media has been utilized in skin care products for over a decade.

http://ift.tt/1IkG4MH

Press release distribution, EDGAR filing, XBRL, regulatory filings

... Cosmetic Industry Tested and Validated in Cosmetic Products for a Decade )--Celprogen, a global leader in Stem cell Research and Therapeutics, introduces stem cell derived conditioned media as an active ingredient for regenerative cosmeti... ...

http://ift.tt/1bOXbfl

Press release distribution, EDGAR filing, XBRL, regulatory filings

Technology for Medicine

... research on coatings for joint replacements and spinal cord injury repair methods involving stem cells. Stem cell research is a highly promising branch of regenerative medicine with a growing number of applications. Stem cells can divide many times ...

http://ift.tt/1NGxriW

Press release distribution, EDGAR filing, XBRL, regulatory filings

Guide to organoid growth

AMSBIO has launched, at the 'Frontiers in Stem Cells & Cancer' EMBL-EMBO Symposium**, a guide that illustrates a variety of organoids grown from different tissues by leading international research groups using BME 2 reduced growth factor extracellular matrix that is available from the company. Organoids are organ-like structures that can be formed by 3D cell culture and differentiation of stem cells or organ progenitors.

http://ift.tt/1C4q7oH

Press release distribution, EDGAR filing, XBRL, regulatory filings

AES intends to u... Celprogen Introduces Stem Cell Derived Conditioned Media as an Active Ingredient for Regenerative Cosmetic Industry Tested and Validated in Cosmetic Products for a Decade )--Celprogen, a global leader in Stem cell Research and Therapeutics, introduces stem cell derived conditioned media as an active ingredient for regenerative cosmeti... )--Phillips 66 will host its annual meeting of shareholders on Wednesday, May 6 at 9 a.m. CDT at the Marriott Houston Westchase, 2900 Briarpark Drive, Houston, T... CORRECTING and REPLACING Sanchez Production Partners Acquires Eagle Ford Shale Assets from Sanchez Energy Corp.; Raises Preferred Equity and Refinances Credit Facility )--SPP acquires Eagle Ford assets from Sanchez Energy for $85 million, financed with a private placement of newly created Class A Preferred Units, common units, and borrowing... )--Acucela Inc. , a ... (more)

http://ift.tt/1I24LAD

Press release distribution, EDGAR filing, XBRL, regulatory filings

New study: Stem cell field is infected with hype

... myriad dry holes and dead ends. They should be vigilant against gaudy promises. That's especially true in stem cell research, which is slathered with so much money that immoderate predictions of success are common. The best illustration of that ...

http://ift.tt/1EzAesJ

Cardio3 BioSciences Announces Intention to Conduct a Registered Public Offering in the United States

Cardio3 BioSciences , a leader in engineered cell therapies with clinical programs initially targeting indications in cardiovascular disease and oncology, today announced its intention to conduct a registered public offering in the United States. The timing, number of shares and price of the proposed offering have not yet been determined.

http://ift.tt/1CucClU

Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation.

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Tissues can be soft like fat, which bears little stress, or stiff like bone, which sustains high stress, but whether there is a systematic relationship between tissue mechanics and differentiation is unknown.

http://ift.tt/1F0c9Gp

Premature Aging of Stem Cell Telomeres Linked to Emphysema

Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the "caps" or ends of chromosomes. Now, researchers from Johns Hopkins say they have discovered what goes wrong and why.

http://ift.tt/1bOfAsH

Study: Cancer drug found to restore memory in mice holds promise as Alzheimer's treatment

A drug originally designed to target cancer has been found to restore memory and reverse cognitive problems in mice with Alzheimer's disease-like symptoms and could offer a path forward to a treatment for humans someday, a new study found. Yale University researchers found that the previously approved drug, saracatinib, targeted beta amyloid deposits and reduced their toxic effect on surrounding brain cells.

http://ift.tt/1IjIQ4K

Oxford Immunotec Announces Availability of the T-SPOT.CMV Test in the United States

OXFORD, U.K. and MARLBOROUGH, Mass., March 31, 2015 -- Oxford Immunotec Global PLC , a global, commercial-stage diagnostics company focused on developing and commercializing proprietary tests for the management of immune-regulated conditions, today announced the availability in the United States of a new test that measures the strength of a patient's cellular immune response to cytomegalovirus . This T-SPOT .

http://ift.tt/1GdxdNY

Ocata Therapeutics Successfully Completes Dosing In Phase 1/2 RPE Studies

Ocata Therapeutics, Inc. , a leader in the field of regenerative ophthalmology, today announced that the company has completed dosing of its Phase 1/2 studies for dry age-related macular degeneration and Stargardt's Macular Degeneration . A total of 38 patients have been safely dosed.

http://ift.tt/1NEMGsJ

Premature aging of stem cell telomeres, not inflammation, linked to emphysema

CryoPort, Inc. Has Been Engaged By Roslin Cells Ltd For Logistics Support Of s iPSC Service

It is also establishing the Central Facility for the European Bank for induced stem Cells as part of a 35 million program funded by the Innovative Medicines Initiative. This aims to be the primary resource in As an effective and reliable liquid nitrogen vapor phase logistics solution is critical to any cell based research program, Cryoport's cryogenic logistics services are well positioned to support this burgeoning research area that the life sciences industry believes is critical to addressing many diseases.

http://ift.tt/19FFNYK

Cord Blood America, Inc. Announces 2014 Full Year Financial Results

Over the past twelve months, the Company has increased revenues via a more diversified service offering, sold its equity stake in Bio increasing overall profitability, negotiated more favorable vendor relationship agreements and made strategic investments in technology. In addition, we reached a Settlement Agreement on the remaining debt obligation of the Company and began making payments earlier than required.

http://ift.tt/1Dn2Xj3

Trial Shows Stem Cells Provide Long-Term Relief from Dangerous Crohn??'s Side Effect, Reveals

Stem cells may provide Crohn's disease sufferers relief from a common, potentially dangerous side effect - fistulas - according to the results of a phase 2 clinical trial published in the latest issue of STEM CELLS Translational Medicine . After receiving an injection of their own adipose-derived stem cells , which are collected from fat tissue, the fistulas in 75 percent of the trial participants were completely healed within eight weeks of their last treatment and remained so two years later.

http://ift.tt/19FgK8c

UTSA biologist selected to receive Dist. Service Award from Society for the Study of Reproduction

... Institute, McCarrey's leadership has helped position the College of Sciences as an area of excellence in stem cell research. Additional stem cell researchers have been added to UTSA's faculty since McCarrey's hire, and more UTSA students are ...

http://ift.tt/1C2McUH

Knights Of Columbus Launches Catholic Faith-Based Mutual Funds

... that runs afoul of Catholic values. For example, that would include any business involved in embryonic stem cell research, abortion, contraceptives, human cloning or pornography, Minopoli said. The Knights of Columbus takes the doctrine from the ...

http://ift.tt/1IMYUN9

Capricor Therapeutics, Inc. Completes Enrollment Of Phase II Clinical ...

Capricor Therapeutics, Inc. , a biotechnology company focused on developing novel therapeutics for the treatment of cardiovascular diseases, today announced that it has completed enrollment of its first Phase II clinical trial of Cenderitide in ambulatory heart failure patients. Cenderitide is in development for the outpatient treatment of patients following an acute admission for heart failure, as well as other potential indications.

http://ift.tt/1Ex4che

Premature Aging of Stem Cell Telomeres, Not Inflammation, Linked to Emphysema

Stem Cells Provide Long-Term Relief from Dangerous Crohn's Side Effect

Durham, NC - Stem cells may provide Crohn's disease sufferers relief from a common, potentially dangerous side effect - fistulas - according to the results of a phase 2 clinical trial published in the latest issue of STEM CELLS Translational Medicine . After receiving an injection of their own adipose-derived stem cells , which are collected from fat tissue, the fistulas in 75 percent of the trial participants were completely healed within eight weeks of their last treatment and remained so two years later.

http://ift.tt/1IizSVm

ID4 Gene Switch Might Tame Triple Negative Breast Cancers

Triple-negative breast cancers are around 15% of all breast cancers and they lack any of the three receptors that would make them responsive to targeted drugs. Triple-negative breast cancer patients have a higher risk of disease recurrence and shorter survival than those with other breast cancers and tend to fall into two categories: those that succumb to their disease within 3-5 years, regardless of treatment; and those that remain disease free for longer than the average non-triple-negative breast cancer patient .

http://ift.tt/1GcmhzZ

Generous donor busts myths about stem cell donation

A POLICE officer who donated his stem cells to help others is urging more potential lifesavers to join the register. David Bowley, from Consett , twice donated stem cells to save the life of a patient in desperate need of a transplant.

http://ift.tt/1yw3Y2j

International Stem Cell Corporation Announces 2014 Fourth Quarter and Year-End Results

International Stem Cell Corporation , a California-based biotechnology company developing novel stem cell-based therapies and biomedical products, today provided a business update and announced fourth quarter and year-end financial results for the period ended December 31, 2014.

http://ift.tt/19wWkPc

Ocata Therapeutics Successfully Completes Dosing in Phase 1/2 RPE Studies

Trial Shows Stem Cells Provide Long-Term Relief from Dangerous Crohn's Side Effect

Stem cells may provide Crohn's disease sufferers relief from a common, potentially dangerous side effect - fistulas - according to the results of a phase 2 clinical trial published in the latest issue of STEM CELLS Translational Medicine. It strongly demonstrated MSCs derived from ASCs are a safe and useful therapeutic tool for the treatment of Crohn's fistula.

http://ift.tt/1NzaYCt

Structure-based discovery of NANOG variant with enhanced properties...

NANOG transcription factor plays a central role in maintaining pluripotency, cooperating with OCT4 , SOX2, and other pluripotency factors. Although the physiological roles of the NANOG protein have been extensively explored, biochemical and biophysical properties in relation to its structural analysis are poorly understood.

http://ift.tt/19EPcQw

Manipulation of a VEGF-Notch signaling circuit drives formation of...

Human pluripotent stem cell -derived endothelial lineage cells constitutes a promising source for therapeutic revascularization, but progress in this arena has been hampered by a lack of clinically-scalable differentiation protocols and inefficient formation of a functional vessel network integrating with the host circulation upon transplantation.

http://ift.tt/1ae39py

Vanderbilt researchers identify potential new anti-cancer drug target

Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks. The protein, WDR5, is a "docking station" for a family of transcription factors called MYC that is overexpressed in the majority of malignancies and which contributes to an estimated 100,000 cancer-related deaths each year in the United States.

http://ift.tt/1adTFuy

Resolving sorting mechanisms into exosomes

The complexity of mechanisms driving protein sorting into exosomes is only beginning to emerge. In a paper recently published in Cell Research , Roucourt et al .

http://ift.tt/1MsTVab

The switch that might tame the most aggressive of breast cancers

Australian researchers have found that so-called 'triple-negative breast cancers '1 are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad.

http://ift.tt/1Cs2rhJ

Stem cells may improve tendon healing, reduce retear risk in rotator cuff surgery

An injection of a patient's bone marrow stem cells during rotator cuff surgery significantly improved healing and tendon durability, according to a study presented today at the 2015 Annual Meeting of the American Academy of Orthopaedic Surgeons . Each year in the U.S., more than 2 million people have rotator cuff surgery to re-attach their shoulder tendon to the head of the humerus .

http://ift.tt/1NCmYVT

Sight Restoration Through Stem Cell Therapy - Subject of June Symposium of Experts

Regenerative Stem Cell Applications to Eye Diseases Will Be Addressed by World Experts at an Invitation Only Symposium on "Sight Restoration Through Stem Cell Therapy" this June in Santa Monica, CA The Ocular Research Symposia Foundation has the unique ability to convene experts in the key foundational issues of stem cell research and discuss strategies to move the most promising research forward toward clinical trials. This June 13th, a distinguished group of Ph.Ds, M.Ds and Professors from the top U.S and International Medical Schools will come together in Santa Monica, California, to share their latest research on the application of stem cell therapy in treatments and cures for blinding eye diseases.

http://ift.tt/1adumst

The Irvine Stem Cell Treatment Center Announces Adult Stem Cell...

The Irvine Stem Cell Treatment Center announces a series of free public seminars on the use of adult stem cells for various degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief.

http://ift.tt/1IhfeVG

Coalition Duchenne Launches Youtube Interview Series 'Making a...

'We need to focus on changing the course of the disease,' said Coalition Duchenne Founder and Executive Director Catherine Jayasuriya. Newport Beach based charity Coalition Duchenne has launched an interview series titled "Making a Difference in Duchenne" on its Youtube channel focused on individuals making a difference in Duchenne muscular dystrophy research, care, awareness, and education.

http://ift.tt/1OTvFfS

Monday, March 30, 2015

Stem cells reverse MS: Medicine's next big thing?

Multiple sclerosis is a scary and unpredictable disease. A patient's own immune system attacks the nervous system, but a team of researchers at the University of Utah found that human stem cells didn't just stop symptoms in animals, they reversed them.

http://ift.tt/1EWRe7b

Stem cell research and treatment facility to be established in St Kitts

By Andre Huie BASSETERRE, St Kitts -- Plans are in the works to establish a stem cell research and treatment center in St Kitts in the near future. The plans were make public at a press conference organized by the St Kitts biomedical Research Foundation following the Foundation's Strategy Conference on Reverse Aging Treatments in the presence of several international scientists and stem cell research experts.

http://ift.tt/1DmNCR9

Controversial fertility treatments focus on eggs' power plants

Derived from bacteria, mitochondria are our cells' energy-producing powerhouses. Now, a Massachusetts company is convinced that these microscopic cylinders are also key to conceiving a baby, and it has persuaded several groups of physicians outside the United States to test that controversial premise in women with fertility problems.

http://ift.tt/1BYAhXR

Fasting and less-toxic cancer drug may work as well as chemotherapy

Fasting in combination with chemotherapy has already been shown to kill cancer cells, but a pair of new studies in mice suggests that a less-toxic class of drugs combined with fasting may kill breast, colorectal and lung cancer cells equally well. If shown to work in humans, this combination could replace chemotherapy and make fasting a potent component of a long-term strategy to treat cancer, according to senior author Valter Longo of USC.

http://ift.tt/1G9j3x7

Fujifilm Holdings to Acquire Cellular Dynamics International, Inc.

FUJIFILM Holdings Corporation and Cellular Dynamics International, Inc. , a leading developer and manufacturer of fully functioning human cells in industrial quantities to precise specifications, today announced that the two companies have entered into a definitive agreement whereby Fujifilm will acquire CDI via an all-cash tender offer to be followed by a second step merger. Fujifilm aims to acquire all issued and outstanding shares of CDI's common stock for $ 16.5 per share or approximately $ 307 million .

http://ift.tt/1BYsdqf

Cardio3 BioSciences Successfully Completes Futility Analysis Of Lead...

Cardio3 BioSciences , a leader in engineered cell therapy treatments, today announced the successful completion of a futility analysis for C-CureA , its lead cell therapy for congestive heart failure, currently being evaluated in a Phase III clinical trial in Europe and Israel . The Data Safety and Monitoring Board , an independent committee comprised of international experts, reviewed unblinded safety and efficacy data from CHART-1 and determined that such data did not support discontinuation of the trial on the basis of safety or futility and recommended that it continue without changes to the protocol.

http://ift.tt/1bKlvPs

Stemology Website Debuts New Channel

Stemology rolled out a new channel on the brand's website that addresses eight major skin concerns including wrinkles, dark spots, sun damage, sagging skin, dark circles, enlarged pores, sensitive skin and dry skin. Each skin concern page outlines a specific skin issue and its cause, along with a multi-pronged solution showcasing suggested Stemology products.

http://ift.tt/1EswSrH

"Neuralstem, Inc. (CUR) - Financial and Strategic SWOT Analysis...

The company develops and markets medicines based on human neural stem cell technology and cell therapy. It provides cell therapy treatment for ALS, ischemic stroke, spinal cord injury, glioblastoma, multiple sclerosis, optic neuritis, Alzheimer's disease, traumatic brain injury, peripheral nerve injury, diabetic neuropathy, lysosomal disease, Parkinson's disease, Huntington's disease, and cerebral palsy.

http://ift.tt/19BGeDy

Type 1 Diabetes, Progress With Stem Cells And Other Cell-Based Therapies

Novo Nordisk focuses on delaying the onset of Type 1 diabetes while paying attention to advances in stem cell technologies. Remarkable progress has been made in the treatment of Type 1 diabetes, which formerly was invariably fatal in young adults.

http://ift.tt/1FaqFy6

Hanson McClain Filed False Reports With the Security and Exchange...

... icial intelligence system provides big data and analysis for clinical applications, drug development, and stem cell research.

http://ift.tt/1MpBOSt

Solasia Acquires Exclusive License And Distribution Rights From...

LUND, Sweden & TOKYO-- -- Camurus AB and Solasia Pharma K.K. jointly announced today that they have entered into a license and distribution agreement for episilA oral liquid, a unique and effective treatment for the pain of oral mucositis, a treatment-limiting side effect of some cancer therapies, as well as other oral lesions. As part of the agreement Solasia receives exclusive commercialization rights to episilA in Japan and China, where it has ongoing operations and is building a specialty pharmaceutical infrastructure in the area of oncology and cancer supportive care.

http://ift.tt/1EVTbAQ

Major Transhumanism Conference Features Both Rising and Seasoned Experts

... Designer Babies , now that the technology is just a few years away? What about Jeb Bush (who carries the stem cell research moratorium stigma of his older brother)? Presumably, conservatives like newly announced US Presidential candidate Ted Cruz ...

http://ift.tt/1Mp4b3c

Cardio3 BioSciences Successfully Completes Futility Analysis Of Lead Cardiac Cell Therapy, C-Cure

Decision supports continuation of Phase III trial evaluating treatment for congestive heart failure Mont-Saint-Guibert, Belgium - Cardio3 BioSciences , a leader in engineered cell therapy treatments, today announced the successful completion of a futility analysis for C-CureA , its lead cell therapy for congestive heart failure, currently being evaluated in a Phase III clinical trial in Europe and Israel . The Data Safety and Monitoring Board , an independent committee comprised of international experts, reviewed unblinded safety and efficacy data from CHART-1 and determined that such data did not support discontinuation of the trial on the basis of safety or futility and recommended that it continue without changes to the protocol.

http://ift.tt/1CDsKTz

Japan's FUJIFILM to Acquire U.S. Cellular Dynamics for $307M

March 30, 2015 By Alex Keown , BioSpace.com Breaking News Staff TOKYO - Cellular Dynamics International , a manufacturer of human cells used in drug discovery and screenings, will be acquired by FujiFilm Holdings Corporation for $307 million, Fuji announced this morning. News of the acquisition sent stock prices souring this morning, with shares up more than 100 percent.

http://ift.tt/1IJJs4z

Bill Gross Fast Facts

... the Fuqua School of Business. 2006 - Donates $10 million to the University of California at Irvine for stem cell research and to help build a new research lab. The lab opens in 2010 and is named in their honor, Sue and Bill Gross Stem Cell Research ...

http://ift.tt/1BEnNEW

China mulls rules for stem-cell research

According to a document published by the National Health and Family Planning Commission and China Food and Drug Administration, stem-cell clinical trials refer to transplantation of stem-cells for the purpose of disease prevention or research. The document proposes that all clinical records of stem-cell providers and subjects should be kept for at lease 30 years.

http://ift.tt/1BEnN8b

New way to sort cells without limitations of traditional methods

A team of Stanford University School of Medicine researchers has come up with a new way of analyzing individual cell types by applying advanced mathematical analysis to the cells' contents. The method is analogous to analyzing a smoothie to find what fruits went into making it, the researchers say.

http://ift.tt/1xPorVc

Two different fat graft techniques have similar effects on facial skin

March 30, 2015 - Two approaches to fat grafting--injection of fat cells versus fat-derived stem cells--have similar effects in reversing the cellular-level signs of aging skin, reports a study in the April issue of Plastic and Reconstructive Surgery , the official medical journal of the American Society of Plastic Surgeons . Since the facial rejuvenation results are the same, the simpler approach using fat cells plus the "stromal vascular fraction" has advantages over the more time-consuming stem cell fat technique.

http://ift.tt/1CDhgzg

Two Different Fat Graft Techniques Have Similar Effects on Facial Skin

Newswise - March 30, 2015 - Two approaches to fat grafting-injection of fat cells versus fat-derived stem cells-have similar effects in reversing the cellular-level signs of aging skin, reports a study in the April issue of Plastic and Reconstructive SurgeryA , the official medical journal of the American Society of Plastic Surgeons . Since the facial rejuvenation results are the same, the simpler approach using fat cells plus the "stromal vascular fraction" has advantages over the more time-consuming stem cell fat technique.

http://ift.tt/1CDjtuK

FUJIFILM To Acquire Cellular Dynamics

Research and Markets: Global Market for Stem Cell Research Products 2015

Stem cell kits, including cytokine panels, lineage depletion antibodies, starter kits, antibody arrays and panels, primer pair panels, toxicity kits, detection, identification, characterization, and isolation kits, imaging, transfection, induced pluripotent stem cell reprogramming kits, and differentiation and expansion kits. Stem cells are valued for their ability to self-renew and differentiate into a wide variety of different cell types.

http://ift.tt/19ozt8b

Stem Cell Grants for Spina Bifida and Diabetic Wound Treatments

The state stem cell agency, California Institute for Regenerative Medicine , awarded a pair of grants totaling more than $7 million to UC Davis School of Medicine researchers who are working to develop stem cell therapies for spina bifida and chronic diabetic wounds. The funding is part of what the agency considers "the most promising" research leading up to human clinical trials using stem cells to treat disease and injury.

http://ift.tt/1aaEcvl

Stem cell firm Cellular Dynamics being acquired by Japanese company for $307 million

The Madison stem cell company founded by University of Wisconsin-Madison stem cell research pioneer James Thomson is being acquired by Tokyo-based Fujifilm Holdings Corp. for $307 million. Cellular Dynamics International Inc. was established in 2004 and now produces a variety of induced pluripotent stem cells for a uses in research and therapeutics.

http://ift.tt/1DdnRBg

At a CAGR of 6.5% Global Transplant Diagnostics Market Expected To...

The global transplant diagnostics market is poised to grow at a CAGR of 6.5% during 2014-2019, and is expected to reach a value of The global transplant diagnostics market is poised to grow at a CAGR of 6.5% during 2014-2019, and is expected to reach a value of ~645.0 Million in 2019. Although the mature markets , Antigen , Product , Application , End User - Global Forecasts to 2019 available at .

http://ift.tt/19nMv5Q

Researchers effectively and safely overcome radiation resistance in...

Improved survival rates demonstrated in mouse models of aggressive human leukemia using leukemia cells taken directly from patients, according to new EBioMedicine study A team of researchers led by Fatih M. Uckun, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles and Professor at the University of Southern California Keck School of Medicine has determined that radiation resistance in leukemia can be overcome by using an engineered protein they recently designed and developed as a new precision medicine against leukemia. This study has been published in open access journal EBioMedicine .

http://ift.tt/19nExd0

Fujifilm Holdings to Acquire Cellular Dynamics International, Inc.

Stem cells make similar decisions to humans

Scientists at the University of Copenhagen have captured thousands of progenitor cells of the pancreas on video as they made decisions to divide and expand the organ or to specialize into the endocrine cells that regulate our blood sugar levels. The study reveals that stem cells behave as people in a society, making individual choices but with enough interactions to bring them to their end-goal.

http://ift.tt/1CBPF1x

Fujifilm Holdings to Acquire Cellular Dynamics International, Inc.

Fujifilm aims to acquire all issued and outstanding shares of CDI's common stock for as a consolidated subsidiary of Fujifilm. The announced transaction was unanimously approved by the Boards of Directors of both companies.

http://ift.tt/19mXmNB

Antibacterial Hand Soaps Formulated with Lonzagard BKC cGMP Help...

Allendale, N.J. - March 26, 2015 Lonzagard BKC cGMP Benzalkonium Chloride is a suitable alternative to Triclosan as it satisfies the strict FDA requirements as an active for consumer health care and food professionals hand soaps and sanitizers. The U.S. Centers for Disease Control and Prevention likens "handwashing to a 'do-it-yourself' method to reduce the spread of germs and reduce the spread of diarrheal and respiratory illnesses."

http://ift.tt/19z3T7q

Cellular Dynamics' Webinar Spotlights Diabetic...

... of cellular therapeutics. CDI was founded in 2004 by Dr. James Thomson, a pioneer in human pluripotent stem cell research at the University of Wisconsin-Madison. CDI's facilities are located in Madison, Wisconsin, with a second facility in Novato, ...

http://ift.tt/1EoKBj4

Arizona Pain Stem Cell Institute Now Offering Stem Cell Therapy to...

Arizona Pain Specialists are now offering stem cell therapy to help patients avoid hip and knee replacement. The outpatient treatments at Arizona Pain Stem Cell Institute have been exceptionally effective and are administered by Board Certified pain doctors at ten locations Valleywide.

http://ift.tt/1G7t0LI

Center of Regenerative Orthopedics in South Florida Now Offering Stem ...

The top stem cell therapy practice in South Florida, Center of Regenerative Orthopedics, is now offering procedures to help patients avoid the need for hip and knee replacement. The procedures are partially covered by insurance and are offered by a highly skilled, Board Certified Orthopedic doctor in an outpatient setting.

http://ift.tt/1Coq3ni

Cell Therapy Catapult Signs Multiple Collaboration Agreements

The Cell Therapy Catapult has announced four separate collaborations with multiple-partners to deliver health and wealth to the UK through support from Innovate UK, formerly the Technology Strategy Board. The agreement with Plasticell is a further investment in a therapeutic programme utilising CombiCultA , the high throughput stem cell technology designed to solve bottlenecks in regenerative medicine development.

http://ift.tt/1Coiayp

Cardio3 BioSciences Successfully Completes Futility Analysis of Lead Cardiac Cell Therapy, C-Cure

Cardio3 BioSciences , a leader in engineered cell therapy treatments, today announced the successful completion of a futility analysis for C-Cure , its lead cell therapy for congestive heart failure, currently being evaluated in a Phase III clinical trial in Europe and Israel . The Data Safety and Monitoring Board , an independent committee comprised of international experts, reviewed unblinded safety and efficacy data from CHART-1 and determined that such data did not support discontinuation of the trial on the basis of safety or futility and recommended that it continue without changes to the protocol.

http://ift.tt/1BCrsmX

Sunday, March 29, 2015

H.S. wrestler paralyzed after 2013 injury undergoes stem cell therapy

A Williamson County High School athlete was living the life of a typical teenager but his life changed suddenly during a wrestling match. It happened in Huntsville, Alabama , in December 2013.

http://ift.tt/1EnHzf6

China leading the way in medical tourism services within stem cell therapy and regenerative medicines

Stem cells are no different, with thousands of foreign patients visiting clinics in China to have treatments unavailable in other markets. In May 2009, the Ministry of Science and Technology and the Ministry of Health released new guidelines for clinics offering stem cell therapy.

http://ift.tt/1ESr0mm

Postdoc in Gene Therapy of Lysosomal Storage Diseases

A postdoctoral Research Fellow position is available in the Cancer and Blood Diseases Institute at Cincinnati Children's Hospital Medical Center. The Pan lab has an immediate opening for a Postdoctoral Fellow in the Molecular and Gene Therapy Program.

http://ift.tt/1xN5qmh

Brainstorm Cell Therapeutics Given "Buy" Rating at Maxim Group

's stock had its "buy" rating reissued by investment analysts at Maxim Group in a note issued to investors on Sunday. They currently have a $14.00 target price on the stock.

http://ift.tt/1a6Qy7N

The CD44+/CD24- phenotype is enriched in basal-like breast tumors

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Human breast tumors are heterogeneous and consist of phenotypically diverse cells.

http://ift.tt/1a6MMLH

Australian researchers find gene that drives aggressive form of triple-negative breast cancer

Australian researchers have found that so-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad.

http://ift.tt/19vkwkA

'Off-switch' for aggressive breast cancers discovered

Researchers from Garvan Institute of Medical Research have found that so-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types. This helps explain why survival prospects for women with the diagnosis tend to be either very good or very bad.

http://ift.tt/1NrCq6Y

Gene identified that drives aggressive form of breast cancer

A team of researchers have identified a gene that drives one of the most aggressive forms of breast cancer. They hope that by finding a way to block the gene they may be able to make the cancer less aggressive.

http://ift.tt/1BST0Ed

Generation of Functional Thymic Epithelium from Human Embryonic Stem...

Cell Stem Cell , Vol. 13, No. 2. , pp. 219-229, doi:10.1016/j.stem.2013.04.004 To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.

http://ift.tt/1EjrLK7

Saturday, March 28, 2015

Stop exporting our sick children, say top doctors

Lifesave: Professor Owen Smith oversaw the stem cell transplant operation that saved the life of David Daly. Photo: Ciara Wilkinson.

http://ift.tt/1D3y5UA

Genetic regulators in blood cells located

ISLAMABAD: In order to provide scientists a tool to determine how a healthy blood cell can turn cancerous, researchers have located the regions, which determine if a particular gene would be active or silent in a blood cell. These regions in the blood cells are known as enhancers and promoters.

http://ift.tt/1NpxePa

'The Stem Cell Show': Premiering on TalkRadio 790 KABC - Sundays @...

... on the App Store or Google Play. While millions of dollars are being spent by most States each year on stem cell research, and while the National Institute of Health (NIH) spends $1 Billion dollars per year on stem cell research (Estimates of ...

http://ift.tt/1OKDzbi

Stem-cell therapy for dogs draws support, detractors

Deltona resident Paul Jaynes talks about the miraculous recovery his 9-year-old golden Labrador 'Cookie' made after having stem-cell surgery to resolve her crippling arthritis symptoms. Deltona resident Paul Jaynes talks about the miraculous recovery his 9-year-old golden Labrador 'Cookie' made after having stem-cell surgery to resolve her crippling arthritis symptoms.

http://ift.tt/1D1ayDK

Structural imprints in vivo decode RNA regulatory mechanisms.

Visualizing the physical basis for molecular behaviour inside living cells is a great challenge for biology. RNAs are central to biological regulation, and the ability of RNA to adopt specific structures intimately controls every step of the gene expression program.

http://ift.tt/19aUSBU

it validated Bush's belief

Acting as if he had a banned ESCR, which of course he hadn't, "the scientists" and their camp followers in the media and on Capital Hill accused the president of withholding cures from the ill in order to impose his religious beliefs on a reluctant public. Little noted in all of the caterwauling, was that ESCR and human-cloning research have been funded bounteously - to the tune of nearly $2 billion.

http://ift.tt/1Bwzeyp

Could These Experimental Drugs Eclipse Harvoni's Historic Launch?

Relatively few drugs attain the esteemed blockbuster status of $1 billion in annual sales. For those that do, many of them take several years to reach that mark.

http://ift.tt/1CvCPlr

PC in Cornwall turns life-saver after rare stem cell match

A police constable from Cornwall has successfully donated blood stem cells to save a patient suffering a rare blood disorder. PC Ryan Berry from Bodmin travelled to London in January to donate the cells after being identified by the Anthony Nolan Trust as a full match for a seriously-ill patient.

http://ift.tt/1xmzlBi

Genetics of Longevity

The most persuasive argument for the genetic influence on lifespan is the different lifespan of species. The best explanation we have of this absolute and static lifespan is the concept of the Hayflick Limit-a genetic program that kills cells.

http://ift.tt/1D6gZH7

Researchers discover genetic origins of myelodysplastic syndrome using stem cells

Induced pluripotent stem cells - adult cells reprogrammed back to an embryonic stem cell-like state - may better model the genetic contributions to each patient's particular disease. In a process called cellular reprogramming, researchers at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with myelodysplastic syndrome and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer .

http://ift.tt/1Gz0nrl

Radiation resistance in leukemia can be overcome by using new precision medicine, say researchers

A team of researchers led by Fatih M. Uckun, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles and Professor at the University of Southern California Keck School of Medicine has determined that radiation resistance in leukemia can be overcome by using an engineered protein they recently designed and developed as a new precision medicine against leukemia. This study has been published in open access journal EBioMedicine .

http://ift.tt/1ID9czv

Friday, March 27, 2015

[Report] Life-threatening influenza and impaired interferon amplification in human IRF7 deficiency

Severe influenza disease strikes otherwise healthy children and remains unexplained. We report compound heterozygous null mutations in IRF7 , which encodes the transcription factor interferon regulatory factor 7, in an otherwise healthy child who suffered life-threatening influenza during primary infection.

http://ift.tt/1CWgNbR

Stanford Professor Receives $1M Stem Cell Grant for 'Bubble Boy' Disease

Matthew Porteus, PhD, associate professor of pediatrics at the School of Medicine, was awarded $1 million today from the California Institute for Regenerative Medicine to pursue a stem-cell-based gene therapy approach to correcting a form of severe combined immunodeficiency in humans. The award was part of the state stem cell agency's Preclincal Development Awards.

http://ift.tt/1xl26OF

Husband plans 300 mile walk to pay for wife's stem cell transplant

Aaron Szukhent is undertaking an almost 300 mile walk to raise $25,000 to pay for his wife Wendy's stem cell transplant. Szukhent, of Flushing, Mich., says the couple hopes the stem cell treatment will help Wendy overcome multiple sclerosis--a disease she's been fighting for 15 years.

http://ift.tt/1EJBvbI

OHSU and other Oregon hospitals overbilled Medicare by millions

Oregon hospitals overbilled Medicare $23 million in 2013, an increase of $8 million over the previous year, a new analysis has revealed. The state's overbilling does not place Oregon high on a list of the worst states with Medicare waste - it only ranks 39th out of the 50 states - but does contribute to mismanagement that drained $46 billion in lost funds from the Medicare Trust Fund in 2014, says the advocacy group Council for Medicare Integrity.

http://ift.tt/1McVhWe

Grants help level the playing field for young moms in science

Thanks to a generous benefactor, young mothers doing laboratory research at the Massachusetts General Hospital in Boston can receive major grants to keep them from falling behind while they raise their children. Since 1993, the Claflin Distinguished Scholar Awards at MGH have helped junior female faculty with young children keep pace with their male peers, who don't face the same challenges to research productivity that women do during their child-rearing years.

http://ift.tt/1FSuivu

AstraZeneca To Collaborate With The Harvard Stem Cell Institute In Diabetes

AstraZeneca recently announced that it has entered into a five-year research collaboration with the Harvard Stem Cell Institute to adapt a technique that creates human beta cells from stem cells for use in screens of AstraZeneca's compound library in the search for new treatments for diabetes. The collaboration also aims to better understand how the function of beta cells declines in diabetes and research findings will be made available to the broader scientific community through peer-reviewed publications.

http://ift.tt/1HSuCeg

Cord-Blood Research Sits Poised for Therapeutic Discovery

Indeed, the history of therapeutic research is full of instances where a promising technology is not fully realized until long after an initial discovery. Consider, for example, monoclonal antibodies: The initial discoveries, along with the seminal research by CA sar Milstein and Georges KA hler, occurred in the 1970s-more than 20 years before there began to be a significant number of monoclonal antibody therapies approved for human use.

http://ift.tt/1MbR6dn

Genetic origins of myelodysplastic syndrome discovered using stem cells

Induced pluripotent stem cells -- adult cells reprogrammed back to an embryonic stem cell-like state--may better model the genetic contributions to each patient's particular disease. In a process called cellular reprogramming, researchers have taken mature blood cells from patients with myelodysplastic syndrome and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer.

http://ift.tt/1CUbbig

Foundation is rallying for brave little boys with rare condition

A FOUNDATION that has been set up in aid of two children who have Hunter Syndrome have has already raised more than 1,000. Jaz Price and Gary Harlock, who are from Newtown but now live in Oswestry, have two children, Jensen and Riley, who both have the serious condition Hunter Syndrome.

http://ift.tt/19Z0pwh

Precision Medicine Shaping the Future of Cancer Research

Nearly 50 years after the "war on cancer" was declared in the United States, precision medicine presages an era of increased understanding of the molecular basis of cancer and of the ability to design treatments tailored to a patient's own genetic profile, a panel of experts said Tuesday at a briefing sponsored by Columbia University. The event, a media conversation on the future of cancer, was held to mark the upcoming PBS broadcast of "Ken Burns Presents Cancer: The Emperor of All Maladies," based on the Pulitzer Prize-winning book by Columbia oncologist Siddhartha Mukherjee, M.D., DPhil.

http://ift.tt/194fVFX

Switch that might tame most aggressive of breast cancers

So-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types, researchers have found. They have also found a gene that drives the aggressive disease, and hope to find a way to 'switch it off'.

http://ift.tt/1bBw8Eo

UC Davis scientists win $7M in California stem-cell research grants

California's stem cell agency awarded $25 million in grants Thursday to develop new treatments - and researchers at the UC Davis School of Medicine got more than $7 million. California's stem cell agency awarded $25 million in grants Thursday to develop new treatments - and researchers at the UC Davis School of Medicine got more than $7 million.

http://ift.tt/1Ni8s5q

Mesoblast Limited Key Patent Allowed In Japan For The Treatment Of...

Mesoblast Limited today announced that the Japanese Patent Office has allowed a key patent covering the use of the Company's proprietary adult Mesenchymal Precursor Cells for the formation and repair of blood vessels in ischemic tissues. Japanese patent 2006-503990, entitled 'Perivascular Mesenchymal Precursor Cell Induced Blood Vessel Formation', covers the use of these cells derived from bone marrow, adipose tissue and dental pulp.

http://ift.tt/1Mb9enC

MRI based on a sugar molecule can tell cancerous from noncancerous cells

... R01 EB015032 and R01 EB015031), the National Cancer Institute (grant number U54 CA151838), the Maryland Stem Cell Research Foundation (grant number MSCRFII-0042), and the Pearl and Yueh-Heng Yang Foundation. The above story is based on materials ...

http://ift.tt/1D69eRB

If the drugs don't work on the cancer, transform it

Rather than designing drugs to target hard-to-treat cancers, what if such cancers could be made susceptible to existing treatments? That is the intriguing possibility raised by the discovery of a genetic switch that may be able to turn the most troublesome breast cancer into one of the easiest to tackle. The finding could also apply to stubborn ovarian cancers.

http://ift.tt/1942Igl

UW research will target how toxins affect the human body

Humans are constantly exposed to toxins from chemical substances in the environment, but scientists are unaware of potential affects on human development. A $6 million grant from the United States Environmental Protection Agency will fund a Human Models for Analysis of Pathways Center at University of Wisconsin, to analyze how these chemical materials are affecting human physiology, according to a UW statement .

http://ift.tt/1IDbgr6

The switch that might tame the most aggressive of breast cancers

IMAGE: Id4+ stem cells are in red, luminal cells in green, and all cells are marked with blue nuclear dye. view more Australian researchers have found that so-called 'triple-negative breast cancers'1 are two distinct diseases that likely originate from different cell types.

http://ift.tt/1ICKz60

The switch that might tame the most aggressive of breast cancers

Id4+ stem cells are in red, luminal cells in green, and all cells are marked with blue nuclear dye. Credit: Garvan Institute of Medical Research Australian researchers have found that so-called 'triple-negative breast cancers' are two distinct diseases that likely originate from different cell types.

http://ift.tt/1OCffbQ

MRI Based on a Sugar Molecule Can Tell Cancerous from Noncancerous Cells

... R01 EB015032 and R01 EB015031), the National Cancer Institute (grant number U54 CA151838), the Maryland Stem Cell Research Foundation (grant number MSCRFII-0042), and the Pearl and Yueh-Heng Yang Foundation. Caption: Normal cells (left) have far ...

http://ift.tt/1bAQTA1

Why some HPV infections go away and others become cancer

For people infected with the human papilloma virus , the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed. A new study finds that the body's ability to defeat the virus may be largely due to unpredictable division patterns in HPV-infected stem cells , rather than the strength of the person's immune response.

http://ift.tt/1H3QSOS

Regen BioPharma, Inc. Expands Research Capacity With New Laboratory Facilities

Regen BioPharma Inc. announced today the acquisition of new laboratory facilities in La Jolla area of San Diego, California. The laboratory space being leased by Regen is located within the Human BioMolecular Research Institute and provides the Company with access to molecular and cellular biology facilities critical to the Company's cancer stem cell research.

http://ift.tt/1937jzp

Clontech Laboratories, Inc. Signs Agreement With Ludwig Cancer Research For Access To Smart-Seq2

Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced that it has entered into an exclusive agreement with Ludwig Cancer Research for rights to the Smart-seq2 method for single-cell RNA-seq , which was developed inRickard Sandberg's laboratory at Ludwig Stockholm. As a result of this agreement, Clontech will become the exclusive supplier of SMART-Seq2 technology.

http://ift.tt/1FYOwSx

Obs-Gyne Exhibition to Highlight Women's Health in the Region

The 7th Obs-Gyne Exhibition and Congress kicks off in Dubai on Sunday next week. The event will showcase 50 regional and international leading companies in the field of fertility, obstetrics, gynaecology, midwifery and women's health.

http://ift.tt/1M9nSf2

The ethics of talking about 'HIV cure'

Background In 2008, researchers reported that Timothy Brown , a man with HIV infection and leukemia, received a stem-cell transplant that removed HIV from his body as far as can be detected. In 2013, an infant born with HIV infection received anti-retroviral treatment shortly after birth, but was then lost to the health care system for the next six months.

http://ift.tt/1xjzsxA

'Mini-lungs' Aid The Study Of Cystic Fibrosis

Scientists at the University of Cambridge have successfully created 'mini-lungs' using stem cells derived from skin cells of patients with cystic fibrosis, and have shown that these can be used to test potential new drugs for this debilitating lung disease. The research is one of a number of studies that have used stem cells - the body's master cells - to grow 'organoids', 3D clusters of cells that mimic the behaviour and function of specific organs within the body.

http://ift.tt/1M8S7D2

Mesoblast Key Patent Allowed in Japan for the Treatment of Heart...

Stem Cells Reverse MS: Medicine's Next Big Thing?

Multiple sclerosis is a scary and unpredictable disease. A patient's own immune system attacks the nervous system, causing numbness, dizziness, and in some cases, paralysis.

http://ift.tt/1H2SNTU

Thursday, March 26, 2015

Mesenchymal stem cell secretes microparticles enriched in pre-microRNAs.

Intercellular exchange of protein and RNA-containing microparticles is an increasingly important mode of cell-cell communication. Here we investigate if mesenchymal stem cells known for secreting therapeutic paracrine factors also secrete RNA-containing microparticles.

http://ift.tt/1M7Y5UI

$7M for UCD med researchers working on stem cell therapies

The state stem cell agency, California Institute for Regenerative Medicine, today awarded a pair of grants totaling more than $7 million to UC Davis School of Medicine researchers who are working to develop stem cell therapies for spina bifida and chronic diabetic wounds. The funding is part of what the agency considers "the most promising" research leading up to human clinical trials using stem cells to treat disease and injury.

http://ift.tt/1xjbh21

Bill Gross Fast Facts

CIRM Awards More than $25 Million To Develop New Treatments for Disabling Disorders

... However the CIRM science team recommended it for funding saying it addresses a significant bottleneck in stem cell research. The vote means that Carla Koehler at UCLA will now get $1.34 million for that research.

http://ift.tt/1D3fjOP

'Bubble boy' disease targeted by stem cell award to Stanford

... Institute for Regenerative Medicine , totaling $25.2 million. The funding from from California's stem cell research funding agency is designed to move not-quite-ready-for-prime-time experimental therapies closer to human clinical trials. Those ...

http://ift.tt/1yfeB9J

Fate Therapeutics, Inc. (FATE) on Course to Address Hematologic Malignancies with PROHEMA

March 26, 2015 It's nearly impossible to list all the ways in which stem cell exploration is important because the usefulness of these cells is virtually limitless. Stem cells have the potential to treat a huge range of diseases and conditions that millions of people around the world suffer from.

http://ift.tt/1HPWH2r

Experts set strategic priorities for lymphoma research

A committee of lymphoma experts today unveiled a strategic roadmap identifying key priority areas in both infrastructure and research that will be critical for advancing treatments for people with lymphoma. The report is meant to inform future research directions as well as funding decisions by strategic partners that could include government agencies and the private sector.

http://ift.tt/1GuqXSl

UCI team gets $5 million to create stem cell treatment for Huntington's disease

Leslie Thompson of the Sue & Bill Gross Stem Cell Research Center at UC Irvine has been awarded $5 million by the California Institute for Regenerative Medicine to continue her CIRM-funded effort to develop stem cell treatments for Huntington's disease. The grant supports her next step: identifying and testing stem cell-based treatments for HD, an inherited, incurable and fatal neurodegenerative disorder.

http://ift.tt/1OBdCuJ

For Greene Construction, Family and Business Share Unbreakable Ties

For nearly six months, Bob Greene spent every night sleeping in a fold-out chair in Boston Children's Hospital. His son was sequestered in a bubble-like isolation room in the bone marrow transplant unit.

http://ift.tt/19Ve1ZA

Vical Incorporated Expands Infectious Disease Portfolio With Novel...

Vical Incorporated today announced that it has expanded its infectious disease portfolio with the addition of a novel antifungal, ASP2397, in-licensed from Astellas Pharma Inc. . ASP2397 represents a potential new class of antifungal compounds to address invasive Aspergillus infections, which are major causes of morbidity and mortality in immunocompromised patients, including transplant recipients.

http://ift.tt/1GuLMgk

AstraZeneca teams with Harvard to make human beta cells for drug screening

Sourcing human beta cells may soon no longer be a challenge for AstraZeneca diabetes researchers thanks to a new partnership with stem cell scientists at Harvard University. The Anglo-Swedish drugmaker announced its partnership with the Harvard Stem Cell Institute today, explaining the collaboration will focus on converting stem cells into human beta cells for use in its diabetes drug candidate screening programme.

http://ift.tt/19V0nWk?

Chromothriptic Cure of WHIM Syndrome

Chromothripsis is a catastrophic cellular event recently described in cancer in which chromosomes undergo massive deletion and rearrangement. Here, we report a case in which chromothripsis spontaneously cured a patient with WHIM syndrome, an autosomal dominant combined immunodeficiency disease caused by gain-of-function mutation of the chemokine receptor CXCR4.

http://ift.tt/1NdRRj2

Human embryo modifications must be halted, scientists urge

... in the journal Nature and the journal Science by Nobel laureates and from the International Society for Stem Cell Research called for a pause on genome editing experiments on human embryos. It's the risks associated with modifying human sperm and ...

http://ift.tt/1BtxVRQ

'Hats for Logan' raises funds for Dexter student fighting cancer

Normally, wearing a cap inside Dexter Regional High School will earn you a reprimand from a teacher or an unplanned trip to the principal's office. Everyone was encouraged to wear some kind of headgear in honor of senior Logan Bagley of Harmony, who is waging a brave battle against Hodgkin's lymphoma.

http://ift.tt/1ydBo5M

First-in-Human Results for New Handheld Autofluorescence Imaging...

We previously reported on PRODIGI, a handheld autofluorescence imaging platform for real-time detection and tracking of bacterial infections in wounds. Canadian molecular imaging scientist Dr. Ralph DaCosta and colleagues at the Princess Margaret Cancer Center, University Health Network , have now published first-in-human results describing the use of PRODIGI for point-of-care real-time sampling and treatment guidance of bioburden in chronic wounds.

http://ift.tt/1HNYGV2

Researcher overcomes radiation resistance in leukemia with an engineered precision medicine

Improved survival rates demonstrated in mouse models of aggressive human leukemia using leukemia cells taken directly from patients, according to new EBioMedicine study IMAGE: CD19L-sTRAIL selectively binds to the CD19 receptor on leukemia cells via its CD19L moiety upon which its sTRAIL component kills the cells by engaging the TRAIL death receptors.

http://ift.tt/1NcXhLd

Why some HPV infections go away and others become cancer

The body's ability to clear an infection by the cancer-causing human papilloma virus may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response as previously thought. For people infected with the human papilloma virus , the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed.

http://ift.tt/19Ur79f

Researchers effectively, safely overcome radiation resistance in...

Improved survival rates have been demonstrated in mouse models of aggressive human leukemia using leukemia cells taken directly from patients, according to a new study. A team of researchers led by Fatih M. Uckun, MD, PhD, of The Saban Research Institute of Children's Hospital Los Angeles and Professor at the University of Southern California Keck School of Medicine has determined that radiation resistance in leukemia can be overcome by using an engineered protein they recently designed and developed as a new precision medicine against leukemia.

http://ift.tt/1Nd5kI5

On stem cell therapy, benefits

THERE is a lot of hype going on in some circles about stem cell therapy: Is it a cure-all? Is it the elusive fountain of youth? Wikipedia defines stem cell therapy as the "use of stem cells to treat or prevent a disease or condition." The process involves "the administration of live whole cells or maturation of a specific cell population in a patient for the treatment of the disease" as has been done in bone marrow transplants.

http://ift.tt/1NcZ42R

Cardio3 reports losing $18 million in 2014

... percent of Cardio3, as of March 3. Mayo Clinic first acquired equity in Cardio3 in 2007, when it licensed stem cell research by Mayo Clinic's Dr. Andre Terzic and Dr. Atta Behfar. Its cardiopoiesis technology repairs patients' hearts by ...

http://ift.tt/1FLF4U2

Sungduan: Growth factors

EVEN without surgery, one can now experience a dramatic improvement and even cure on health concerns such as diabetes, cancer, HIV, and cardiovascular diseases. This is through the stem cell technology and telomere science.

http://ift.tt/1NcNc0M

Researchers overcome leukemia radiation resistance with an engineered precision medicine

Blood test uses human stem cells to predict severe drug reactions

Scientists have developed a blood test using human stem cells that predicts whether new drugs will cause severe side effects. The test, which only requires blood from a single donor, could help prevent catastrophic inflammatory reactions known as a cytokine storm in people participating in drug trials.

http://ift.tt/1GYf45d

Combining the old and new to kill cancer cells

A team of Singapore based scientists have found that pairing a new approach with an old drug may be an effective approach to treat common cancers . In a landmark study, Professor David Virshup and Dr. Jit Kong Cheong, from Duke-NUS Graduate Medical School Singapore , identified a new signalling pathway that regulates the internal diet of cancers.

http://ift.tt/1GYoGNo

TSRI team discovers enzyme that keeps blood stem cells functional to prevent anemia

Stem cells can generate any type of cell in the body, but they are inactive most of the time--and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations.

http://ift.tt/1EWSZnt

Face for the cure

Timothy Ray Brown, the first man ever known to have been cured of HIV, with his dog, Jack, on Treasure Island in San Francisco. The media dubbed him "The Berlin Patient" after he became the first person cured of HIV after a grueling stem-cell transplant to treat his leukemia.

http://ift.tt/1EWSWrS

Bronx Boy To Lead Go The Distance Walk For Maria Fareri Children's Hospital

Gabriel Sanchez, 13, has been named grand marshal of the 11th Annual Go the Distance Walk and Family Fun Day for Maria Fareri Children's Hospital at Westchester Medical Center. Sanchez's official appointment as grand marshal appointment will be held Monday at 1 p.m. at St. Raymond Elementary School in the Bronx.

http://ift.tt/1M2MExn

Wednesday, March 25, 2015

Significant blocking of opioid tolerance with mesenchymal stem cell transplant

Mesenchymal stem cell transplantation reduced opioid tolerance and opioid-induced hyperalgesia caused by daily morphine injections in rats, according to new research. Not only was opioid tolerance prevented when the rats were transplanted with MSC before repeated morphine injections, but tolerance was reversed when the rats were treated after opioid tolerance had developed, results demonstrated.

http://ift.tt/1EVPmyb

'Roll-up a Sleeve for Bella' at New Kensington blood drive

Nine-year old Isabella "Bella" Carabin-Lindgren is the beneficiary of the Penn State New Kensington's semiannual community Blood Drive from 9 a.m. to 3 p.m., Wednesday, April 1, in the campus Art Gallery in Upper Burrell. Bella, a fourth-grader at Mary Queen of Apostles School in the nearby city of New Kensington, was diagnosed with Ewing's Sarcoma when she was 10-months old.

http://ift.tt/19RLp3d

NAPSR News: AstraZeneca and Harvard team up for diabetes research

PRLog - March 25, 2015 - WASHINGTON -- AstraZeneca will enter into a five-year research collaboration with the Harvard Stem Cell Institute in order to acclimatize a technique for the creation of human beta cells from stem cells for use in screens of AstraZeneca' s compound library to explore potential diabetes treatment options. In type 1 diabetes patients have to inject themselves with insulin to maintain blood glucose levels as beta cells are destroyed by an autoimmune response and in type 2 diabetes, beta cells either decrease or fail to function properly.

http://ift.tt/18Y2RlC

UA Cardiothoracic Surgeon Dr. Zain Khalpey Receives Prestigious Fulbright Award

Zain Khalpey, MD, PhD, FETCS , associate professor of surgery at the University of Arizona, surgical co-director of Heart Transplant and director of Mechanical Circulatory Support and Mitral Valve Program at Banner - University Medical Center Tucson , has been awarded a 2015-16 Fulbright U.S. Scholar. Awards in the Fulbright Distinguished Chairs Program are viewed as among the most prestigious appointments in the Fulbright Scholar Program.

http://ift.tt/1Iw1QO3

Fraunhofer-Institute Release: World Conference On Regenerative...

... before, the organizers expect 1,000 visitors presenting new approaches and findings in the fields of stem cell research, cell therapies, biomaterials and tissue engineering. In addition, ethical and legal aspects and regulatory affairs of ...

http://ift.tt/1NgVlzs

Researchers discover genetic origins of myelodysplastic syndrome using stem cells

In a process called cellular reprogramming, researchers at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with myelodysplastic syndrome and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer. The results appear in an upcoming issue of Nature Biotechnology .

http://ift.tt/1LZ8lP5

Why Some HPV Infections Go Away and Others Become Cancer

For people infected with the human papilloma virus , the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed. A new study finds that the body's ability to defeat the virus may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response.

http://ift.tt/1HGvi6l

Celprogen Released Stem Cell Active Ingredients for the Cosmetic...

Torrance, CA, March 25, 2015 -- -- Celprogen Inc., a leader in the Stem Cell Research and Therapeutics industry for the development of stem cell technologies for regenerative medicine, today announced that they have adult stem cell derived conditioned media containing stem cells growth components for the skin care regenerative products. These stem cell derived conditioned media have been utilized in skin care products for a decade.

http://ift.tt/1CPv8XG

Ebola pioneer, stem cell researcher honoured with Canada Gairdner Awards

Dr. Peter Piot, director of the London School of Hygiene and Tropical Medicine, speaks during an interview in London, Oct.17, 2014. Piot, one of the co-discoverers of the Ebola virus, and a leading Canadian stem cell researcher, are among this year's winners of the prestigious Canada Gairdner Awards.

http://ift.tt/1CPv6iA?

Mount Sinai Researchers Discover Genetic Origins of Myelodysplastic Syndrome Using Stem Cells

3D miniature lungs

Researchers from the University of Michigan have cooked-up the perfect recipe for growing miniature, three-dimensional human lungs from stem cells, but you won't find this recipe in a cookbook - it appears in the latest edition of the journal eLife . Lead author Dr. Jason Spence, a professor at the UM Medical School in Ann Arbor, and colleagues from the Cincinnati Children's Hospital Medical Center, the University of California, San Francisco , Seattle Children's Hospital and the University of Washington reported in their paper how they converted human pluripotent stem cells into mini lungs.

http://ift.tt/1btCA07

Hope for patients waiting for a transplant: 25 million stem cell...

A partner of BMDW since 2013, Hema-Quebec is proud to have contributed to this milestone that provides hope for health professionals and patients everywhere waiting for a transplant. Every year, thousands of people are diagnosed with a serious disease such as leukemia, another form of cancer or a hereditary condition.

http://ift.tt/1FGnbpS

Robert Lee Rann

Robert "Bobby" Lee Rann Robert "Bobby" Lee Rann, 56, of Saginaw died Thursday, March 19, 2015, in Dallas.

http://ift.tt/1FV4z3V

In Vivo Repopulating Activity Emerges at the Onset of Hematopoietic...

Stem Cell Reports , Vol. 4, No. 3. , pp. 431-444, doi:10.1016/j.stemcr.2015.01.003 To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.

http://ift.tt/19PNfSk

Combining old drug and new mehtod to kill cancer cells

Pairing a new approach with an old drug may be an effective approach to treat common cancers. In a landmark study, researchers identified a new signalling pathway that regulates the internal diet of cancers.

http://ift.tt/18XdJQN

EHT Eagles T-shirts pay tribute to former student

When Alexander Pearse was a student at Egg Harbor Township High School, he would blare music between classes from speakers mounted on his wheelchair. And though his disease claimed him March 15, it seems that his tune is being carried on by those who were touched by his upbeat approach to life.

http://ift.tt/19PNcG3

Enzyme discovered that keeps blood stem cells functional to prevent anemia

Stem cells can generate any type of cell in the body, but they are inactive most of the time - and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations.

http://ift.tt/19PNcpr

Ebola pioneer, stem cell researcher honoured with Canada's baby Nobels

Dr. Peter Piot won the 2015 Canada Gairdner Global Health Award in recognition of his work on the discovery of the Ebola virus in 1976 and his leadership in the global response to the HIV-AIDS epidemic. One of the co-discoverers of the Ebola virus and a leading Canadian stem cell researcher are among this year's winners of the prestigious Canada Gairdner Awards.

http://ift.tt/1GlumTg

Canadians honoured for medical research

One of the co-discoverers of the Ebola virus and a leading Canadian stem cell researcher are among this year's winners of the prestigious Canada Gairdner Awards. Dr. Peter Piot is the recipient of the Canada Gairdner Global Health Award, recognizing his work on the discovery of the Ebola virus in 1976 and his leadership in the global response to the HIV-AIDS epidemic.

http://ift.tt/1Glxoae

Cellular Biomedicine Group Announces Interim Results From Phase IIb...

Cellular Biomedicine Group Inc. , a biomedicine firm engaged in the development of effective treatments for degenerative and cancerous diseases, today announced interim 24-week clinical data from the Phase IIb trial of its ReJoinTM human adipose-derived mesenchymal progenitor cell therapy for Knee Osteoarthritis . The data will be discussed by Dr. Wei Cao, PhD, BM, Chief Executive Officer of Cellular Biomedicine Group at the 2015 Annual Regen Med Investor Day at the Metropolitan Club in New York City.

http://ift.tt/1BmCEoj

Scientists create functioning "mini-lungs" to study cystic fibrosis

The mini-lungs could be used to test the effectiveness of potential new drugs Researchers at the University of Cambridge have grown functional "mini-lungs" using stems cells derived from the skin cells of patients with a debilitating lung disease. Not only can the development help them in coming up with effective treatments for specific lung diseases like cystic fibrosis, but the process has the potential to be scaled up to screen thousands of new compounds to identify potential new drugs.

http://ift.tt/1xyqIEe

Ebola pioneer, stem cell researcher honoured with Canada Gairdner Awards

Cellular Biomedicine Group Announces Phase I Results From CAR-T...

Cellular Biomedicine Group Inc. , a biomedicine firm engaged in the development of effective treatments for degenerative and cancerous diseases, today announced clinical data from its CAR-T immuno-oncology clinical development programs. The data will be discussed by Dr. Wei Cao, PhD, BM, Chief Executive Officer of Cellular Biomedicine Group, at the 2015 Annual Regen Med Investor Day on March 25 in New York City.

http://ift.tt/1IuMyZT

Cellular Biomedicine Group Announces Interim Results From Phase IIb...

AstraZeneca to Collaborate With the Harvard Stem Cell Institute in Diabetes

AstraZeneca has entered into a five-year research collaboration with the Harvard Stem Cell Institute to adapt a technique that creates human beta cells from stem cells for use in screens of AstraZeneca's compound library in the search for new treatments for diabetes. The collaboration also aims to better understand how the function of beta cells declines in diabetes and research findings will be made available to the broader scientific community through peer-reviewed publications.

http://ift.tt/19kTUTc

Gairdners honour researcher who went from outsider to stem-cell pioneer

... Dr. Rossant would later bring to SickKids and to her term as president of the International Society for Stem Cell Research in 2013. By then, Dr. Rossant had long since stopped being an outsider, and was instead a central player and a champion. "She ...

http://ift.tt/1CXVuIB

Kidney is Focus of 3rd Solving Organ Shortage Science Summit to...

Top academic investigators and clinicians from leading U.S. research universities will gather in Austin, Texas, September 10-11 to participate in the Kidney Regeneration & Bioengineering State-of-the-Science Summit , the third organ-specific summit convened by Solving Organ Shortage in little over a year, to focus research on regenerating or engineering solid organs for human transplant.

http://ift.tt/1bsWsjX

View Press Release

Kidney is Focus of 3 rd Solving Organ Shortage Science Summit to Advance Research to Regenerate or Bioengineer Organs for Human Transplant )--Top academic investigators and clinicians from leading U.S. research universities will gather in Austin, Texas, September 10-11 to participate in the Kidney Regeneration & Bioengineering State-of-the-Science Summit , the third organ-specific summit convened by Solving Organ Shortage in little over a year, to focus research on regenerating or engineering solid organs for human transplant.

http://ift.tt/1y5IzNa

Press release distribution, EDGAR filing, XBRL, regulatory filings

Allied World Assurance Company Holdings, AG a OEa a a1 2Si1 4 e 2a... a a ae-1 42015a1 4aeoeS22ae- i1 4Se a )--U.S. retailers must move quickly to improve their operational capabilities in order to deliver a seamless retail experience to customers who say their expectations are no... )--Accenture will host a conference call at 8:00 a.m. EDT tomorrow, Mar. 26, to discuss its second-quarter fiscal year 2015 financial results.

http://ift.tt/1ESiQwE

Osiris Therapeutics to Present at the 3rd Annual Regen Med Investor Day

... in biotechnology by focusing on innovation in regenerative medicine - including bioengineering, stem cell research and viable tissue based products. Osiris has achieved commercial success with products in orthopaedics, sports medicine and wound ...

http://ift.tt/19kzgTl

Mesenchymal stem cell transplantation reduces opioid tolerance, opioid-induced pain

Mesenchymal stem cell transplantation reduced opioid tolerance and opioid-induced hyperalgesia caused by daily morphine injections in rats, according to new research. The results could herald stem cell transplantation as an innovative, safe, efficacious and cost-effective therapy to treat pain and opioid tolerance, said researchers, who presented results in a Plenary Research Highlight session at the 31st Annual Meeting of the American Academy of Pain Medicine.

http://ift.tt/1GTo7En

Scientists coax stem cells to form 3-D mini lungs

Scientists, led by the University of Michigan Medical School, coax stem cells to form mini lungs, 3-D structures that mimic human lungs and survived in the lab for 100 days. Credit: University of Michigan Health System Previous research has focused on deriving lung tissue from flat cell systems or growing cells onto scaffolds made from donated organs.

http://ift.tt/1COgXSF

Obs-Gyne exhibition to highlight women's health in the region

PRLog - March 25, 2015 - DUBAI, UAE -- Dubai, UAE: The 7th Obs-Gyne Exhibition and Congress kicks off in Dubai on Sunday next week. The event will showcase 50 regional and international leading companies in the field of fertility, obstetrics, gynaecology, midwifery and women's health.

http://ift.tt/19khwr0

New treatment for mantle cell lymphoma (MCL) now available for patients in the UK

VELCADE has been approved today in the UK for the first-line treatment of Mantle Cell Lymphoma , an aggressive subtype of blood cancers , collectively known as Non-Hodgkin Lymphoma . Recent clinical trial results have shown that patients with previously untreated MCL, who were unsuitable for blood stem-cell transplantation, had an improvement in progression free survival compared to the control arm when treated with bortezomib in combination with rituximab, cyclophosphamide, doxorubicin and prednisone .

http://ift.tt/1GjJSiu

Duke researchers develop new model to study why some HPV infections go away and others progress

For people infected with the human papilloma virus , the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed. A new study finds that the body's ability to defeat the virus may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response.

http://ift.tt/1GSOnic

University of Michigan scientists grow first 3D mini lungs from human stem cells

Scientists from the University of Michigan have grown the first 3D mini lungs from stem cells. The study, published in eLife , compliments other developments in the field such as growing mainly 2D structures and building lung tissue from the scaffold of donated organs.

http://ift.tt/1xfNlN5

Assessment of Cardiomyocyte Contraction in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Fax: Functional changes to cardiomyocytes are a common cause of attrition in preclinical and clinical drug development. Current approaches to assess cardiomyocyte contractility in vitro are limited to low-throughput methods not amenable to early drug discovery.

http://ift.tt/1bs08m4

Tuesday, March 24, 2015

Recipe For How To Grow A Human Lung

Scientists have grown the first 3-D mini lungs from stem cells, which means research is one step closer to being able to create one of the Big 5 organs from a patient's stem cells rather than having waiting lists for donors. The University of Michigan scientists succeeded in growing structures resembling both the large proximal airways and the small distal airways.

http://ift.tt/1BkkoMq

How to grow a human lung

Chance Helps Explain Why Some HPV Infections Go Away and Others Become Cancer

For people infected with the human papillomavirus , the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed. A new study finds that the body's ability to defeat the virus may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response.

http://ift.tt/1xfeTSJ

Athersys: An Ischemic Stroke Holy Grail? Find Out In Less Than A Month

Athersys is a development stage biotech that fully enrolled a Phase 2 stem cell trial for ischemic stroke at the end of 2014. Results will likely be a binary event: company crippling or validating MultiStem for ischemic stroke and many other significant indications.

http://ift.tt/1IrYNqa

Why Some HPV Infections Go Away and Others Become Cancer

For people infected with the human papilloma virus , the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed. A new study finds that the body's ability to defeat the virus may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response.

http://ift.tt/1FC6ls1

Cleveland Clinic Researchers First to Demonstrate Significant...

March 24, 2015, NATIONAL HARBOR, Md. -- Mesenchymal stem cell transplantation reduced opioid tolerance and opioid-induced hyperalgesia caused by daily morphine injections in rats, according to new research.

http://ift.tt/1EEKUB3

Why some HPV infections go away and others become cancer

For people infected with the human papilloma virus , the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed. A new study finds that the body's ability to defeat the virus may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response.

http://ift.tt/1Hy7deA

President of Japan's RIKEN research labs resigns

RIKEN president Ryoji Noyori at his resignation press conference. He will be replaced by Hiroshi Matsumoto .

http://ift.tt/1FBqkXV

Ocata Therapeutics Licenses Induced Pluripotent Stem Cell...

Ocata Therapeutics, Inc. , a leader in the field of Regenerative Ophthalmologya , today announced that it has entered into a definitive agreement with Allele Biotechnology & Pharmaceuticals, Inc. of San Diego, CA to access Allele's proprietary technology for generating human induced pluripotent stem cells . "Ocata can now take advantage of induced and embryonic pluripotent stem cells to produce commercially viable human tissue for transplantation.

http://ift.tt/1NbOrLU

Regen BioPharma Expands Research Capacity With New Laboratory Facilities

Blues To Hold Finn McEwen Appeal Event

Everton are backing an appeal for Finn McEwen, a seven-year-old boy from Liverpool, by holding a registration event at Goodison Park. The appeal has received widespread support from across the country including from Everton, the team that Finn is a huge fan of.

http://ift.tt/1Oxh89w

Paul Sanberg of the University of South Florida Named 2015 Medalist...

... Medal of Technology and Innovation. He is the founder of several health-related companies and his work in stem cell research has helped to lay the foundation for the new field of regenerative medicine. through the publication of its quarterly ...

http://ift.tt/1HAkvdS

Why some HPV infections go away and others become cancer

For people infected with the human papilloma virus , the likelihood of clearing the infection and avoiding HPV-related cancer may depend less on the body's disease-fighting arsenal than has been generally assumed. A new study finds that the body's ability to defeat the virus may be largely due to unpredictable division patterns in HPV-infected stem cells, rather than the strength of the person's immune response.

http://ift.tt/19icyLs

Functional annotation of native enhancers with a Cas9-histone demethylase fusion

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Understanding of mammalian enhancers is limited by the lack of a technology to rapidly and thoroughly test the cell type-specific function.

http://ift.tt/1CmJKgu

Scientists coax stem cells to form 3-D mini lungs

Previous research has focused on deriving lung tissue from flat cell systems or growing cells onto scaffolds made from donated organs. In a study published in the online journal eLife the multi-institution team defined the system for generating the self-organizing human lung organoids, 3D structures that mimic the structure and complexity of human lungs.

http://ift.tt/1y1NVcx

Semma Therapeutics nets $44 mln

Semma Therapeutics, a company developing a cell therapy for Type 1 diabetes, announced today that it has closed a $44 million Series A consisting of equity financing and strategic funding. The Series A financing is led by MPM Capital, with Fidelity Biosciences, ARCH Venture Partners, and Medtronic participating.

http://ift.tt/1FAt6fT

Marlboro's Ocata in deal with Allele Biotechnology

Ocata Therapeutics Inc. has reached an agreement to use technology from Allele Biotechnology & Pharmaceuticals Inc. to generate human stem cells. Terms were not disclosed.

http://ift.tt/1FAt47L

Ridgewood cancer patient seeks donor match

With any luck, that miracle will come April 18, when another donor drive will be held in Hillsdale, aimed at finding possible matches for the 23-year-old Ridgewood man, who has been battling an aggressive form of Hodgkin's lymphoma for several years. The drive is being organized by Delete Blood Cancer - the U.S. unit of the German Bone Marrow Donor Center - in conjunction with the Devils and Goldman Sachs.

http://ift.tt/1CVeHuq

This Brooks Ayers News Is Devastating...

Vicki Gunvalson has been by her boyfriend Brooks Ayers' side quite a lot lately, as the handsome reality man is battling stage 3 non-Hodgkin lymphoma. Unfortunately, the chemotherapy he's been under hasn't been working.

http://ift.tt/1y1xm0k

Ocata Therapeutics Licenses Induced Pluripotent Stem Cell Technology from Allele Biotechnology and Extends Leadership Position in Cell Therapy Capabilities

Ocata Therapeutics, Inc. , a leader in the field of Regenerative Ophthalmology, today announced that it has entered into a definitive agreement with Allele Biotechnology & Pharmaceuticals, Inc. of San Diego, CA to access Allele's proprietary technology for generating human induced pluripotent stem cells . "This agreement with Allele is part of our strategy to broaden our technology platform and increase our leadership in regenerative ophthalmology," said Paul Wotton Ph.D., President and CEO of Ocata.

http://ift.tt/1y1qNea

Stemedica Obtains An Exclusive Worldwide License For Stem Cell...

Stemedica Cell Technologies Inc., , announced today that Universal Stabilization Technologies has granted to Stemedica subsidiary StemProtein, LLC, an exclusive worldwide license to its technology known as Preservation by Vaporization for industrial scale stabilization of stem cells and stem cell derivatives. This license will allow Stemedica and StemProtein to manufacture stem cell-secreted therapeutic proteins in a VitriLife state, that remain shelf stable and therapeutically active at ambient temperatures for two or more years.

http://ift.tt/1y1qKil

Semma Therapeutics Announces $44 Million in Funding Led by MPM...

Accellta Grants Exclusive Rights for Micro-Carrier Free Stem Cells...

The stem cell company Accellta announced today that it has granted exclusive worldwide rights to STEMCELL Technologies Inc. for manufacturing and distribution of medium for culturing pluripotent stem cells in suspension under feeder-free, non-adherent conditions. The novel medium represents a breakthrough in stem cell manufacturing technologies; it was designed by Accellta to dramatically reduce the cost and duration of pluripotent stem cell production by enabling mass culturing of cells in suspension, using a bioreactor free of micro-carriers or any other adherence surfaces, which replaces the use of numerous culture dishes or micro-carriers.

http://ift.tt/1DTtXrN

Scientists coax stem cells to form 3D mini lungs

Scientists have coaxed stem cells to grow the first three-dimensional mini lungs. The 3D structures mimic the complexity of human lungs and may serve as a discovery tool for lung diseases or new therapies.

http://ift.tt/1LSOjFV

A tale of two siblings: two cases of AML arising from a single pre-leukemic DNMT3A mutant clone

Acute myeloid leukemia patients with DNA methyltransferase 3A mutations in remission after induction chemotherapy may have hematopoiesis arising from a putative pre-leukemic clone lacking the full spectrum of mutations seen at AML diagnosis. 2 DNMT3A mutations in hematopoietic stem cells lead to increased self-renewal capacity and dominance of the stem-cell compartment.

http://ift.tt/1GcPVFK

Passenger Plane Crashes Over Alps, UVA Frat May Sue Rolling Stone ,...

Editor's Note : We invite comments and request that they be civil and on-topic. We do not moderate or assume any responsibility for comments, which are owned by the readers who post them.

http://ift.tt/1LSyf6T

Boston Startup Reels in $44 Million; In Process of Hiring and Leasing Lab Space

Anew Cambridge biotech will be working on a treatment using stem cells that could let children and adults with Type 1 diabetes do something their bodies currently cannot: produce their own insulin, the hormone that keeps blood sugar levels in balance. Semma Therapeutics is already off to a strong start.

http://ift.tt/1Fzuks3

Scientists coax stem cells to form 3-D mini lungs

Scientists Coax Stem Cells to Form 3D Mini Lungs

Scientists coax stem cells to form 3-D mini lungs

ItpkB enzyme regulates stem cells function to prevent cancer, anemia

Biotech startup to fight diabetes on the cellular front

Asymmetrex Opens Up 5th World Congress on Cell and Stem Cell Research ...

The 5th World Congress on Cell and Stem Cell Research in Chicago was opened yesterday by two presentations from Boston stem cell biotechnology start-up company Asymmetrex. The company's director, James L. Sherley, M.D., Ph.D., set the stage for the first day of talks that were focused on stem cell medical engineering.

http://ift.tt/1BepdXs

The role of growth factors in stem cell-directed chondrogenesis: a...

Purpose The use of stem cells in regenerative medicine offers hope to treat numerous orthopaedic disorders, including articular cartilage defects. Although much research has been carried out on chondrogenesis, this complicated process is still not well understood and much more research is needed.

http://ift.tt/1N9pLDG

Monday, March 23, 2015

Leigh Steinberg Blog: Chris Borland Decision Spurs NFL Safety Dialogue

When a young NFL player facing a promising future walks away from the sport, it is a clarion call for evaluating the risks posed by concussion. Chris Borland had it all-the American Dream.

http://ift.tt/1HvMzis

Why does hair change colour and turn grey?

Most of us find our first "greys" by the time we turn 30, usually at the temples, then later, across the scalp. While many people find the salt and pepper look appealing, others go to great lengths to conceal these locks.

http://ift.tt/1CL8cJd

Combining the old and new to kill cancer cells

Removal of enzyme CK1 blocks cellular digestion in specific cancers. Credit: Dr. Jit Kong Cheong / Duke-NUS Graduate Medical School Singapore A team of Singapore based scientists have found that pairing a new approach with an old drug may be an effective approach to treat common cancers.

http://ift.tt/1N21iCg

Combining the old and new to kill cancer cells

A team of Singapore based scientists have found that pairing a new approach with an old drug may be an effective approach to treat common cancers. In a landmark study, Professor David Virshup and Dr. Jit Kong Cheong, from Duke-NUS Graduate Medical School Singapore , identified a new signalling pathway that regulates the internal diet of cancers.

http://ift.tt/1IlIFGA

TSRI Team Discovers Enzyme that Keeps Blood Stem Cells Functional to Prevent Anemia

March 23, 2015 - Stem cells can generate any type of cell in the body, but they are inactive most of the time-and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations.

http://ift.tt/1CiRtMP

City of Hope Launches Stem Cell Therapy Clinic To Fight Incurable Disease In New Ways

In the field of cancer, patients have had surgery, chemotherapy and radiation therapy as options. Now, as City of Hope officially opens the Alpha Clinic for Cell Therapy and Innovation, patients battling cancer and other life-threatening diseases have another option: stem cell-based therapy.

http://ift.tt/1G6pnWv

Clontech Laboratories, Inc. Signs Agreement With For Access To Smart-Seq2

As a result of this agreement, Clontech will become the exclusive supplier of SMART-Seq2 technology. "We have a strong interest in advancing single-cell RNA-seq technology and applications, and we are deeply committed to continuing to develop products that will enable such advances by boosting assay sensitivity for studies essential to a wide variety of biological fields," commented , President of Clontech Laboratories, Inc. "Our focus continues to be on providing new solutions to customers, enabling them to work with the most challenging samples."

http://ift.tt/1CRC5sS

Pages

Web Stats Provided By Google Analytics

The Raw Stem Cell News Feed

Tuesday, March 31, 2015

Monday, March 30, 2015

Sunday, March 29, 2015

Saturday, March 28, 2015

Friday, March 27, 2015

Thursday, March 26, 2015